Patrick M. Mehl

United States Department of State

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P. Boutron

Institut Néel

Otto C. Wilson

Catholic University of America

Yud-Ren Chen

United States Department of Agriculture

Christopher P. McAndrew

Catholic University of America

Kevin Chao

Northwestern University

Moon S. Kim

United States Department of Agriculture

Gregory M. Fahy

21st Century Medicine (United States)

Bijan S. Khirabadi

United States Army Institute of Surgical Research

James Keeven

University of America

Joseph Zischkau

Carnegie Mellon University

Cooperative Institutions

University of America

Catholic University of America

National Institutes of Health

American Red Cross

Naval Medical Research Command

National Cancer Institute

Center for Cancer Research

Agricultural Research Service

United States Department of Agriculture

Dickinson College

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Enhanced cell survival and diminished apoptotic response to simulated ischemia–reperfusion in H9c2 cells by magnetic field preconditioning

APOPTOSIS (2012)

Mani V. Kurian Lanette Hamilton James Keeven Patrick M. Mehl J. Michael Mullins

10.1007/s10495-012-0747-9

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Citations (12)

Solubility and glass transition in the system α-D-trehalose/water

Journal of thermal analysis (1997)

Patrick M. Mehl

Precipitation of trehalose dihydrate in water is observed at room temperature for trehalose concentrations higher than 47.5%w/w. Direct observations of crystal melting in water and measures of the solution density determine the thermal variations of trehalose saturationS(T) (mM) in water: ln(S(T))=ln(0.1223)-(1330/T) withR 2 =0.9982. The glass transition (Tg) curve measured by DSC is lower at low concentrations and higher at high concentrations than previously reported.T g is also measured as a function of the cooling/warming rates. Analysis of specific heat changes atT g and associated activation energy leads to identify a most stable glassy state around the second eutectic concentration.

Supercooling

Water activity

10.1007/bf01996765

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Citations (17)

Determination of enthalpy relaxation times using traditional differential scanning calorimetry for glycerol and for propylene glycol

Thermochimica Acta (1996)

Patrick M. Mehl

Isothermal process

10.1016/0040-6031(95)02455-7

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Citations (19)

Use of hyper- and multi-spectral imaging for detection of chicken skin tumors.

2000 ASAE Annual International Meeting, Milwaukee, Wisconsin, USA, 9-12 July 2000. (2000)

Kuanglin Chao Patrick M. Mehl Y. R. Chen

Hyperspectral and multispectral imaging techniques were used to detect chicken skin tumors. Hyperspectral images of eight tumorous chickens were taken in the spectral range of 420 to 850 nm. Principal component analysis was applied to select useful wavelength bands (465, 575, 705 nm) from the tumorous chicken images. A multispectral imaging system capable of simultaneously capturing three registered images was used to image 60 tumorous and 20 normal chickens. Multispectral image analysis was performed to generate ratioed images, which were then divided into regions of interest (ROI’s) classified as either tumorous or normal by a veterinarian. Image features for each ROI (coefficient of variation, skewness, and kurtosis) were extracted for use as inputs to fuzzy classifiers. The fuzzy classifiers were able to separate normal from tumorous skin with increasing accuracies as more features were used. In particular, use of all three features gave successful detection rates of 91 and 86% for normal and tumorous tissue, respectively.

Kurtosis

Region of interest

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Citations (7)

<title>Detection of chicken skin tumors by mutlispectral imaging</title>

Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE (2001)

Kevin Chao Patrick M. Mehl Moon S. Kim Yud-Ren Chen

Hyperspectral and multispectral imaging techniques were used to detect chicken skin tumors. Hyperspectral images of eight tumorous chickens were taken in the spectral range of 420-850 nm. Principle component analysis was applied to select useful wavelength bands (465, 575, 705 nm) from the tumorous chicken images. A multispectral imaging system capable of simultaneously capturing three registered images was used to image 60 tumorous and 20 normal chickens. Multispectral image analysis was performed to generate ratioed images, which were then divided into regions of interest (ROT's) classified as either tumorous or normal by a veterinarian. Image features for each ROT (coefficient of variation, skewness and kurtosis) were extracted for use as inputs to fuzzy classifiers. The fuzzy classifiers were able to separate normal from tumorous skin with increasing accuracies as more features were used. In particular, use of all three features gave successful detection rates of 9 1 % and 86% for normal and tumorous tissue, respectively.

Kurtosis

10.1117/12.418732

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Citations (2)

Ternary system 1,2-propanediol, 2,3-butanediol and Euro-Collins solution: Glass-forming tendency and stability of the amorphous state

Cryoletters (1992)

Patrick M. Mehl

Ternary numeral system

Propanediol

2,3-Butanediol

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Citations (3)

Direct experimental dissection of devitrification in aqueous solutions of 1,3-butanediol

Cryobiology (1989)

Patrick M. Mehl

Devitrification

2,3-Butanediol

10.1016/0011-2240(89)90173-9

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Citations (1)

Glass-forming tendency and stability of the amorphous state in the aqueous solutions of linear polyalcohols with four carbons

Cryobiology (1987)

Patrick M. Mehl P. Boutron

2,3-Butanediol

Propanediol

Butanediol

1,4-Butanediol

Water of crystallization

Clathrate hydrate

10.1016/0011-2240(87)90039-3

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Citations (10)

Fictive glass-transition temperature and fragility for the phase diagram of the system fructose/water

Thermochimica Acta (1998)

Patrick M. Mehl

Vitrification

10.1016/s0040-6031(98)00538-3

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Citations (4)

Nouveaux cryoprotecteurs pour la cryopréservation des cellules par vitrification totale

Bulletin de la Société Botanique de France Actualités Botaniques (1986)

P. Boutron Patrick M. Mehl

RésuméLa tendance à former un verre et la stabilité de l'état totalement amorphe de diverses solutions dans l'eau ont été étudiées. Outre quelques cryoprotecteurs couramment utilisés pour la cryopréservation des cellules dans l'azote liquide, de nouveaux composés ont été étudiés, tous des polyalcools, seuls ou deux à deux ou en ternaires avec des monoalcools. Le plus intéressant est le 1,2-propanediol, suivi du 1,3-butanediol et peut ètre du 1, 2, 3-butanetriol. Il a été montré qu'au moins pour certaines cellules les deux premiers sont de bons cryoprotecteurs, dans les conditions classiques comme dans le cas de la vitrification totale.

Vitrification

10.1080/01811789.1986.10826788

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Citations (4)