Jennifer Jeanne B. Vicera

Taipei Veterans General Hospital

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Yenn‐Jiang Lin

Taipei Veterans General Hospital

Yu‐Feng Hu

National Yang Ming Chiao Tung University

Chin‐Yu Lin

National Tsing Hua University

Jo‐Nan Liao

National Yang Ming Chiao Tung University

Ta‐Chuan Tuan

National Yang Ming Chiao Tung University

Li‐Wei Lo

National Yang Ming Chiao Tung University

Chih‐Min Liu

National Yang Ming Chiao Tung University

Tze‐Fan Chao

National Yang Ming Chiao Tung University

Ting‐Yung Chang

Taipei Veterans General Hospital

Fa‐Po Chung

Taipei Veterans General Hospital

Cooperative Institutions

Taipei Veterans General Hospital

National Yang Ming Chiao Tung University

National Yang Ming University Hospital

Meenakshi Mission Hospital and Research Centre

National Taipei University

Siriraj Hospital

Mahidol University

Oita University

Kyushu University Hospital

Fuji Heavy Industries Health Insurance Society Ota Memorial Hospital

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Clinical significance of J wave in prediction of ventricular arrhythmia in patients with acute myocardial infarction

Journal of Cardiology (2018)

Cheng‐I Wu Shih‐Lin Chang Chin‐Yu Lin Jennifer Jeanne B. Vicera Yenn‐Jiang Lin

10.1016/j.jjcc.2018.11.005

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Citations (3)

Electrophysiological and clinical characteristics of catheter ablation for isolated left side atrial tachycardia over a 10‐year period

Journal of Cardiovascular Electrophysiology (2019)

Jennifer Jeanne B. Vicera Yenn‐Jiang Lin Chin‐Yu Lin Dai‐Yin Lu Shih‐Lin Chang

Most left atrial tachycardia (LAT) is associated with atrial fibrillation (AF). The clinical and electrophysiological characteristics and outcomes of LAT without AF have not been investigated. This study sought to determine the long-term ablation outcomes and predictors of recurrence of isolated LAT.This is a single-center study of consecutive patients with isolated LAT. Atrial arrhythmia recurrence was determined from follow-up records of patients who underwent LAT ablation from 2008 to 2017. Clinical and electrophysiologic characteristics associated with atrial arrhythmia recurrence were identified.A total of 50 patients (53 ± 19 years, 46% male) with 59 LAT (1.16 ± 0.47 per patient) were enrolled. Over a mean follow-up of 37 ± 33 months, atrial arrhythmia recurrence occurred in 22 (44%) patients, 11 with atrial tachycardia (AT) only, five with AF only, and six with concurrent AT and AF. The incidence of pulmonary vein (PV) origins increased significantly in the repeat procedure (P = 0.036). Multivariate analysis identified left ventricular ejection fraction (LVEF) as the only predictor of any atrial arrhythmia recurrence and LAT recurrence, while smoking and identified macroreentrant LAT in the index procedure predicted AF recurrence.This study demonstrated a higher rate of atrial arrhythmia recurrence, including AF, among patients with initially isolated LAT. A lower LVEF predicted any atrial arrhythmia and LAT recurrence, whereas smoking and index macroreentrant AT mechanism predicted long-term AF. PV ATs were frequently observed in recurrent patients irrespective of index procedure origin.

Atrial tachycardia

10.1111/jce.13945

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2021 Asia‐Pacific League of Associations for Rheumatology clinical practice guideline for treatment of gout

International Journal of Rheumatic Diseases (2021)

Jose Paulo Lorenzo Ma. Hanna Monica Z. Sollano Evelyn O. Salido Julie Li‐Yu Sandra A. Tankeh‐Torres

