Jesús Hernán González-Cortés

Universidad Autónoma de Nuevo León

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Jesús Mohamed-Hamsho

Ophthalmology Associates (United States)

Jesus Emiliano Gonzalez-Cantu

Universidad Autónoma de Nuevo León

Alper Bilgic

Berner Augenklinik am Lindenhofspital

Aditya Sudhalkar

Retina Research Foundation

Sergio E. Hernández-Da Mota

Universidad de Morelia

Alan Baltazar Treviño-Herrera

Universidad Autónoma de Nuevo León

Laurent Kodjikian

Hôpital de la Croix-Rousse

Thibaud Mathis

Matériaux Ingénierie et Science

Francesc March de Ribot

University of Otago

Abraham Olvera‐Barrios

Moorfields Eye Hospital NHS Foundation Trust

Cooperative Institutions

Universidad Autónoma de Nuevo León

Hospital Universitario Dr José Eleuterio Gonzalez

Asociacion Para Evitar la Ceguera en México Hospital Dr. Luis Sánchez Bulnes

Tecnológico de Monterrey

Universidad Nacional Autónoma de México

Weatherford College

University Medical Center Hamburg-Eppendorf

Universität Hamburg

Mexican Social Security Institute

Universidad Nuestra Señora de La Paz

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Primer consenso nacional de edema macular diabético

Revista Mexicana de Oftalmología (2021)

Gerardo García‐Aguirre Renata García-Franco Jans Fromow-Guerra Ximena Mira-Lorenzo Abel Ramírez-Estudillo

Diabetic macular edema

10.24875/rmo.m21000206

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Topical Triamcinolone Acetonide-Loaded Liposomes Formulation Used as an Adjuvant to Intravitreal Ranibizumab Therapy for Neovascular Age Related Macular Degeneration

José Navarro‐Partida Juan Carlos Altamirano-Vallejo Luis Abraham Aceves Franco Jesús Hernán González-Cortés Sergio Hernandez Da Mota

Novel strategies have been developed to reduce or to avoid the intravitreal injections (IVTs) of the antiangiogenic (ranibizumab; RBZ) and the anti-inflammatory (triamcinolone acetonide; TA) agents used to treat vitreoretinal diseases. One of the strategies include liposomes. In this study, it was evaluated the safety and efficacy of topical triamcinolone-loaded liposomes formulation (TALF) as an adjuvant to intravitreal RBZ therapy in treatment-naive patients with neovascular age related macular degeneration (nAMD). Subjects were randomly assigned to the RBZ-TALF or the RBZ-pro re nata (RBZ-PRN) group. Patients from the RBZ-TALF group were instructed to apply TALF for a 12-month period after a single dose of RBZ. Patients from the RBZ-PRN group received three monthly RBZ-IVTs. Retreatment with RBZ was considered in case of nAMD reactivation. Related to safety, non-ocular abnormalities were observed during TALF therapy. Owing to the efficacy, non-significant differences are identified in visual acuity or central foveal thickness when the RBZ-PRN and RBZ-TALF groups are compared. Importantly the average number of RBZ injections was significantly lower in the RBZ-TALF group (2.5 ± 1.4 vs 6.1 ± 1.3 IVTs; p=0004). Therefore, TALF used as an adjuvant to RBZ reduce the number of RBZ-IVTs retreatment with optimal visual and anatomic results.

10.20944/preprints202106.0585.v1

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Anatomical Changes of Full-Thickness Macular Hole Documented by Microscope-Integrated Spectral-Domain Optical Coherence Tomography

Ophthalmic surgery, lasers & imaging retina (2018)

Jesús Hernán González-Cortés A. Ramírez Estudillo Jorge Arturo Sánchez-Ramos Yunuen Bages-Rousselon Mariana Fernandez-Mar

