Yuping Tang

Shaanxi University of Chinese Medicine

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Jin‐Ao Duan

Nanjing University of Chinese Medicine

226

Shi‐Jun Yue

Shaanxi University of Chinese Medicine

Erxin Shang

Nanjing University of Chinese Medicine

Jianming Guo

Nanjing University of Chinese Medicine

Zhang Li

Bethune International Peace Hospital

Dawei Qian

Nanjing University of Chinese Medicine

Shulan Su

Nanjing University of Chinese Medicine

Guisheng Zhou

Nanjing University of Chinese Medicine

Ding‐Qiao Xu

Shaanxi University of Chinese Medicine

Yan‐Yan Chen

Fudan University

Cooperative Institutions

Nanjing University of Chinese Medicine

292

Shaanxi University of Chinese Medicine

196

Chinese Academy of Sciences

155

China Pharmaceutical University

Nanjing University

University of Chinese Academy of Sciences

Chinese Academy of Medical Sciences & Peking Union Medical College

Fudan University

Shanghai Jiao Tong University

Peking University

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Ultra-performance liquid chromatography–tandem mass spectrometry analysis of the bioactive components and their metabolites of Shaofu Zhuyu decoction active extract in rat plasma

Journal of Chromatography B (2009)

Shulan Su Jianming Guo Jin‐Ao Duan Tuanjie Wang Dawei Qian

Isorhamnetin

Decoction

Flavones

Glucuronide

10.1016/j.jchromb.2009.11.048

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Citations (42)

Natural redox mediator anthraquinone aloe-emodin facilitated the in-situ mineralized γ-FeO(OH) membrane for the removal of tannic acid through photocatalytic-PMS activation

Journal of Hazardous Materials (2024)

Jiajia Li Mengzhen Zhu Manhua Chen Qiong Mei Wenzhuo Chen

Tannic acid

Anthraquinones

Mediator

Aloe emodin

Anthraquinones

10.1016/j.jhazmat.2024.135464

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Citations (2)

A Novel Fluorescent Probe for Formaldehyde Based on Hydrazone Formation for Real Food Samples Detection and Bioimaging

Weifang Luo Qian Wang Mengpei Xie Wenzhuo Chen Mengyi Shen

Formaldehyde (FA) is an active carbonyl structure, that is widely used in people's daily life, such as: preservatives, fixatives, etc. Furthermore, formaldehyde is highly toxic and has been listed as one of the three major indoor pollutants. Therefore, the development of some highly sensitive and selective fluorescent probes is of great biological importance. In this article, probe X is designed to identify formaldehyde by a light-induced electron transfer (PET) process between the naphthalimide derivative and the hydrazine group based on hydrazone formation. Moreover, the probe has good optical response and excellent linearity over a wide FA concentrations range, ensuring FA concentration values in real complex food samples can be quantitatively recorded. In addition, the probe can monitor the changes in formaldehyde level in living cells with good biocompatibility and image resolution.

Hydrazone

10.2139/ssrn.4807575

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A novel fluorescent probe for formaldehyde based on hydrazone formation for real food samples detection and bioimaging

Journal of Molecular Structure (2024)

Qian Wang Mengpei Xie Wenzhuo Chen Mengyi Shen Qian Zhang

Hydrazone

10.1016/j.molstruc.2024.140184

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The association between serum folate and gestational diabetes mellitus: a large retrospective cohort study in Chinese population

Public Health Nutrition (2022)

Xiao-Hui Liu Zhijuan Cao Li-Wei Chen Dong-Lan Zhang Xiaoxian Qu

To investigate the association between folate levels and the risk of gestational diabetes mellitus (GDM) risk during the whole pregnancy.In this retrospective cohort study of pregnant women, serum folate levels were measured before 24 gestational weeks (GW). GDM was diagnosed between 24th and 28th GW based on the criteria of the International Association of Diabetes and Pregnancy Study Groups. General linear models were performed to examine the association of serum folate with plasma glucose (i.e. linear regressions) and risk of GDM (i.e. log-binomial regressions) after controlling for confounders. Restricted cubic spline regression was conducted to test the dosage-response relationship between serum folate and the risk of GDM.A sigle, urban hospital in Shanghai, China.A total of 42 478 women who received antenatal care from April 2013 to March 2017 were included.Consistent positive associations were observed between serum folate and plasma glucose levels (fasting, 1-h, 2-h). The adjusted relative risks (RR) and 95 % CI of GDM across serum folate quartiles were 1·00 (reference), 1·15 (95 % CI (1·04, 1·26)), 1·40 (95 % CI (1·27, 1·54)) and 1·54 (95 % CI (1·40, 1·69)), respectively (P-for-trend < 0·001). The positive association between serum folate and GDM remained when stratified by vitamin B12 (adequate v. deficient groups) and the GW of serum folate measurement (≤13 GW v. >13 GWs).The findings of this study may provide important evidence for the public health and clinical guidelines of pregnancy folate supplementation in terms of GDM prevention.

