Adriana Polańska

Poznan University of Medical Sciences

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Aleksandra Dańczak‐Pazdrowska

Poznan University of Medical Sciences

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Ryszard Żaba

Poznan University of Medical Sciences

Zygmunt Adamski

Poznan University of Medical Sciences

Dorota Jenerowicz

Poznan University of Medical Sciences

Agnieszka Osmola‐Mańkowska

Poznan University of Medical Sciences

Monika Bowszyc‐Dmochowska

Poznan University of Medical Sciences

Wojciech Silny

Poznan University of Medical Sciences

Karolina Olek‐Hrab

Poznan University of Medical Sciences

Adam Reich

Rzeszów University

Magdalena Czarnecka‐Operacz

Poznan University of Medical Sciences

Cooperative Institutions

Physician’s Hair Institute

149

Tehran University of Medical Sciences

148

University of Rochester

144

Ahvaz Jundishapur University of Medical Sciences

143

Poznan University of Medical Sciences

105

Medical University of Warsaw

Nicolaus Copernicus University

Polska Grupa Górnicza (Poland)

Collegium Medicum in Bydgoszcz

Temple University

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High-Frequency Ultrasonography and Evaporimetry in Non-invasive Evaluation of the Nail Unit

Frontiers in Medicine (2021)

Marta Szymoniak‐Lipska Adriana Polańska Dorota Jenerowicz Adam Lipski Ryszard Żaba

Background: The nail unit (NU) is a complex structure that performs a number of functions, including protection, defense, manipulation, and palpation. Non-invasive research methods can facilitate the recognition of NU structure and function. Evaporimetry and HF-USG due to their availability of equipment and low research costs seem to be particularly noteworthy, but so far have been assessed to a limited extent. The aim of the presented study was to check the usefulness of TOWL and HF-USG in examination of NU. Materials and Methods: A total of 58 volunteers aged 25–65 years (mean age: 41 ± 10.16 years) were qualified for the study. The subjects did not present symptoms of clinically evident onychopathy and did not suffer from any dermatoses associated with lesions occurring within the NU. Additionally, the patients did not suffer from systemic diseases that could affect NU (including heart, lung, and endocrine diseases). In all volunteers, the measurement of TOWL and 20 MHz ultrasonography [high-frequency ultrasonography (HF-USG)] with the special emphasis on determination of nail plate thickness were performed. Results: Analysis of 464 HF-USG images revealed that the nail plate presented as two hyperechoic, parallel streaks (railway sign) with a linear hypoechoic middle layer between them. Matrix was visualized as a hypoechoic structure with blurred boundaries, mostly within the fourth and fifth fingers and more often in women. We found statistically significant correlations between the type of a finger and the thickness of the nail plate both in the entire study group and taking into account gender. In the dominant hand, the results were r = −0.341; p < 0.001; r = −0.417, p < 0.001; and r = 0.337; p = 0.001 (for the whole group, for women, and for men, respectively). In the non-dominant hand, the results were r = −0.465; p < 0.001; r = −0.493, p < 0.01; and r = −0.503; p < 0.01 (for the whole group, for women, and for men, respectively). There were statistically significant differences in the thickness of the nail plates of the corresponding types of fingers between female and male NUs. Statistically significant correlations were found between the type of a finger and the TOWL value in the whole group and taking into account gender ( p < 0.05), except for the non-dominant hand in men. There were no statistically significant differences in the TOWL values of the corresponding types of fingers between male and female NUs ( p > 0.05). There was no statistically significant correlation between the TOWL value and the nail plate thickness in any of the tested NUs, apart from the one statistically significant correlation in nd5 ( r = 0.390, p = 0.021). Conclusions: To sum up, non-invasive methods, such as HF-USG and TOWL, enable assessment of the NU and are useful in examination of its structure and function. HF-USG shows characteristic elements of NUs that can be distinguished because of differences in their echogenicity. The thickness of the nail plate and TOWL depend on the type of finger, and show a relationship with gender.

Palpation

10.3389/fmed.2021.686470

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Controversy around the morphea

Advances in Dermatology and Allergology (2021)

Aleksandra Dańczak‐Pazdrowska Paulina Cieplewicz Ryszard Żaba Zygmunt Adamski Adriana Polańska

