Mengjia Li

Bengbu Medical College

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Yunjia Shi

Zhengzhou University

Qinglin Pan

Central South University

Xiangdong Wang

Zhengzhou University

Lixiang Chen

Huazhong University of Science and Technology

Hengchao Zhang

Binzhou Medical University

Guopeng Zhang

Zhengzhou University

Bin Cai

Changchun University of Technology

Ji Ye

Second Military Medical University

Zhiqi Huang

Aluminum Corporation of China (China)

Shuhui Liu

Tianjin Polytechnic University

Cooperative Institutions

Zhengzhou University

121

Chinese Academy of Sciences

Central South University

Shanghai Jiao Tong University

First Affiliated Hospital of Zhengzhou University

Sichuan University

University of Chinese Academy of Sciences

Huazhong University of Science and Technology

Harbin Institute of Technology

Peking University

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Determination of Hot Extrusion Parameters in a Spray-Formed Ultrahigh-Strength Aluminum Alloy

Journal of Materials Engineering and Performance (2020)

Yaru Liu Xiangdong Wang Qinglin Pan Weiyi Wang Mengjia Li

Spray forming

6063 aluminium alloy

Alonizing

10.1007/s11665-020-04630-2

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Citations (4)

Effect of Sc and Zr additions on corrosion behaviour of Al–Zn–Mg–Cu alloys

Journal of Alloys and Compounds (2014)

Yunjia Shi Qinglin Pan Mengjia Li Xing Huang Bo Li

Recrystallization (geology)

10.1016/j.jallcom.2014.05.128

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Citations (145)

Quantitative capillary electrophoresis and its application in analysis of alkaloids in tea, coffee, coca cola, and theophylline tablets

Journal of Separation Science (2008)

Mengjia Li Junyi Zhou Xue Gu Yan Wang Xiaojing Huang

Abstract A quantitative CE (qCE) system with high precision has been developed, in which a 4‐port nano‐valve was isolated from the electric field and served as sample injector. The accurate amount of sample was introduced into the CE system with high reproducibility. Based on this system, consecutive injections and separations were performed without voltage interruption. Reproducibilities in terms of RSD lower than 0.8% for retention time and 1.7% for peak area were achieved. The effectiveness of the system was demonstrated by the quantitative analysis of caffeine, theobromine, and theophylline in real samples, such as tea leaf, roasted coffee, coca cola, and theophylline tablets.

Coca

Coca cola

Quantitative Analysis

10.1002/jssc.200800529

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Citations (38)

High-strain-rate superplasticity and microstructural evolution in ECAP-processed Mg–6.5Y–1.2Er–1.6Zn–0.5Ag alloy

Journal of Materials Research and Technology (2023)

Haoran Wu Jinghua Jiang Zhenquan Yang Mengjia Li Yuxuan Yuan

A warm equal-channel angular pressing (ECAP) procedure was applied to a new Mg–6.5Y–1.2Er–1.6Zn (WEZ612)–0.5Ag alloy with a long-period stacking ordered (LPSO) phase. The microstructure, superplasticity, and deformation mechanism of the WEZ612–0.5Ag alloy were then systematically investigated. Three different precipitation phases formed in the alloy with trace Ag addition, namely LPSO, γ, and nanoprecipitate phases. A remarkable elongation of 726% was attained at 623 K and a strain rate of 0.01 s−1. The strain rate sensitivity index (m) and activation energy (Q) under these deformation conditions were 0.461 and 133.08 kJ mol−1, respectively. These m and Q values confirm that the primary deformation mechanism of the WEZ612–0.5Ag alloy at 623 K was grain boundary sliding assisted by lattice diffusion. The highly stable LPSO phases, γ precipitates, and nanoprecipitates synergistically improved the superplasticity of the alloy by retarding crack propagation and grain growth and by promoting the basal plane slip.

Superplasticity

Grain Boundary Sliding

Deformation mechanism

Elongation

10.1016/j.jmrt.2023.02.092

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Citations (9)

Characterization of Human-Induced Neural Stem Cells and Derivatives following Transplantation into the Central Nervous System of a Nonhuman Primate and Rats

Stem Cells International (2022)

