ABSTRACT Many patients with burn injuries have various complications and emotional problems due to scars. Although various modalities to improve burn scars have been attempted, such as excision of scars, skin grafts, laser abrasion and silicone product usage, the cosmetic outcomes have not been satisfactory for a large portion of patients. Herein, we describe two cases which showed satisfactory cosmetic results after treatment of burns scars with the pinhole method using a carbon dioxide (CO 2 ) laser that allowed us to make deep, closely set holes reaching down to the upper dermis. A 20‐year‐old female patient with a scar on her neck and a 25‐year‐old female patient with a scar on her right forearm after burn injuries are presented. As early as only a few weeks after the treatment, the scars showed relaxation of contracture, reduction of wrinkles and improvement of texture and color compared to before the treatment. Treatment of burn scars with the pinhole method can be easily performed and results in dramatic improvement in scar quality with only a few side‐effects.

Carbon dioxide laser

Pinhole (optics)

Abrasion (mechanical)

10.1111/j.1346-8138.2006.00198.x

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Two Cases of Acute Leukopenia Induced by Colchicine with Concurrent Immunosuppressants Use in Behçet's Disease

Yonsei Medical Journal (2008)

Kyu-Yeop Lee Do Young ‍Kim Jae Yong Chang Dongsik Bang

Colchicine-induced leukopenia usually occurrs in intentional or accidental overdoses or inappropriate use in combination with intravenous and oral colchine; however, there have been several reports of hematologic toxicity in short-term and small-dose colchicine medication courses.We present two cases of leukopenia induced by colchicine use concurrent with immunosuppressants in Behçet's disease.We postulate that the mechanism of colchicine-induced leukopenia might be the destruction of circulating leukocytes and an inhibition of leukocyte production by the immediate and direct toxic effect of colchicine on idiosyncrasies unique to each patient.The concurrently administered immunosuppressant might decrease the threshold for hematologic toxicity of colchicine in the leukocytes and their precursor cells.

Leukopenia

Colchicine

10.3349/ymj.2008.49.1.171

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Sudden eruption of pigmentary spots on vitiligo universalis patient: possible misdiagnosis

Eun Chun Han Kyu-Yeop Lee Jung-U Shin Yoon Kee Park Mi Ryung Roh

© 2009 The Authors. doi: 10.2340/00015555-581 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Vitiligo is a disease caused by loss of melanocytes. It can be classified as segmental, acrofacial, generalized and universal, or by pattern of involvement, such as focal, mixed, and mucosal types. In generalized and universal vitiligo, the entire body surface may be depigmented, leaving only a few normally pigmented macules and patches in some areas (1). Therefore it is sometimes difficult to diagnose generalized vitiligo if the patient does not show any normally pigmented macules. We report here a rare case of repigmentation after strong sun exposure in a patient diagnosed with vitiligo universalis.

Vitiligo

Pigmentation disorder

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