Aakanchha Jain

National Institute of Pharmaceutical Education and Research

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Richa Jain

People’s University

Sourabh Jain

Koneru Lakshmaiah Education Foundation

Tejas Girish Agnihotri

National Institute of Pharmaceutical Education and Research

Shyam Sudhakar Gomte

National Institute of Pharmaceutical Education and Research

Sourabh Jain

Indian Institute of Information Technology Allahabad

Biswajit Rout

National Institute of Pharmaceutical Education and Research

Shiv Kumar Prajapati

GLA University

Vasu Peddinti

National Institute of Pharmaceutical Education and Research

Shivani Khopade

National Institute of Pharmaceutical Education and Research

Richa Jain

Banasthali University

Cooperative Institutions

National Institute of Pharmaceutical Education and Research

Dr. Hari Singh Gour University

Government of India

Swami Ramanand Teerth Rural Medical College

Birla Institute of Technology and Science, Pilani

Creative Commons

People’s University

All India Institute of Medical Sciences

Roland Institute of Pharmaceutical Sciences

Universidade Federal de Alagoas

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Meropenem-Loaded Nanostructured Lipid Carriers For Skin and Soft Tissue Infection Caused by Staphylococcus aureus: Formulation, Design, and Evaluation

AAPS PharmSciTech (2022)

Kshipra Rajpoot Shiv Kumar Prajapati Akanksha Malaiya Richa Jain Aakanchha Jain

Stearic acid

Zeta potential

Solid lipid nanoparticle

10.1208/s12249-022-02381-y

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Citations (8)

Harnessing the power of inorganic nanoparticles for the management of TNBC

International Journal of Pharmaceutics (2025)

Biswajit Rout Prashant Janjal Rushikesh Sanjay Shewale Vasu Peddinti Tejas Girish Agnihotri

10.1016/j.ijpharm.2025.125333

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Quantitative Determination of TNF Alpha and Interleukin-6

Springer protocols handbooks/Springer protocols (2020)

Aakanchha Jain Richa Jain Sourabh Jain

Cytokines are key regulators of immune responses in cancer. Cytokines are involved in amazingly broad array of biological activities including innate immunity, adaptive immunity, inflammation, and hematopoiesis. In addition to cytotoxic T cells, there are helper T cells (T H cells), whose function is to produce soluble signaling proteins called cytokines, which include the interleukins that stimulate TC, TH, and B cells to proliferate, activate, and stimulate different classes of leukocytes and possible uses in treatment of wounds, HIV infection, cancer, and immune deficiencies. Interleukin (IL) is one of several proteins important for lymphocyte proliferation. IL-1 is produced by macrophages and induces the production of IL-2 by T cells that have been stimulated by antigen or mitogen. IL-2 stimulates the production of T cells bearing specific receptor for IL-2; these receptors are expressed in response to the antigenic stimulation. IL-2 also seems to induce the production of interferon and is used as an anticancer drug in the treatment of wide variety of solid malignant tumors. Another interleukin, IL-3, is necessary for the differentiation of suppressor T cells. They can modulate tumor growth and microenvironment by mediating interactions between cancer cells and infiltrating inflammatory cells. On the basis of their function, cytokines can be grouped into anti- or pro-inflammatory cytokines, chemokines, and growth factors. Moreover, the classification into Th1 and Th2 cytokines is of importance. In general, Th1-type cytokines, e.g., interleukin (IL-12, IL-15) and interferon ɣ (IFN- γ), contribute to cellular immune reactions considered essential for an effective response against tumor cells, whereas Th2-type cytokines, e.g., IL-4, IL-6, IL-10, and IL-13, may suppress the tumor-specific immune response.

10.1007/978-1-4939-9861-6_27

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Determination of Serum Total Cholesterol

Springer protocols handbooks/Springer protocols (2020)

Aakanchha Jain Richa Jain Sourabh Jain

Cholesterol is a type of fat (lipid) present in the body that can be measured in blood serum and blood plasma and exists as free and esterified form. Cholesterol is vital constituent of the cell membranes, bile, brain, and nerve cells and benefits the body to absorb fats and fat-soluble vitamins. Cholesterol is also used in the formation of hormones such as cortisol, forms testosterone by the testicles, and forms estrogen and progesterone by the ovaries too. Normally it ranges from 150 to 200 mg/100 mL in adults. The level of cholesterol increases by 20–25% during pregnancy. The level of cholesterol increases in case of biliary obstruction, biliary cirrhosis, diabetes mellitus, hypothyroidism, nephrotic syndrome, and pancreatic disease.