Abstract Background Gout is the most prevalent inflammatory arthritis in the Asia‐Pacific region and worldwide. This clinical practice guideline (CPG) aims to provide recommendations based on systematically obtained evidence and values and preferences tailored to the unique needs of patients with gout and hyperuricemia in Asia, Australasia, and the Middle East. The target users of these guidelines are general practitioners and specialists, including rheumatologists, in these regions. Methods Relevant clinical questions were formulated by the Steering Committee. Systematic reviews of evidence were done, and certainty of evidence was assessed using Grading of Recommendations Assessment, Development and Evaluation methodology. A multi‐sectoral consensus panel formulated the final recommendations. Results The Asia‐Pacific League of Associations for Rheumatology Task Force developed this CPG for treatment of gout with 3 overarching principles and 22 recommendation statements that covered the treatment of asymptomatic hyperuricemia (2 statements), treatment of acute gout (4 statements), prophylaxis against gout flare when initiating urate‐lowering therapy (3 statements), urate‐lowering therapy (3 statements), treatment of chronic tophaceous gout (2 statements), treatment of complicated gout and non‐responders (2 statements), treatment of gout with moderate to severe renal impairment (1 statement), and non‐pharmacologic interventions (5 statements). Conclusion Recommendations for clinically relevant scenarios in the management of gout were formulated to guide physicians in administering individualized care.

Guideline

Febuxostat

10.1111/1756-185x.14266

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Citations (32)

The impact of height on recurrence after index catheter ablation of paroxysmal atrial fibrillation

Journal of Interventional Cardiac Electrophysiology (2021)

Shin-Huei Liu Li‐Wei Lo Fa‐Po Chung Shih‐Lin Chang Yu‐Feng Hu

Quartile

10.1007/s10840-021-01055-2

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Novel electrophysiological criteria for septal ventricular outflow tract tachycardias requiring a sequential bilateral ablation

Journal of Cardiovascular Electrophysiology (2017)

Chin‐Yu Lin Fa‐Po Chung Yenn‐Jiang Lin Shih‐Lin Chang Li‐Wei Lo

Abstract Background Septal ventricular outflow tract ventricular arrhythmias (OT‐VAs) are defined as septal origin VAs from the right ventricular or left ventricular OT. Patients with septal OT‐VAs may require a sequential bilateral OT ablation. This study aimed to evaluate the electrophysiological characteristics and ablation outcome in patients with septal OT‐VAs. Methods We retrospectively analyzed the electrocardiography and electrophysiological parameters in 96 patients (mean age 49 ± 15 years, 49 male) undergoing bilateral activation mapping before catheter ablation of idiopathic septal OT‐VAs. The patients were categorized into three groups based on the successful ablation sites, including the right ventricular outflow tract (RVOT), RVOT/left ventricular outflow tract (LVOT), and LVOT. Results Mapping in the three groups demonstrated a gradually decreasing and increasing trend in the earliest activation time obtained from the RVOT and LVOT, respectively. The absolute earliest activation time discrepancy (AEAD) of ≤18 milliseconds could predict the requirement for a sequential bilateral ablation with a sensitivity and specificity of 100.0% and 93.7%, respectively. The small AEAD (≤21 milliseconds) was associated with a higher recurrence rate in patients receiving a successful unilateral ablation, while patients with a longer distance between the bilateral OT earliest activation sites (DEA > 26 mm) increased future recurrences after an initially successful sequential bilateral ablation. Conclusions The application of bilateral OT‐VA activation mapping and the measurement of the AEAD and DEA provided not only pivotal information for the ablation strategy, but also prognostic implications for recurrences in patients with septal OT‐VAs.