BACKGROUND AND OBJECTIVE: To evaluate anatomical changes of idiopathic macular hole (MH) after internal limiting membrane removal and after passive suction at the hole's borders using microscope-integrated intraoperative optical coherence tomography (iOCT). PATIENTS AND METHODS: Five eyes of five subjects with full-thickness idiopathic MH underwent phacoemulsification, intraocular lens implantation, pars plana vitrectomy, and internal limiting membrane (ILM) removal. iOCT was performed after ILM removal and after passive suction at the hole's borders. RESULTS: iOCT showed decreased MH diameter after ILM removal in all cases. Passive suction achieved complete apposition of borders. All cases presented successful postsurgical closure. CONCLUSIONS: iOCT provides anatomical information during MH surgery that may impact surgical decision-making by allowing a real-time evaluation of structures. iOCT with preservative-free triamcinolone acetonide enhanced ILM visualization. Its use is superior to iOCT alone for the identification of vitreomacular interface structures. [ Ophthalmic Surg Lasers Imaging Retina . 2018;49:e105–e111.]

Internal limiting membrane

10.3928/23258160-20180907-17

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Closure of stage 2 macular hole with a low-dose intravitreal injection of perfluoropropane.

Cirugía y Cirujanos (2019)

Jesús Hernán González-Cortés Abraham Olvera‐Barrios Hugo Alejandro Treviño-Rodríguez Jesus Emiliano Gonzalez-Cantu Jesús Mohamed-Hamsho

Idiopathic macular holes (IMH) are common and affect central vision. We demonstrate the effectiveness of 0.2 ml intravitreal perfluoropropane (C3F8) in Stage-2 IMH.A 61-year-old woman presented with blurred vision OD. Best-corrected visual acuity (BCVA) was 20/125 OD and 20/20 OS. Biomicroscopy of OD evidenced a Stage-2 IMH. Intravitreal C3F8 was injected and postural measures prescribed. Optical coherence tomography 1 week after revealed posterior vitreous detachment and vitreomacular traction resolution. Full anatomical and functional recovery was achieved at week 4 and remained stable during a 6-month follow-up (BCVA 20/20 OD).Intravitreal C3F8 as initial therapy for Stage 2 IMH represents a good alternative to vitrectomy for patients with IMH.Los agujeros maculares idiopáticos (AMI) son comunes y afectan la visión central. Demostramos la efectividad de 0.2 ml de perfluoropropano (C3F8) intravítreo en AMI en estadio 2.Una mujer de 61 años presentó con visión borrosa súbita OD. Mejor agudeza visual corregida (MAVC) 20/125 OD y 20/20 en el OS. La biomicroscopía del OD evidenció un AMI en estadio 2. Se inyectó C3F8 intravítreo y se prescribieron medidas posturales. Una semana después, la tomografía de coherencia óptica reveló desprendimiento de vítreo posterior. La resolución de tracción vitreomacular con recuperación anatómica y funcional completa se logró a la semana 4 y se mantuvo estable durante un seguimiento de 6 meses (MAVC 20/20 OD).El C3F8 intravítreo como terapia inicial para AMI en estadio 2 representa una buena alternativa a la vitrectomía vía pars plana en pacientes con AMI.

10.24875/ciru.18000363

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Long-term visual and anatomic outcomes after photodynamic therapy for symptomatic circumscribed choroidal hemangioma

Cirugía y Cirujanos (2019)

Jesús Hernán González-Cortés Abraham Olvera‐Barrios Jose R. Perez-Salas Hugo Alejandro Treviño-Rodríguez Ezequiel E. Treviño-Cavazos

long-term visual and anatomic outcomes after photodynamic therapy for symptomatic

10.24875/ciru.18000362

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Citations (1)

Treatment Algorithm in Proliferative Diabetic Retinopathy - From Protocols to the Real World

IntechOpen eBooks (2021)

Jesús Hernán González-Cortés Jesus Emiliano Gonzalez-Cantu Aditya Sudhalkar Sergio E. Hernández-Da Mota Alper Bilgic

Diabetes mellitus is a global epidemic that leads to multiple macrovascular and microvascular complications. The complex interrelated pathophysiological mechanisms triggered by hyperglycemia underlie the development of diabetic retinopathy (DR). Proliferative diabetic retinopathy (PDR) is a microvascular complication, considered the main cause of irreversible blindness in patients of productive age in the world. On the other hand, diabetic macular edema (DME) remains the clinical feature most closely associated with vision loss. In general, both manifestations are due to an increase in inflammatory factors, such as specific pro-inflammatory prostaglandins, interleukins and angiogenic substances including vascular endothelial growth factor (VEGF). Laser photocoagulation and VEGF inhibitors have been shown to be effective in the treatment of PDR and DME. Currently, randomized protocols suggest that VEGF inhibitors therapy could displace laser photocoagulation in the treatment of PDR with and without the presence of DME. The ongoing discussion still prevails about the different treatment modalities for both retinal manifestations in real-world settings.

