J. E. Thompson

Texas Tech University

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

E. B. Dumbroff

Hebrew University of Jerusalem

T. S. Sudarshan

University of South Carolina

Raymond L. Legge

University of Waterloo

J. Kruuv

University of Waterloo

Bart M. Ballard

Texas A&M University – Kingsville

M. Cavaglià

Missouri University of Science and Technology

R. De Pietri

Istituto Nazionale di Fisica Nucleare, Sezione di Milano Bicocca

P. Cerdá–Durán

Universitat de València

B. L. Swinkels

National Institute for Subatomic Physics

J. Steinlechner

University of Glasgow

Cooperative Institutions

Centre National de la Recherche Scientifique

549

California Institute of Technology

489

Max Planck Institute for Gravitational Physics

274

The University of Tokyo

253

Massachusetts Institute of Technology

244

LIGO Scientific Collaboration

240

Cardiff University

240

Université Paris Cité

225

Institut National de Physique Nucléaire et de Physique des Particules

200

National Institute for Subatomic Physics

189

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

Pre-Breakdown and Breakdown Phenomena along Pmma Surfaces in Vacuum and Nitrogen Gas Stressed by 60 Hz Voltages

IEEE Transactions on Electrical Insulation (1984)

James A. Lewis T. S. Sudarshan J. E. Thompson D. Lee Roger A. Dougal

Predischarge current and breakdown measurements of solid Plexiglas速 (PMMA) insulators in vacuum and nitrogen gas gaps, excited by 60 Hz ac voltages, are reported. Results show that for bridged vacuum gaps, the predischarge current is in the form of pulses. In addition to electron emission from the cathode, secondary emission from the insulator surface is postulated to play a significant role in determining the characteristics of the current pulses. It is reported that for bridged nitrogen filled gaps no partial discharges prior to breakdown were noted, except for the case of introduced artificial voids. Insulating spacers in the form of circular cylinders and conical frustrums of different angles have been studied. The breakdown characteristics are found to depend strongly on the shape of the insulating spacer and also on the surface condition. For any given gas pressure, the breakdown strength was found to decrease with decreasing angle of the cone frustrum at its base. A rough insulator surface exhibited considerable discharge track resistance compared to a smooth surface. For cylindrical spacers, the predischarge and breakdown characteristics are found to be strongly influenced by the shape and position of the introduced voids. The effect of gas pressure on the pre-discharge and breakdown characteristics are reported.

Electrical breakdown

Gas pressure

Nitrogen gas

Arc flash

Sulfur hexafluoride

Secondary emission

10.1109/tei.1984.298822

Cite

Citations (16)

CCDC 2204985: Experimental Crystal Structure Determination

The Cambridge Structural Database (2023)

Siavash Shahbazi Nia M. Anwar Hossain Guangchen Ji Sravan K. Jonnalagadda Samuel Obeng

An entry from the Cambridge Structural Database, the world’s repository for small molecule crystal structures. The entry contains experimental data from a crystal diffraction study. The deposited dataset for this entry is freely available from the CCDC and typically includes 3D coordinates, cell parameters, space group, experimental conditions and quality measures.

10.5517/ccdc.csd.cc2d0gkg

Cite

Citations (0)

Aging of Polyethylene for Cable Insulation

IEEE Transactions on Electrical Insulation (1987)

S. Grzybowski Aleksandra Rakowska J. E. Thompson

Experimental investigations have been carried out on specimens mens of polyethylene sheets and foil. Polyethylene was subjected to different types of aging which produced a variety of internal degenerative effects. Subsequently, various electrical properties of aged and unaged specimens were measured. Associated structural changes in the polyethylene were determined by means of infrared spectrophotometric analyses. The relationships between the structural and electrical changes were determined.