Ventricular outflow tract

10.1111/jce.13376

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Citations (2)

Extremely late recurrences (≥3 years) of atrioventricular nodal reentrant tachycardia: Electrophysiological characteristics of the index and repeat ablation procedures

International Journal of Cardiology (2020)

Chye‐Gen Chin Fa‐Po Chung Yenn‐Jiang Lin Shih‐Lin Chang Li‐Wei Lo

10.1016/j.ijcard.2020.02.007

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High-resolution mapping of pulmonary vein potentials improved the successful pulmonary vein isolation using small electrodes and inter-electrode spacing catheter

International Journal of Cardiology (2018)

Chin‐Yu Lin Abigail Louise D. Te Yenn‐Jiang Lin Shih‐Lin Chang Li‐Wei Lo

Isolation

10.1016/j.ijcard.2018.06.062

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Citations (17)

Isolated Non-Compacted Right Ventricular Myocardium with Severe Pulmonary Hypertension

GSTF Journal of Advances in Medical Research (2014)

Jennifer Jeanne B. Vicera Wilson Tan-De Guzman Eduardo Vicente Caguioa

Right ventricular failure

10.5176/2345-7201_1.1.02

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Optimal substrate modification strategies using catheter ablation in patients with persistent atrial fibrillation: 3‐year follow‐up outcomes

Journal of Cardiovascular Electrophysiology (2021)

Yu‐Cheng Hsieh Yenn‐Jiang Lin Men‐Tzung Lo Yun‐Yu Chen Chin‐Yu Lin

Abstract Objectives This study aimed to assess the comparative efficacy of four ablation strategies on the incidence rates of freedom from atrial fibrillation (AF) or atrial tachycardia (AT) through a 3‐year follow‐up in patients with persistent AF. Background The optimal substrate modification strategies using catheter ablation for patients with persistent AF remain unclear. Methods Patients with persistent AF were enrolled consecutively to undergo each of four ablation strategies: (a) Group 1 (Gp 1, n = 69), pulmonary vein isolation (PVI) plus rotor ablation assisted by similarity index and phase mapping; (b) Gp 2 ( n = 75), PVI plus linear ablations at the left atrium; (c) Gp 3 ( n = 42), PVI plus the elimination of complex fractionated atrial electrograms; (d) Gp 4 ( n = 67), PVI only. Potential confounders were adjusted via a multivariate survival parametric model. Results Baseline characteristics were similar across the four groups. At a follow‐up period of 34.9 ± 38.6 months, patients in Gp 1 showed the highest rate of freedom from AF compared with the other three groups ( p = .002), while patients in Gp 3 and 4 showed lower rates of freedom from AT than those of the other two groups ( p = .006). Independent predictors of recurrence of AF were the ablation strategy ( p = .002) and left atrial diameter (LAD) ( p = .01). Conclusion In patients with persistent AF, a substrate modification strategy using rotor ablation assisted by similarity index and phase mapping provided a benefit for maintaining sinus rhythm compared with the other strategies. Both ablation strategy and baseline LAD predicted the 3‐year outcomes of freedom from AT/AF

Cardiac Ablation

10.1111/jce.15033

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Citations (4)

Oral anticoagulant use for stroke prevention in atrial fibrillation patients with difficult scenarios

IJC Heart & Vasculature (2018)

Ting‐Yung Chang Jo‐Nan Liao Tze‐Fan Chao Jennifer Jeanne B. Vicera Chin‐Yu Lin

Atrial fibrillation (AF) has become the most prevalent arrhythmia and it will increase the risk of ischemic stroke, heart failure, mortality, sudden cardiac death, myocardial infarction, and dementia. Stroke prevention with oral anticoagulant is crucial for management of AF patients. Vitamin K antagonist, which inhibits the clotting factors II, VII, IX and X, has been recommended for stroke prevention for decades. Non-Vitamin K antagonist oral anticoagulants (NOACs), including dabigatran, rivaroxaban, apixaban and edoxaban are at least as effective as warfarin in reducing ischemic stroke with a lower rate of major bleeding. With the increasing prevalence of AF, prescription of the appropriate oral anticoagulants (OACs) according to patient's characteristics becomes a challenge. This review article aims to provide an overview of anticoagulant use in AF patients with difficult scenarios.

Apixaban

Edoxaban

Vitamin K antagonist

Stroke

10.1016/j.ijcha.2018.08.003

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Citations (38)