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Dańczak-Pazdrowska A, Cieplewicz P, Żaba R, Adamski Z, Polańska A. Controversy around the morphea. Postępy Dermatologii i Alergologii/Advances in Dermatology and Allergology. 2021. doi:10.5114/ada.2021.106242. APA Dańczak-Pazdrowska, A., Cieplewicz, P., Żaba, R., Adamski, Z., & Polańska, A. (2021). Controversy around the morphea. Postępy Dermatologii i Alergologii/Advances in Dermatology and Allergology. https://doi.org/10.5114/ada.2021.106242 Chicago Dańczak-Pazdrowska, Aleksandra, Paulina Cieplewicz, Ryszard Żaba, Zygmunt Adamski, and Adriana Polańska. 2021. "Controversy around the morphea". Postępy Dermatologii i Alergologii/Advances in Dermatology and Allergology. doi:10.5114/ada.2021.106242. Harvard Dańczak-Pazdrowska, A., Cieplewicz, P., Żaba, R., Adamski, Z., and Polańska, A. (2021). Controversy around the morphea. Postępy Dermatologii i Alergologii/Advances in Dermatology and Allergology. https://doi.org/10.5114/ada.2021.106242 MLA Dańczak-Pazdrowska, Aleksandra et al. "Controversy around the morphea." Postępy Dermatologii i Alergologii/Advances in Dermatology and Allergology, 2021. doi:10.5114/ada.2021.106242. Vancouver Dańczak-Pazdrowska A, Cieplewicz P, Żaba R, Adamski Z, Polańska A. Controversy around the morphea. Postępy Dermatologii i Alergologii/Advances in Dermatology and Allergology. 2021. doi:10.5114/ada.2021.106242.

Morphea

Eosinophilic fasciitis

Sclerodactyly

Scleroderma (fungus)

Localized Scleroderma

10.5114/ada.2021.106242

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Citations (7)

Comparison between high‐frequency ultrasonography (Dermascan C, version 3) and histopathology in atopic dermatitis

Skin Research and Technology (2013)

Adriana Polańska Aleksandra Dańczak‐Pazdrowska Wojciech Silny Aldona Woźniak Konstantin Maksin

Background The main purpose of this study was the exact comparison of B‐scan images obtained from 16 patients suffering from AD with histological. Methods Sixteen patients diagnosed with AD aged between 14 and 57 years, were chosen for the study. In all patients before the introduction of proper treatment regimen, the high frequency skin ultrasonography (Derma Scan Cortex Technology, version 3, Hadsund, Germany) has been performed and then a 5 mm wide punch biopsies have been taken from the area of scanned lesions. Control group consisted of 15 healthy individuals without any signs of atopic and chronic diseases. Results There was 7.8 ± 0.4% mean skin echogenicity from lesional antecubital skin in AD patients (min value 7.2%, max value 8.5%). The skin hypoechoic band was detected in fifteen out of sixteen patients (93.7%). There were statistically significant correlations between the hypoechoic band thickness and the following parameters: degree of epidermal hyperplasia, the degree of epidermal hyperkeratosis, the degree of parakeratosis and the degree of spongiosis as well as the intensity of inflammatory infiltrates. Skin echogenicity strongly correlated negatively with the intensity of inflammatory infiltrates. Conclusion On the basis of analysis of 16 specimens we can conclude that all pathological changes of AD influence ultrasound image and in addition, the USG picture depends on the phase of disease process.

Echogenicity

Parakeratosis

Spongiosis

Histopathology

10.1111/srt.12064

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Citations (54)

Wplyw 1-okten-3-olu na proces skladania jaj przez samice wolka zbozowego [Sitophilus granarius L.]

Progress in Plant Protection (2001)

J. Nawrot Adriana Polańska E. Wąsowicz

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Demodicosis in humans as a current problem in dermatology and ophthalmology

Journal of Face Aesthetics (2020)

Sara Królik Agnieszka Muth Adriana Polańska Ryszard Żaba Zygmunt Adamski

Introduction. Human Demodex mites (Demodex folliculorum and Demodex brevis) are ectoparasites living inside the sebaceous glands and hair follicles. In most people, their presence is of no consequence. However, several conditions or various external factors might contribute to pathological Demodex infestation resulting in demodicosis. Many different cutaneous diseases can resemble demodicosis leading to misdiagnosis.Aim. This paper aims to present information about demodicosis and provides a clear clinical portrait of demodicosis in order to distinguish it from other mimicking inflammatory dermatoses. Material and Methods. The literature search was conducted in the English and Polish language via the PubMed database and Main Medical Library. The articles regarding Demodex infestation were selected. Results. There is some evidence about the role of Demodex in the development of rosacea, blepharitis and clinical correlation between them.Conclusions. More attention should be drawn to Demodex as it plays a significant role in the development of various clinical entities in both dermatology and ophthalmology.

Demodicosis

Demodex folliculorum

Blepharitis

Dandruff

10.20883/jofa.36

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Citations (1)

Environmental factors and allergic diseases.

PubMed (2012)

Dorota Jenerowicz Wojciech Silny Aleksandra Dańczak‐Pazdrowska Adriana Polańska Agnieszka Osmola‐Mańkowska

An objective of this article is a review of contemporary knowledge on various environmental factors, that influence prevalence and course of allergic diseases, like asthma, allergic rhinitis, atopic dermatitis and also contact dermatitis. Surrounding climate may directly influence each patient, but also determines type of flora and fauna within particular geographical regions and thus affects sources of airborne and food allergens. Epidemiological studies suggest that there is a strong relationship between air pollution and development and exacerbation of asthma and other allergic diseases--main attention has been concentrated on gaseous materials such as ozone (O(3)) and nitrogen dioxide (NO(2)), as well as particulate matter (PM), generated by car traffic and industry. Diesel exhaust particulate (DEP) has the ability to bind proteins and may serve as a potential carrier of allergens, penetrating deep into respiratory tract. Among the most extensively studied environmental factors influencing allergy are airborne allergens: dust mites, pollens, fungi and animal dander. Foods may elicit both true IgE-mediated allergy and also various non-immunological reactions, associated with direct release of mediators or toxic activity. It has been estimated, that over 85,000 chemicals are recognized in the human environment and they may act as contact allergens or irritants, causing allergic or non-allergic contact dermatitis. Among them metals, fragrances, preservatives, botanicals and paraphenylenediamine are considered as the most significant. Infections have always been associated with etiopathogenesis of allergic diseases and they may contribute to exacerbation of their course.