Mengjia Li Zhengbo Wang Tianqi Zheng Tianzhuang Huang Baoguo Liu

Neural stem cells (NSCs) and derivatives are potential cellular sources to treat neurological diseases. In the current study, we reprogrammed human peripheral blood mononuclear cells into induced NSCs (iNSCs) and inserted GFP gene into the AAVS1 site for graft tracing. Targeted integration of GFP does not affect the proliferation and differentiation capacity of iNSCs. iNSC-GFP can be further differentiated into dopaminergic precursors (DAPs) and motor neuron precursors (MNPs), respectively. iNSCs were engrafted into the motor cortex and iNSC-DAPs into the striatum and substantia nigra (SN) of a nonhuman primate, respectively. The surviving iNSCs could respond to the microenvironment of the cortex and spontaneously differentiate into mature neurons that extended neurites. iNSC-DAPs survived well and matured into DA neurons following transplantation into the striatum and SN. iNSC-MNPs could also survive and turn into motor neurons after being engrafted into the spinal cord of rats. The results suggest that iNSCs and derivatives have a potential to be used for the treatment of neurological diseases.

Neurite

10.1155/2022/1396735

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Citations (9)

Microstructure and properties of Al−2Mg−0.5Mn alloy with narrow crystallization temperature range realized by adding trace elements

Transactions of Nonferrous Metals Society of China (2023)

Mengjia Li Engui Zhang Shu-yu LIU Xiangdong Wang Yunjia Shi

The wide crystallization temperature range of Al−Mg alloys is a key factor for the surface defect formation during continuous casting and rolling process. To reduce the crystallization temperature range of the alloy, the influences of trace Zn, Si, Zr and Ti elements on the microstructure and properties of Al−2Mg−0.5Mn alloy were investigated. The X-ray photoelectron spectroscopy, atomic force microscopy, scanning and transmission electron microscopy were used for microstructural characterization. The Ti and Zr additions could refine the grain size and improve the strength of the Al−Mg−Mn alloy by forming Al3Ti and Al3Zr in the alloy, while the crystallization temperature ranges of these alloys were wider. It was revealed that Zn and Si additions could form new secondary phases with Mg in the alloy, thus reducing the actual Mg content during later eutectic solidification process. Therefore, the crystallization temperature range of Al−2Mg−0.5Mn−0.2Zn−0.2Si alloy was narrower than that of Al−2Mg−0.5Mn alloy. The mechanical properties and corrosion resistance of Al−2Mg−0.5Mn alloy were also improved by the additions of Zn and Si.

10.1016/s1003-6326(23)66306-x

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Citations (1)

Current perspectives on benzoflavone analogues with potent biological activities: A review

Arabian Journal of Chemistry (2022)

Guangxin Liu Zefeng Zhao Mengjia Li Mingrui Zhao Tongwen Xu

Medicinal chemistry investigators have isolated and synthesized benzoflavone analogues with diverse bioactivities including enzyme inhibitory activity, central nervous system (CNS) activity, anti-inflammatory activity, anti-microorganism activity, hypoglycemic activity, and receptor modulating potential. SAR (Structure-Activity Relationship) studies have been conducted extensively and plenty of benzoflavone analogues have been prepared for potential targets. Herein, we review the pharmacology properties and SAR for benzoflavone analogues, and provide a brief summarization of synthetic strategies, wishing to give perspective on the research and development of benzoflavone derivatives.

10.1016/j.arabjc.2022.104109

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Citations (1)

Field Collection and Laboratory Routine Identification of <em>Rhodiola crenulata</em>

Journal of Visualized Experiments (2023)

Jiayi Wang Na Xie Mengjia Li Jinsong Su Ya Hou

The identification of medicinal materials is the premise and guarantee of drug safety. The majority of scientific researchers are bound to favor the simple, fast, effective, and inexpensive identification process of herbals. Rhodiola crenulata is a traditional Tibetan medicine grown at high altitudes, mainly distributed in Tibet, Yunnan, and Sichuan regions of China. Rhodiola crenulate possesses multiple bioactivities, such as anti-inflammatory, anti-hypoxia, and antioxidant properties, and has great potential for development. With the increasing market demand and a rapid decrease in resource content, a large number of confused products of Rhodiola crenulata have been troubling people. Therefore, this protocol introduces a standard process for the identification of Rhodiola crenulata in the field combined with routine laboratory testing. The combination of habitat, microscopic features, and thin-layer chromatography will undoubtedly identify Rhodiola crenulata quickly, efficiently, and economically, contributing to the continuous development of Tibetan medicine and the quality control of medicinal materials.

Rhodiola

Identification

10.3791/65947

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Citations (0)

Quench Sensitivity of a 7A46 Aluminum Alloy

JOM (2019)

Ji Ye Pan Qing-lin Hang Li Zhiqi Huang Yaru Liu

Isothermal process

Isothermal transformation diagram

10.1007/s11837-019-03421-y

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