10.1007/978-1-4939-9861-6_49

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Sub-culturing of Bacteria, Fungi and Actinomycetes

Springer protocols handbooks/Springer protocols (2020)

Aakanchha Jain Richa Jain Sourabh Jain

Microbial growth is defined as increase in number and/or biomass. All microorganisms require food, oxygen, moisture, and space for growth. Like any other living organisms, they age, and their growth is inhibited in the absence of food, space, oxygen, etc. In order to sustain any microbial culture in laboratory conditions, sub-culturing is required. Sub-culturing is a procedure of transferring of microorganism into fresh nutritive medium from its stock culture. It includes transfer of culture from slant to slant, slant to plate, plate to plate, plate to slant, solid medium to broth, and broth to solid media. Sub-culturing is done to maintain culture in its active form (prolonging life and/or increase the number of cells) for varied applications.

Bacterial growth

10.1007/978-1-4939-9861-6_29

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Development of antidiabetic poly herbal sustained release formulation composed of traditional Indian plant extract with their protective effect on antioxidant enzyme

Pancreatology (2018)

Aakanchha Jain Saurabh Bhargav Sourabh Jain

Parenchyma

Univariate analysis

Distal pancreatectomy

10.1016/j.pan.2018.05.102

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Citations (1)

Digital Colony Counter

Springer protocols handbooks/Springer protocols (2020)

Aakanchha Jain Richa Jain Sourabh Jain

It is a microcontrolled instrument which uses a probe/sensor for detection and counting of microbes.

10.1007/978-1-4939-9861-6_9

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Preliminary phytochemical, pharmacognostical and physico-chemical evaluation of Cedrus deodara heartwood

Journal of Pharmacognosy and Phytochemistry (2014)

Sourabh Jain Aakanchha Jain Ankur Vaidya Dharmendra Kumar Vikas Jain

Deodar (Cedrus deodara Roxb.) is one of the most useful traditional medicinal plant in India. Each part of the Deodar tree has some medicinal property and is thus commercially exploitable. During the last five decades, apart from the chemistry of the Deodar compounds, considerable progress has been achieved regarding the biological activity and medicinal applications of Deodar. The present study was carried out to investigate morphological, microscopical, physicochemical and phytochemical screening of Cedrus deodara heartwood. Morphological studies showed the presence of various diagnostic characters. In the microscopical studies showed the presence of Collenchyma, Xylem parenchyma, Tracheids and Sclrenchyma. Ash value, extractive value and moisture content were determined for quality standard of drugs. Phytochemical investigation shows the presence of tannins, flavanoids, alkaloids, and terpenoids.

Phytochemical

Tracheid

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Potential of natural polymeric materials in pharmaceutics

Pharmacological Research - Natural Products (2024)

Sourabh Jain Aakanchha Jain Richa Jain Nagendra Singh Chauhan

Pharmaceutics

10.1016/j.prenap.2024.100014

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Decoding Artificial Intelligence in Neuroscience: Applications Beyond Diagnosis

Current Indian Science (2023)

Sagar Salave Dhwani Rana Derajram Benival Aakanchha Jain

Background: Artificial Intelligence has witnessed exponential expansion in health care applications. The article pronounces the dynamic excellence AI is achieving in the healthcare discipline of neuroscience. Objective: The paper highlights basic concepts of AI and acmes the interdisciplinary collaboration of Computational neuroscience, Cognitive science, and AI. Also, the article draws out important findings related to AI in neuroscience amongst its diverse application in the various disciplines. An ephemeral overview of applications of AI-based constructs in neurological disorders namely Neuroinflammation, Schizophrenia, Parkinson’s disease, Epilepsy, Autism spectrum disorder, Alzheimer’s disease, Brain tumor and Anesthesiology has been demonstrated in the present work. Methods: The method includes the collection of data from different search engines like google Scholar, PubMed, ScienceDirect, SciFinder, etc. to get coverage of relevant literature for accumulating appropriate information regarding AI, neuroscience, and their linkages. Results: These considerations are made to expand the existing literature on the progressing role of AI in the management of neurological disorders. Conclusion: The exponential expansion in the development of AI-based systems might aid in addressing the prevailing limitations in the domain of neurological disorders and neuroscience.

Computational neuroscience

Systems neuroscience

Excellence

10.2174/2210299x01666230223104508

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