Dander

Airborne allergen

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Citations (133)

[Histiocytosis X--report of 3 cases with different types of lung changes].

PubMed (1997)

Dariusz Jastrzębski Jerzy Kozielski Dariusz Ziora Adriana Polańska Piotr Grzanka

Three cases of histiocytosis X were described. Diagnosis was confirmed with histological examination of the lung taken during pleuroscopy in 2 cases and--with typical HRCT lung scan in 1 case.

Histiocytosis X

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Original paper Estimation of vancomycin MIC for Staphylococcus aureus in patients treated in the Chair and Department of Dermatology, Poznan University of Medical Sciences

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii (2011)

Hanna Tomczak Aleksandra Dańczak‐Pazdrowska Anna Horla Monika Duś-Żuchowska Wioleta Błażejewska

Introduction: Staphylococcus aureus (S. aureus) represents a significant aetiological factor in infections of skin and soft tissues. Resistance to vancomycin is very rare. In recent years the MIC creep phenomenon has been noted. At present, it is suggested that S. aureus strains with vancomycin minimal inhibitory concentration (MIC) at a level > 1 μg/ml poorly respond to treatment. Aim: The study was aimed to compare MIC evaluated in the automatic system of Vitek with the real MIC of van- comycin for S. aureus strains isolated from patients treated in the Department of Dermatology, Poznan University of Medical Sciences. Material and methods: Material for the studies involved 80 smears sampled from dermal lesions in patients diag- nosed and treated in the Department of Dermatology, Poznan University of Medical Sciences in Poznan between May 2008 and December 2010. Results: Methicillin-sensitive S. aureus strains (MSSA) were isolated in 76 cases (95%), while methicillin-resistant S. aureus (MRSA) - in 4 cases (5%). Using the automatic Vitek technique in 72 cases (90%), the obtained vancomycin MIC for S. aureus amounted to ≤ 0.5 μg/ml, in 5 cases to 1 μg/ml and in 3 cases to 2 μg/ml. Using Etest technique, the real MIC amounted in one case to 0.5 μg/ml, in 1 case to 0.75 μg/ml, in 1 case to 1 μg/ml, in 19 cases to 1.5 μg/ml and in 58 cases to 2.0 μg/ml. Conclusions: Due to the MIC creep phenomenon and extensive diversities obtained in estimates of S. aureus resis- tance to vancomycin, the authors suggest estimating the real MIC.

Etest

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Sprawozdanie z konferencji Top Masters in Dermatology Rzeszów, 12–14 wrzeœnia 2019 r.

DOAJ (DOAJ: Directory of Open Access Journals) (2019)

Marta Szymoniak‐Lipska Aleksandra Dańczak‐Pazdrowska Adriana Polańska

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Microbiological analysis of acute infections of the nail fold on the basis of bait thread test

Advances in Dermatology and Allergology (2017)

Hanna Tomczak Aleksandra Dańczak‐Pazdrowska Adriana Polańska Agnieszka Osmola‐Mańkowska Jakub Pazdrowski

An acute infection of the nail fold, called paronychia, is a common clinical problem. The basis for the implementation of the treatment is the result of microbiological examination. Due to the rapid and painful course of infection, usually an empirical antimicrobial treatment prior to obtaining microbiological test results is introduced.The microbial analysis of acute infections of the nail fold.The study included 32 tests conducted on 31 patients of the Department of Dermatology. Microbiological analysis was performed with the use of the so-called bait thread test.In 73% of analyzed cases microbiological examination revealed mixed microbiological flora. Most cultured microorganisms were: Enterococcus faecalis (14%), Staphylococcus aureus (12%), Candida albicans (9%), Enterobacter cloacae (8%), and Klebsiella pneumoniae (7%). Most cultured bacteria belonged to the families or genera of Enterobacteriaceae (36%), other cultured bacteria were staphylococci (26%), enterococci (16%), Candida species (14%), and Gram-negative non-fermenting bacilli (8%).The acute infection of the nail fold in the vast majority of cases is caused by mixed bacterial flora. A profile of isolated microorganisms suggests that the cause of the infection can be associated with neglect of hygiene. Fluoroquinolone and fusidic acid are recommended as the empirical therapy. Microbiological examination is the basis for the appropriate final treatment.

10.5114/ada.2017.67072

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Citations (9)