Zhuye Shang

Research Field

We report the development of a red-emitting fluorescence probe (XDS) for hydrogen sulfide (H2S) detection in biosystems, real-world food samples, and application of this probe for monitoring of H2S production during food spoilage. The XDS probe is developed by coupling of coumarin derivative to rhodanic-CN through a H2S responsive CC bond. Remarkable fluorescence quenching of XDS is observed as a result of the response to H2S. Semi-quantitative detection of H2S in three real-world water and two beer samples and monitoring of H2S production during food spoilage in real-time by "naked-eye" and smartphone colorimetric analysis are then achieved using XDS as the probe. Moreover, XDS is low toxicity, allowing it being used for visualizing endogenous and exogenous H2S in vivo in a mouse model. It is expected that the successful development of XDS could provide an effective tool for investigating the roles of H2S in biomedical system and for future food safety evaluation.

Naked eye

10.1016/j.foodchem.2023.136701

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Citations (55)

Phenothiazine-based “turn-on” fluorescent probe for the detection of hydrazine in water, soil, plant and food samples

New Journal of Chemistry (2024)

Wen‐Qian Zhang Zhuye Shang Zhiqiang Zhang Qingtao Meng

As a common chemical raw material, even a small amount of hydrazine (N 2 H 4 ) residue can cause irreversible damage to the environment.

Hydrazine (antidepressant)

Turn (biochemistry)

10.1039/d4nj04488f

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Citations (0)

A near-infrared fluorescent probe for rapid and on-site detection of sulfur dioxide derivative in biological, food and environmental systems

Journal of Hazardous Materials (2023)

Zhuye Shang Miaomiao Wu Qingtao Meng Yang Jiao Zhiqiang Zhang

Emission of toxic gaseous sulfur dioxide (SO

Moiety

Industrial wastewater treatment

Bisulfite

Benzothiazole

10.1016/j.jhazmat.2023.133165

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Citations (27)

Triphenylamine-embedded copper(ii) complex as a “turn-on” fluorescent probe for the detection of nitric oxide in living animals

Analytical Methods (2022)

Zhuye Shang Li Shu Jianhua Liu Qingtao Meng Yue Wang

A triphenylamine-copper( ii )-based fluorescence probe (NZ-Cu 2+ ) has been developed for the detection of NO in vivo .

Triphenylamine

CLs upper limits

10.1039/d2ay01629j

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Citations (6)

A dual-response triphenylamine-based fluorescent probe for selective sensing of copper(II) and nitric oxide in live cells

Journal of Molecular Structure (2022)

Li Shu Zhuye Shang Jing Li Yan Gao Wanli Bi

Triphenylamine

Photoinduced electron transfer

10.1016/j.molstruc.2022.134032

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Citations (6)

A red-emission fluorescence probe based on 1,4-addition reaction mechanism for the detection of biothiols in vitro and in vivo

Analytical Sciences (2021)

Yaoyun Hu Zhuye Shang Pengli Gu Guangjie He Run Zhang

In this work, a new fluorescence probe (DC) with a donor-π-acceptor (D-π-A) structure was designed and synthesized for the detection of three kinds of biothiols (Cys, Hcy and GSH) in live cells and organisms. DC displayed an intense red-emission centered at 625 nm. In the presence of biothiols, the nucleophilic addition reaction between the C=C double bond of DC and the sulfhydryl group (-SH) of biothiols occurred, resulting in obvious fluorescence quenching responses. DC exhibited high selectivity towards biothiols over other common bioactive species with low detection limits (0.26, 0.43, and 0.44 µM for Cys, Hcy and GSH, respectively). In addition, DC displayed a rapid response to biothiols within 4 min. The applications of DC in biothiols detection and imaging were then successfully demonstrated for the real-time monitoring of endogenous and exogenous biothiols in live cells and live animals.

Nucleophilic Addition

Acceptor

10.2116/analsci.21p177

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Bifunctional near-infrared fluorescent probe for the selective detection of bisulfite and hypochlorous acid in food, water samples and in vivo

Analytica Chimica Acta (2023)

Zhuye Shang Qingtao Meng Run Zhang Zhiqiang Zhang

Hypochlorous acid

Bisulfite

Hypochlorite

10.1016/j.aca.2023.341783