Boris I. Medarov

Albany Medical Center Hospital

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Co-Authors

Marc A. Judson

Albany Medical Center Hospital

Leonard J. Rossoff

Albert Einstein College of Medicine

Biplab K. Saha

Albany Medical Center Hospital

Aaron B. Waxman

Brigham and Women's Hospital

Ali Wazir

SUNY Upstate Medical University

Woon H. Chong

Ng Teng Fong General Hospital

Tejo Challa

Baptist Health Foundation

Shraddha Tongia

Piedmont Athens Regional

Steven D. Nathan

Inova Fairfax Hospital

Johnathan Sun

Albany Medical Center Hospital

Cooperative Institutions

Albany Medical Center Hospital

Pulmonary and Critical Care Associates

United Therapeutics (United States)

National Heart Lung and Blood Institute

Long Island Jewish Medical Center

Albert Einstein College of Medicine

Pulmonary and Allergy Associates

Icahn School of Medicine at Mount Sinai

Triangle

Harvard University

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West Nile meningoencephalitis and rhabdomyolysis

The Lancet Infectious Diseases (2004)

Boris I. Medarov Alan S Multz Wendy Brown Larissa Lempert

West Nile virus

10.1016/s1473-3099(04)01229-0

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Citations (15)

A Novel Approach to Clinical Change Endpoints: A Win Ratio Analysis of the INCREASE Trial

Annals of the American Thoracic Society (2023)

Steven D. Nathan Boris I. Medarov Lawrence Ho John Kingrey T. Hong

"A Novel Approach to Clinical Change Endpoints: A Win Ratio Analysis of the INCREASE Trial." Annals of the American Thoracic Society, 0(ja), pp.

Annals

Surrogate endpoint

Clinical endpoint

10.1513/annalsats.202303-229rl

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Citations (2)

Assessing the reliability of obstructive sleep apnea screening instruments in isolation or in combination

Respiratory Medicine X (2020)

Boris I. Medarov Luke A. Pluto Lauren Fina Furqan Ilyas Indrawattie Sukhu

A) Compare the standard obstructive sleep apnea (OSA) screening instruments to each other and to the judgement of experienced sleep clinicians. B) Evaluate if a novel OSA screening instrument constructed from components of the standard OSA screening instruments would improve the accuracy of screening. We screened 344 subjects using the most commonly used OSA screening instruments- Berlin sleep questionnaire, STOP, STOP-BANG, Mallampati upper airway score and Epworth sleepiness scale. A clinical impression score (CIS) reflected the clinician's likelihood of OSA being present. All subjects underwent nocturnal polysomnography. The sensitivity and specificity of all screening instruments and the CIS for any OSA and for moderate-to-severe OSA were calculated. We constructed a logistic regression model incorporating all the components of these OSA screening instruments in an effort to develop a more accurate OSA screening metric. STOP-BANG was the most sensitive instrument (sensitivity of 93% and 97% for any OSA and moderate-to-severe OSA respectively). Its ability to exclude OSA was on par with the CIS (sensitivity of 95% and 97% respectively). The logistic regression model incorporating all the individual items of the OSA screening instruments did not meaningfully improve accuracy. A comprehensive clinical evaluation and STOP-BANG both possess sufficiently high sensitivity to be useful screening tools. Combining the existing OSA screening instruments into a single instrument did not appreciably improve upon the accuracy of the STOP-BANG. Further refinements of the existing OSA screening instruments would require identifying new, easily recognizable risk factors.

Epworth Sleepiness Scale

10.1016/j.yrmex.2020.100019

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Citations (1)

Legionella micdadeiInfection Presenting as Severe Secretory Diarrhea and a Solitary Pulmonary Mass

Clinical Infectious Diseases (2004)

Boris I. Medarov Anita K. Siddiqui Tahir Mughal Mark Moshiyakhov Leonard J. Rossoff

Sixty percent of infections with non-pneumophila species of Legionella are caused by Legionella micdadei. Although diarrhea is a common symptom of legionellosis, including that due to L. micdadei infection, severe, life-threatening diarrhea is rare. We describe a patient with profound secretory diarrhea (secretion rate, up to 8 L/day) that was secondary to culture-proven L. micdadei pneumonia. In addition, a 3-cm pulmonary nodule was detected, which completely resolved after proper treatment for Legionella infection. Resolving pulmonary nodules have been previously reported in association with treatment of L. micdadei infections.

Legionella

10.1086/382679

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Citations (11)

NIVOLUMAB-INDUCED MYOCARDITIS, MYOSITIS, AND RESPIRATORY FAILURE

CHEST Journal (2019)

Wafic Itani Ali Wazir Amit Chopra Boris I. Medarov

Pneumonitis

10.1016/j.chest.2019.08.2058

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Citations (0)

Sinoatrial block complicating legionnaire’s disease

Postgraduate Medical Journal (2003)

Boris I. Medarov Shraddha Tongia Leonard J. Rossoff

Abstract A 59 year old woman presented with acute onset of fever, chills, diaphoresis, vague chest discomfort, and was found to be hypotensive and tachypnoeic. An electrocardiogram demonstrated sinoatrial block with a junctional rhythm between 50 and 80 beats/min. All cultures were negative and imaging studies unrevealing. Her urine tested positive for Legionella pneumophila antigen serotype 1 and she improved with antibiotic therapy.

Chills

Junctional rhythm

Legionnaires' disease

10.1136/pmj.79.937.657

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Citations (1)

Hour-to-hour variation of FEV1/FVC

CHEST Journal (2004)

Boris I. Medarov

Variation (astronomy)

10.1378/chest.126.4_meetingabstracts.744s-b

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