Quartile

10.1017/s136898002200194x

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Citations (4)

Editorial: New insights into renal fibrosis and therapeutic effects of natural products volume II

Frontiers in Pharmacology (2022)

Dan‐Qian Chen Yan Guo Zhiyong Guo Yuping Tang

EDITORIAL article Front. Pharmacol., 28 October 2022Sec. Renal Pharmacology Volume 13 - 2022 | https://doi.org/10.3389/fphar.2022.1053408

10.3389/fphar.2022.1053408

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Citations (2)

An efficient partial synthesis of 4′-O-methylquercetin via regioselective protection and alkylation of quercetin

Beilstein Journal of Organic Chemistry (2009)

Nian‐Guang Li Zhi‐Hao Shi Yuping Tang Jianping Yang Jin‐Ao Duan

An efficient partial 5-step synthesis of 4′- O -methylquercetin from quercetin in 63% yield is reported. This strategy relies on the selective protection of the catechol group with dichlorodiphenylmethane in diphenyl ether as solvent and on the selective protection of the hydroxyl groups at positions 3 and 7 with chloromethyl ether.

Catechol

Protecting group

10.3762/bjoc.5.60

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Citations (21)

Characterization of Triterpenic Acids in Fruits of Ziziphus Species by HPLC-ELSD-MS

Journal of Agricultural and Food Chemistry (2010)

Sheng Guo Jin‐Ao Duan Yuping Tang Nian‐Yun Yang Dawei Qian

The fruits of Ziziphus species have been utilized as food as well as crude drugs for their health benefits in China for thousands of years. This paper reported a reversed-phase high-performance liquid chromatography (HPLC) method for the simultaneous characterization and quantitation of 11 triterpenic acids in chloroform extracts of jujube fruits by using an evaporative light scattering detector (ELSD) and electrospray ionization-mass spectrometry (ESI-MS). The results showed that the contents of triterpenic acids in the fruits of Ziziphus jujuba var. spinosa were higher than those in the fruits of Z. jujuba, especially for the compound pomonic acid. Differences were also found among the different parts of Z. jujuba var. spinosa fruits with the sarcocarp having a higher amount of triterpenic acids than the seed and hard core.

Chromatography detector

10.1021/jf101022p

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Citations (113)

Determination of extracellular 5-HIAA in the brains of normal and primary dysmenorrheal rats by microdialysis coupled with HPLC-ECD and its application in evaluation of Xiang-Fu-Si-Wu Decoction efficacy

Zhonghua zhongyiyao zazhi (2011)

Yuping Tang

Objective:To observe the effects of Xiang-Fu-Si-Wu Decoction(香附四物汤,XFSWD) on extracellular 5-HIAA in the brains of normal and primary dysmenorrheal rats and to explore the possible mechanism of XFSWD in treating primary dysmenorrheal.Methods:Estradiol benzoate and oxytocin were used to make primary dysmenorrheal rats model.5-HIAA in hypothalamus of normal and primary dysmenorrheal model rats were rapidly identified using microdialysis coupled with HPLC-ECD.Results:The limits of detection(LOD) and quantification(LOQ) for 5-HIAA in microdialysis sample were 1.5 ng/mL and 5.0 ng/mL respectively.The calibration curve was linear over a concentration range of 10-250 ng/mL.The contents of 5-HIAA increased notably in dysmenorrheal model rats compared to normal control group,which suggested primary dysmenorrhea lead to the increase of 5-HIAA.After treatment with XFSWD,the contents of 5-HIAA decreased.Conclusion:XFSWD relieve pain syndrome of primary dysmenorrhea through decreasing the metabolism rate of 5-HT in hypothalamus.

Microdialysis

Decoction

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Citations (4)

[Dose-effect relationship of traditional Chinese medicine formula for promoting blood circulation to remove stasis on ADP-induced platelet aggregation and rabbit plasma thrombin time].

China Journal of Chinese Materia Medica (2009)

Yanhua Zhang Yuping Tang Jianming Guo Anwei Ding Jin‐Ao Duan

To investigate the effect of five traditional Chinese medicine formula for promoting blood circulation to remove stasis (Xuefuzhuyu Tang, Shaofuzhuyu Tang, Gexiazhuyu Tang, ShentongZhuyu Tang, Tongqiaohuoxue Tang) on platelet aggregation and clotting time in a dose-response relationship.The platelet aggregation was tested with Born's method and thrombin time (TT) method was established to determine the clotting time.The formula for promoting blood circulation to remove stasis showed significant inhibitory effects on the platelet aggregation and prolonged clotting time, the supernate of 80% alcohol solution showed the most potent inhibitory activity among the three kinds of samples from one formula (P < 0.01), especially the supernate of Shaofuzhuyu Tang and Gexiazhuyu Tang were better than other formula on platelet aggregation. About the anticoagulant, the whole formula showed the evidently prolonging the clotting time than other two fractions (P < 0.01) and the precipitation were the worst.The formula for promoting blood circulation to remove stasis showed significant effect on platelet aggregation and clotting time, and different samples of the formula had different efficacy. The study established a foundation for further bio-activity evaluation of these formulae and provided evidence for the treatment of cardiovascular and cerebrovascular diseases.

Blood stasis

Clotting time

Blood circulation

Blood clotting

Thrombin time

Clot formation

Bleeding time

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Citations (3)