Mohammad Ma’koseh

King Hussein Cancer Center

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i-10 index

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Khalid Halahleh

King Hussein Cancer Center

Omar Shahin

King Hussein Cancer Center

Kamal Al-Rabi

King Hussein Cancer Center

Hikmat Abdel‐Razeq

King Hussein Cancer Center

Waleed Da’na

King Hussein Cancer Center

Alaa Abufara

King Hussein Cancer Center

Abeer Yaseen

King Hussein Cancer Center

Akram Al‐Ibraheem

King Hussein Cancer Center

Anas Zayed

King Hussein Cancer Center

Mohammad Al-Rwashdeh

King Hussein Cancer Center

Cooperative Institutions

King Hussein Cancer Center

177

University of Jordan

King Hussein Medical Center

Jordan University of Science and Technology

Princess Margaret Cancer Centre

Jordan Hospital

The University of Texas MD Anderson Cancer Center

Centre Hospitalier Universitaire de Montpellier

Hospital de Especialidades

European Society for Blood and Marrow Transplantation

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Acute myeloid leukemia presenting with multiple breast and skin myeloid sarcomas: A case report

Journal of Clinical Images and Medical Case Reports (2021)

Yumna Khatib Heba Farfoura Hussam Haddad Lina Mrie Kamal AlRabie

We report a case of 63-year old female who presented to breast imaging unit with multiple bilateral breast masses. Her past history was significant for left thigh mass. Mammogram and breast ultrasound revealed multiple bilateral breast masses. Ultrasound guided true-cut biopsy from right breast mass was consistent with myeloid sarcoma. Bone marrow biopsy showed acute myeloid leukemia (FAB-M5B) evolving on the background of Chronic Myelomonocytic Leukemia (CMML).

Myeloid sarcoma

Chronic myelomonocytic leukemia

Breast ultrasound

10.52768/2766-7820/1045

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Citations (2)

High-dose chemotherapy and autotransplants for plasma cell myeloma in Jordan

Bone Marrow Transplantation (2018)

Khalid Halahleh Mohammad Ma’koseh Husam Abujazar Sameer Yaser Hani Howar

Plasma Cell Myeloma

Melphalan

10.1038/s41409-018-0201-x

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Citations (0)

Poster: ABCL-281: CALGB1002 Protocol in the Treatment of Adult Burkitt Lymphoma, Outcome, and Toxicity: A Single-Center Experience

Clinical Lymphoma Myeloma & Leukemia (2021)

Mohammad Ma’koseh Baha’ Sharaf Alaa Abufara Khalid Halahleh Rula Amarin

Single Center

Center (category theory)

10.1016/s2152-2650(21)01518-4

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The Application of the Lymphoma International Prognostic Index to Predict Venous Thromboembolic Events in Diffuse Large B-Cell Lymphoma Patients

Frontiers in Oncology (2021)

Hikmat Abdel‐Razeq Mohammad Ma’koseh Rashid Abdel-Razeq Rula Amarin Alaa Abufara

Venous thromboembolic events (VTE) are commonly encountered in patients with lymphoma. Several risk assessments models (RAM) had attempted to identify higher risk patients with varying success. The International Prognostic Index (IPI) is a clinicopathological tool developed to help predict both response to treatment and prognosis of patients with diffuse large B-cell lymphoma (DLBCL).In this study, we utilize the IPI index to identify group of patients with DLBCL at higher risk for VTE.Patients with pathologically-confirmed diagnosis of DLBCL and with image-confirmed VTE, treated and followed at our institution were included. Rates of VTE was calculated for each risk category.A total of 373 patients, median age 49 (range: 18-90) years were included. VTE were reported in 56 (15.0%) patients; 51 (91.1%) had active disease while 29 (51.8%) were ambulatory at time of VTE diagnosis. VTE rates were particularly high among patients with poor performance status (26.2%, P=0.028) and high LDH (19.0%, P=0.023). Applying the age-adjusted IPI separated patients into two risk categories; VTE were diagnosed in 9.7% in patients with "low and low-intermediate" scores compared to 19.8% in patients with "high and high-intermediate" scores, P=0.020.The original IPI and its modified versions, routinely used at diagnosis as a prognostic and predictive tool for patients with DLBCL, can also be utilized to define high risk patients for VTE; the risk of whom might be high enough to recommend thromboprophylaxis even in the ambulatory settings. More work is needed to refine and improve currently available RAMs.

