E López

National Institute on Aging

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Co-Authors

G Piédrola

Hospital Universitario Virgen de las Nieves

C. Milet

University of Mendoza

Rafael Bárcena Marugán

Hospital Universitario Ramón y Cajal

Javier Nuño Vázquez-Garza

Hospital Universitario Ramón y Cajal

Javier Moreno García

Hospital Universitario Ramón y Cajal

Elena Nieto

Hospital Universitario Nuestra Señora de Candelaria

Eduardo Albéniz

Universidad Publica de Navarra

Héctor F. Escobar‐Morreale

Universidad de Alcalá

G Moraleda Garcia

Universidad de Alcalá

Huaibin Cai

National Institute on Aging

Cooperative Institutions

Hospital Universitario Ramón y Cajal

Harvard University

National Institutes of Health

Universidad de Alcalá

Instituto Cajal

Instituto Ramón y Cajal de Investigación Sanitaria

Center for Cancer Research

Massachusetts General Hospital

Instituto de Salud Carlos III

National Institute on Aging

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Changes in dog's coronary circulation by hypothalamic stimulation.

PubMed (1962)

J Alanís E López Odrick R. Rosas

Circulation (fluid dynamics)

Coronary circulation

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Citations (10)

Impulse oscillometry reference values and bronchodilator response in three- to five-year old children living at high altitude

DOAJ (DOAJ: Directory of Open Access Journals) (2019)

Elida Duenas‐Meza E Correa E López Morales Concepción Jc Aguirre-Franco CE

Impulse response

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Citations (15)

[Hypoactivity of the thyroid gland in rabbits immunized against bovine thyrotropic hormone].

PubMed (1969)

F Lachiver Fontaine Ya E López Adriana Martin

Hypoactivity

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Citations (2)

A Monoclonal Antibody Against the Extracellular Domain of Mouse and Human Epithelial V-like Antigen 1 Reveals a Restricted Expression Pattern Among CD4- CD8- Thymocytes

Monoclonal Antibodies in Immunodiagnosis and Immunotherapy (2014)

Nahir Garabatos Jesús Blanco César Fandos E López Pere Santamaría

Expression of transcripts for the homotypic adhesion protein epithelial V-like antigen 1 (EVA1), also known as myelin protein zero like-2 (Mpzl2), is known to be present in thymic stromal cells. However, protein expression within different thymic subsets, stromal and/or lymphoid, has not been characterized due a lack of specific reagents. To address this, we generated a hybridoma (G9P3-1) secreting a monoclonal antibody (G9P3-1Mab), reactive against both human and mouse EVA1. The G9P3-1Mab was generated by immunizing Mpzl2-deficient gene-targeted mice with the extracellular domain of EVA1, followed by a conventional hybridoma fusion protocol, illustrating the feasibility of using gene-targeted mice to generate monoclonal antibodies with multiple species cross-reactivity. We confirmed expression of EVA1 on cortical and medullary epithelial cell subsets and revealed a restricted pattern of expression on CD4- CD8- double negative (DN) cell subsets, with the highest level of expression on DN3 (CD44lowCD25+) thymocytes. G9P3-1MAb is a valuable reagent to study thymic T cell development and is likely useful for the analysis of pathological conditions affecting thymopoiesis, such as thymic involution caused by stress or aging.

10.1089/mab.2014.0030

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Citations (4)

Clinical features of adrenal insufficiency in patients with acquired immunodeficiency syndrome

Clinical Endocrinology (1996)

G Piédrola José L. Casado E López Ana Moreno María Jesús Pérez‐Elías

Summary OBJECTIVE Adrenal insufficiency (Al) is a well known complication of AIDS. However, the clinical and biochemical features of Al in HIV infected patients have not been extensively studied. DESIGN A restrospective clinical study. PATIENTS We reviewed clinical records of 74 AIDS patients with clinical and/or biochemical indications of Al who underwent Synacthen testing in order to determine adrenocortical function during a 5‐year period. MEASUREMENTS AI was diagnosed when Cortisol levels failed to rise above 496 nmol/l at any time during the test. Cortisol was measured by RIA. RESULTS Sixteen patients (22%) were diagnosed with Al. Most were young males and all of them had a known risk factor, principally I.v. drug users. The main complaint was fatigue. Hyponatraemia or hyperkalaemia were uncommon. All of them were severely immuno‐suppressed, with AIDS‐defining conditions from at least 6 months before the diagnosis of Al, and had been diagnosed with at least one disease that has been reported to produce Al in AIDS patients. Survival was poor. Thirteen of these patients (81%) died within 6 months. Basal cortisol levels were lower than 275 nmol/l in 75% of patients with Al but in only 2% of the group of 58 patients who had normal adrenal responses to Synacthen. CONCLUSIONS Adrenal insufficiency features in AIDS patients with advanced disease, without specific findings and with a history of previous opportunistic diseases. Basal cortisol values at 0830 h lower than 275 nmol/l are highly suggestive of adrenal insufficiency in patients with AIDS.

Basal (medicine)

Adrenocortical Insufficiency

Medical record

10.1111/j.1365-2265.1996.tb02066.x

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Citations (63)

Hormonal Studies in Cushing's Syndrome During Petrosal Sinus Catheterization: Part I: Existence of Multihormonal Gradients

Hormone and Metabolic Research (1997)

E López G Piédrola Héctor F. Escobar‐Morreale Joaquín Serrano O González

Inferior petrosal sinus

10.1055/s-2007-979054

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Citations (0)

Hormonal Studies in Cushing's Syndrome During Petrosal Sinus Catheterization: Part II: Absence of Relationship Between Intestinal Vasoactive Peptide and Prolactin

Hormone and Metabolic Research (1997)

E López Fernando Pazos José Antonio Balsa G Piédrola Héctor F. Escobar‐Morreale

Inferior petrosal sinus

Vasoactive

10.1055/s-2007-979066

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Citations (0)

Prophylaxis of recurrent hepatitis B virus by vaccination after liver transplant: preliminary results

Transplantation Proceedings (2003)

Eduardo Albéniz Rafael Bárcena Marugán Elena Nieto Elisa Carrera Alonso Mercé García-Gónzalez

Hepatitis B

Liver disease

10.1016/s0041-1345(03)00633-x

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Citations (30)

Framework for Interface to Network Security Functions

Diego López E López Linda Dunbar John Strassner Rahul Kumar

This document describes the framework for Interface to Network Security Functions (I2NSF) and defines a reference model (including major functional components) for I2NSF. Network Security Functions (NSFs) are packet-processing engines that inspect and optionally modify packets traversing networks, either directly or in the context of sessions to which the packet is associated.

Interface (matter)

10.17487/rfc8329

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Citations (22)

[Diagnosis & treatment of adrenal cortex insufficiency].

PubMed (1956)

F Donoso E López

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Citations (0)