Anna Cecília Queiroz de M

Universidade Federal do Rio Grande do Norte

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Kênio Costa de Lima

Universidade Federal do Rio Grande do Norte

Vanessa Teixeira de Lima O

Universidade Federal do Rio Grande do Norte

Débora Azevedo N

Universidade Federal do Rio Grande do Norte

Lucía de Fátima Campos P

Universidade Federal do Rio Grande do Norte

Lorena dos Santos T

Universidade Federal do Rio Grande do Norte

Maria das Graças Almeida

Universidade Federal do Rio Grande do Norte

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Universidade Federal do Rio Grande do Norte

Universidade Federal do Rio Grande

Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

Ensco (United States)

Nortel (Canada)

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Centro de Estudos e Pesquisa em Saúde Coletiva

Faculdades Guarulhos

Sociedade Portuguesa de Cardiologia

Associação Brasileira de Saúde Coletiva

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ALTERACIONES EN EL METABOLISMO DEL ZINC RELACIONADAS A LA EDAD

Revista chilena de nutrición (2008)

Anna Cecília Queiroz de M Maria das Graças Almeida Vanessa Teixeira de Lima O Débora Azevedo N Kênio Costa de Lima

Although many studies point to alterations in the organic concentrations of zinc in elderly patients, the mechanisms by which aging might cause changes in the metabolism of this nutrient remain unclear. Thus, we assessed the changes in plasma zinc, zinc binding capacity to plasma protein (ZnBCPP) and saturation index (SI), comparing elderly individuals and young adults. The zinc analyses were performed by atomic absorption spectrophotometry. A statistically significant difference (p < 0.001) was found between the two groups in relation to plasma zinc and SI, but the ZnBCPP did not differ between the younger and older subjects. In agreement with this result, it was shown in the young group that 76% (R 2 = 0.760) of the ZnBCPP variations are explained by the variations in plasma zinc and SI.In the elderly group this measure decreased to 30.5% (R 2 = 0.305).We conclude, therefore, that aging may be a factor associated to changes in control mechanisms and in zinc homeostasis, and could even alter ZnBCPP response patterns and other zinc-related indicators of nutritional status.

10.4067/s0717-75182008000200005

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