International Prognostic Index

10.3389/fonc.2021.677776

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Citations (8)

ABCL-242 Definition of Bulky Disease in Early-Stage Diffuse Large B-Cell Lymphoma on Longitudinal and Axial Planes

Clinical Lymphoma Myeloma & Leukemia (2022)

Mohammad Ma’koseh Suhaib Khater Heba Farfoura Yumna Khatib Zaid Omari

B symptoms

Longitudinal Study

International Prognostic Index

10.1016/s2152-2650(22)01513-0

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Prevalence, Patterns and Predictors of Venous Thromboembolic Events in Patients Undergoing Salvage Chemotherapy and Autologous Stem Cell Transplantation for Relapsed Lymphomas

Hematology/Oncology and Stem Cell Therapy (2022)

Mohammad Ma’koseh Mohammad Al-Rwashdeh Nayef Abdel-Razeq Rozan Alfar Sarah Edaily

Autologous stem-cell transplantation

Salvage therapy

10.56875/2589-0646.1043

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Citations (1)

Survival Trends after Autologous Hematopoietic Stem Cell Transplantation for Lymphoma: A Single Center Experience over Two Decades

Clinical Lymphoma Myeloma & Leukemia (2024)

Abeer Yaseen Anas Zayed Maram Alyaqoub Waleed Da’na Omar Shahin

Center (category theory)

Single Center

Autologous stem-cell transplantation

10.1016/s2152-2650(24)01076-0

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Characteristics and Outcomes of Therapy-Related Myeloid Neoplasms (tr-MN) After Autologous Hematopoietic Stem Cell Transplantation (Auto- HCT) for Lymphoma

Clinical Lymphoma Myeloma & Leukemia (2024)

Abeer Yaseen Anas Zayed Rnad Khader Yazan Talab Waleed Da’na

10.1016/s2152-2650(24)00680-3

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Outcome and patterns of relapse in primary gastric diffuse large B cell lymphoma treated with RCHOP

Hematology (2023)

Mohammad Ma’koseh Hebah Farfoura Alaa Abufara Reem Elmusa Ahmad Hushki

Patterns and predictors of relapse in primary gastric diffuse large B cell lymphoma (DLBCL) were variably reported. Our study aims to evaluate the patterns and predictors of relapse in early-stage gastric DLBCL treated with Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisolone (RCHOP).From 2005 to 2019, the medical records of 72 patients with stage I or stage II gastric DLBCL treated with six cycles of RCHOP without radiotherapy were reviewed. Different variables were correlated with progression free survival (PFS), overall survival (OS), and local relapse free survival (LRFS).64 (88.1%) patients achieved a complete response (CR), while 8 (11.9%) had refractory disease. After CR, 9 (14%) patients relapsed; 7 (78%) relapses were loco-regional. Abnormal LDH (p = 0.028), H. pylori negative (p = 0.032) and, stage adjusted international prognostic index (sa-IPI) > 1 (p = 0.013) correlated with loco-regional failure. The 5-year PFS, OS, and LRFS were 74.8%, 75.3%, and 87.5%, respectively, after a median follow-up of 58 (range: 6-185) months. The median time to progression or relapse was 9 months (range: 5-54 months). In multivariate analysis, a sa-IPI >1 (HR: 3.56, CI: 1.35-8.8, p = 0.01) was associated with PFS while low albumin (HR: 8.85, CI: 1.09-71.4, p = 0.041) was associated with worse OS. None of the variables were associated with LRFS.Treatment of primary gastric DLBCL with RCHOP results in a high CR rate. The majority of treatment failures were loco-regional. Sa-IPI and H. pylori status may be used to identify patients who may benefit from combined modality treatment.

International Prognostic Index

Prednisolone

Progression-free survival

B symptoms

Refractory (planetary science)

10.1080/16078454.2023.2198898

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Citations (3)

Oral Abstract: ALL-363 Comparison of Treatment Outcomes in Adolescents and Young Adults (AYA) With Philadelphia Negative Acute Lymphoblastic Leukemia (ALL) Treated With HyperCVAD and Pediatric-Inspired Protocols (PIPs)

Clinical Lymphoma Myeloma & Leukemia (2023)

Omar Shahin Mohammad Ma’koseh Kamal Al Rabie Rnad Khader Israa Shdeifat

10.1016/s2152-2650(23)00346-4

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Citations (0)