To compare the incidence of intraoperative and early postoperative complications (IEPC), visual outcomes, and change in intraocular pressure (IOP) between eyes with and without pseudoexfoliation syndrome (PEX) having cataract extraction by phacoemulsification.800 eyes with PEX and 1,600 eyes without PEX having cataract extraction by phacoemulsification were included in this retrospective study. Evaluated parameters were incidence of IEPC, visual outcomes and change in IOP. chi2 and Student's t test were used for statistical analysis.There were no significant differences in the incidence of IEPC and visual acuity gain between the two groups (p > 0.05). Rise in IOP in the early postoperative period was significantly higher in the PEX group (p < 0.02).Patients with PEX who have phacoemulsification can achieve results similar to patients without PEX. IOP control in the early postoperative period seems to be more important in patients with PEX.
Age-related macular degeneration (AMD) is the leading cause of visual impairment in developed countries. Studies have been going on for the treatment of an exudative form of the disease for years. In recent years after the investigation of anti-VEGF agents, medical treatments have become the main treatment option for this disease. Surgical treatment modalities are macula translocation, submacular surgery, and retina pigment epithelium (RPE) transplantation. Nowadays because of high complication rates and difficult surgical techniques surgical treatment use only chose cases with limited indications.
In Brief Purpose: The purpose of this study was to evaluate the results of phacoemulsification with intravitreal bevacizumab injection in patients with diabetic clinically significant macular edema and cataract. Methods: The records of 31 patients with diabetic clinically significant macular edema and cataract, which would interfere with macular laser photocoagulation, who have undergone phacoemulsification with intravitreal injection of 1.25 mg bevacizumab were retrospectively evaluated. All patients had undergone focal or modified grid laser photocoagulation 1 month after the surgery. All patients were evaluated by spectral optical coherence tomography/optical coherence tomography SLO before and 1 and 3 months after the surgery beyond complete ophthalmologic examination. The best-corrected visual acuity (BCVA) levels and central macular thickness (CMT) recorded at the first and third months after the surgery were compared with the initial values. Paired samples t test was used for statistical analysis. Results: The mean initial BCVA was 0.10 ± 0.04 (range, 0.05-0.2). The mean BCVA at the first and third months after the surgery were 0.47 ± 0.16 (standard deviation) (range, 0.2-0.5) and 0.51 ± 0.12 (standard deviation) (range, 0.3-0.6), respectively. The BCVA level recorded at the first and third months after the surgery were significantly higher than the initial BCVA (P = 0.004). The mean initial CMT was 387.5 ± 109.5 μm. The mean CMT at the first and third months after the surgery were 292.7 ± 57.2 and 275.5 ± 40.3. The CMT recorded at the first and third months after the surgery were significantly lower than the initial CMT (P < 0.001, P < 0.001). Conclusion: Phacoemulsification with intravitreal injection of bevacizumab provides improvement in clinically significant macular edema with a gain in BCVA in patients with diabetes with clinically significant macular edema and cataract. Phacoemulsification with intravitreal injection of bevacizumab provides improvement in clinically significant macular edema with a gain in best corrected visual acuity in patients with diabetes with clinically significant macular edema and cataract.
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