Cross-linked polyethylene

10.1109/tei.1987.298934

Cite

Citations (10)

Characterization of a Nonselective Opioid Receptor Functional Antagonist: Implications for Development as a Novel Opioid Dependence Medication

ACS Pharmacology & Translational Science (2024)

Siavash Shahbazi Nia Yuma T. Ortiz Julio D. Zuarth Gonzalez Leila G. Shamir Kofi Frimpong-Manson

Opioids represent the most extensive category of abused substances in the United States, and the number of fatalities caused by these drugs exceeds those associated with all other drug overdoses combined. The administration of naltrexone, a potent pan-opioid receptor antagonist, to an individual dependent on opioids can trigger opioid withdrawal and induce severe side effects. There is a pressing demand for opioid antagonists free of opioid withdrawal effects. In our laboratory, we have identified a compound with affinity to mu, delta, and kappa opioid receptors in the range of 150–250 nM. This blood–brain barrier (BBB)-permeant compound was metabolically stable in vitro and in vivo. Our in vivo work demonstrated that 1–10 mg/kg intraperitoneal administration of our compound produces moderate efficacy in antagonizing morphine-induced antiallodynia effects in the chemotherapy-induced peripheral neuropathy (CIPN) model. The treatment was well-tolerated and did not cause behavioral changes. We have observed a fast elimination rate of this metabolically stable molecule. Furthermore, no organ toxicity was observed during the chronic administration of the compound over a 14-day period. Overall, we report a novel functional opioid antagonist holds promise for developing an opioid withdrawal therapeutic.

Opioid antagonist

10.1021/acsptsci.3c00262

Cite

Citations (0)

<title>An Infrared Radiation Detector For Laser Diagnostics</title>

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (1975)

J. E. Thompson

A liquid biased, liquid crystal, infrared radiation detector has been devised for the purpose of determining the time integrated output spectrum and power spatial distribution of infrared radiation. The device has been specifically used to measure the spectrum and spaital power distribution of the output of a quasi-cw carbon monoxide gas laser. The detector recording medium is composed of thin mylar coated with temperature sensitive, encapsulated, cholesteric, liquid crystals and energy absorbing black paint. A uniform spatial color distribution of the liquid crystals is established and maintained by immersion in a controlled temperature liquid bath. The resulting uniform color distribution is modified, at various spatial points, by the addition of laser energy obtained either indirectly from the laser output coupler to yield the spatial dependence of the near or far field laser output or from a spectrometer output to yield the spectrum of the laser output. The addition of less than 15 mJ/cm2 of incident energy is adequate to modify the color distribution. The uniformity and precise control of the liquid crystal temperature and hence color, by the use of a liquid bath, makes it possible to compare colors, and hence laser output powers, at various spatial points. This permits the mapping of the laser near field output spatial distribution and the distribution of the laser spectrum with greater sensitivity than has been possible with more conventional tech, niques. Results showing the near field energy distribution and output spectrum of a supersonic flow, electric discharge CO laser obtained using the detection technique will be presented.

10.1117/12.954561

Cite

Citations (0)

Cloned manganese superoxide dismutase reduces oxidative stress in Escherichia coli and Anacystis nidulans.

Proceedings of the National Academy of Sciences (1990)

Margaret Y. Gruber Bernard R. Glick J. E. Thompson

The Mn superoxide dismutase gene of Escherichia coli was subcloned into the E. coli-Anacystis nidulans shuttle vector pSG111 to make the plasmid pMYG1. Transformation of E. coli HB101 with pMYG1 resulted in a 6-fold increase in superoxide dismutase activity. There was also induction of Mn superoxide dismutase in the transformants upon exposure to paraquat, as evidenced by dramatically increased levels of the Mn superoxide dismutase polypeptide in cytoplasmic extracts and a 16-fold further increase in superoxide dismutase activity. As well, the E. coli transformants showed resistance to paraquat-mediated inhibition of growth. Anacystis nidulans, a cyanobacterium that has no detectable Mn superoxide dismutase and is, consequently, very sensitive to oxidative stress, was also transformed with pMYG1. The transformants had detectable levels of Mn superoxide dismutase protein and showed resistance to paraquat-mediated inhibition of growth and photobleaching of pigments. Paraquat is known to promote formation of the superoxide radical anion, O2-., and thus the data have been interpreted as indicating that the cloned Mn superoxide dismutase provides protection in both E. coli and A. nidulans against damage attributable to O2-..

Dismutase

10.1073/pnas.87.7.2608

Cite

Citations (28)

In vitro simulation of senescence-related membrane damage by ozone-induced lipid peroxidation

Nature (1980)

K. Peter Pauls J. E. Thompson

Cotyledon

Senescence

Membrane Lipids

10.1038/283504a0

Cite