Pathophysiology

10.5772/intechopen.99843

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Citations (1)

Presión intraocular en pacientes con aceite de silicona

Revista Mexicana de Oftalmología (2004)

Jesús Hernán González-Cortés Alejandro Martínez López-Portillo Ezequiel Enrique Treviño-Cavazos Francisco Javier Bermejo-de la Peña Jesús Mohamed-Hamscho

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SPONTANEOUS CLOSURE OF SIMULTANEOUS IDIOPATHIC MACULAR HOLES DOCUMENTED BY SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY

Retinal Cases & Brief Reports (2018)

Jesús Hernán González-Cortés Juan J. Toledo-Negrete Yunuen Bages-Rousselon Manuel A. de Alba-Castilla Jesús Mohamed-Hamsho

To report a case of spontaneous closure of simultaneous full-thickness macular hole.Case report and literature review.A 67-year-old woman with small-diameter simultaneous macular holes was observed for a period of 5 months, and progression was documented with spectral-domain optical coherence tomography. Closure of right full-thickness macular hole was evidenced by 1 month and left full-thickness macular hole by 5 months.This case demonstrates possible spontaneous resolution of a condition that is usually treated surgically. A period of observation with serial imaging studies may be advised in cases of small macular holes.

10.1097/icb.0000000000000749

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Citations (11)

Diabetic Renal-Retinal Syndrome and Inflammatory Markers of Acute Phase

Journal of Diabetes Mellitus (2014)

Francisco Sepúlveda-Cañamar Raúl Treviño Hernández Joaquín Darío Treviño Baéz Jesús Hernán González-Cortés

Objective: To determine the association between the acute inflammatory markers and Diabetic Renal-Retinal Syndrome in our patients. Methods: A total of 44 patients were included in this transverse (cross sectional), observational, analytical, and comparative study. Two groups of patients were created. Results: In patients with chronic renal failure, stages 3, 4, or 5 (scale 1 to 5) were identified and divided into two groups: Group I (Patients with concomitant diabetic retinopathy stabilized with photocoagulation) 22 patients. Group II (Patients with progression of retinopathy, after photocoagulation, in the form of intraocular bleeding) 22 patients. The number of patients with chronic renal failure in stage 3 was: Group I; 16. In Group II; 12 patients (OR: 1.0). Stage 4: Group I; 4 patients. Group II: 3 patients (OR: 1.0, CI 95%; 0.3843 - 2.021). Stage 5: Group I; 2 patients. Group II; 7 patients (OR: 1.8148, CI 95%; 1.0448 - 3.1523; Chi-squared (x2) 2.7450, p = 0.097). t-Test found statistical significance in Erythrocyte Sedimentation Rate (ESR): p

Erythrocyte sedimentation rate

Concomitant

10.4236/jdm.2014.43028

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Postoperative Aspergillus Infection: A Case Series

Ocular Immunology and Inflammation (2022)

Alper Bilgic Laurent Kodjikian Jesús Hernán González-Cortés Alexandra Heuvels Per Heuvels

To report the clinical findings, therapy and outcomes of pauci-symptomatic Aspergillus infection in 11 eyes of 11 patients who had recently undergone uneventful cataract surgery and IOL implantation in a single operating room on the same day.Retrospective, observational study that looks at 11 patients who demonstrated Aspergillus infection after cataract surgery. All data were collected and intracameral samples sent for microscopic evaluation and culture. Additional swabs were sent from the operating room and operative consumables.A total of 11 eyes of 11 patients were included in the analysis and were followed for at least 12 months. All patients responded completely to local and systemic voriconazole therapy. The source of infection was noted to be air-conditioning vents. Eyes with manual small incision cataract surgery (11/17) had a higher propensity for infection.Pauci-symptomatic aspergillosis infection has been reported here following cataract surgery.

10.1080/09273948.2022.2103714

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