Cervical cancer is the most common malignancy of the female genital tract in Korea. The most common histologic type of cervical cancer is squamous cell carcinoma. The simultaneous occurrence of histologically distinct squamous cell carcinoma of the cervix and invasive adenocarcinoma of the cervix is extremely unusual. We have experienced two cases of synchronous squamous cell carcinoma and adenocarcinoma of the uterine cervix. We report these cases with a brief review of the literature.
Secondary breast hemangiosarcomas are a very raremalignancy and usually divided into two subtypes: lym-phedema-associated cutaneous hemangiosarcomas andpostirradiation hemangiosarcomas (PIHs) (1, 2). PIHsare usually found in older women, who performedbreast-conserving therapy and radiation therapy, sever-al years after radiation therapy (1). According to previ-ous reports, PIHs show a low incidence of 0.05-1.11%(2). However, the increasing use of breast-conservingtherapy will predictably lead to an increased number ofPIHs (3). In addition, the rate of local recurrence of PIHsis as high as 73%, and the five-year-survival rate is only10-35% (4). Therefore, a high index of suspicion and anunderstanding of the imaging characteristics about thisdisease entity are necessary when dealing with patientswith PIHs. Here we present mammographic and sono-graphic findings of a case of locally recurred secondaryhemangiosarcoma in the context of prior breast-conser-vation therapy and radiation. Case ReportIn January 2001, a 50-year-old woman underwentbreast-conserving surgery with sentinel node biopsy ofthe ipsilateral axilla for a breast cancer in her rightbreast at our institution. The histologic report showed a1.6 cm, well-differentiated infiltrating ductal carcinoma.The resection margins were free of tumor, but onelymph node had micrometastasis of less than 2 mm. Thefinal TNM classification was T1N0M0. The patient un-derwent adjuvant external radiation therapy in the rightbreast with of 50.4 Gy plus a 9 Gy, as a boosting dose,for a total of 59.40 Gy over 50 days and five cycles of ad-juvant chemotherapy with a cyclophosphamide anddoxorubicin regimen. An annual follow-up mammogra-phy and biannual sonography revealed postoperative orradiation therapy-induced changes with no suspicious
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