Objective Comparing the two ways intravenous ling BD-needle aspiation catheter tube infusion of Aiyishu (Disodium Cantharidinate and Vitamin B6 Injection) affect blood vessels.protect the blood vessels in patients.alleviate the pain caused by phlebitis. Method The 76 cases of female breast cancer patients were randomly divided into two groups.Jugular veins cathether needle retention BD group has 33 cases.Forearm veins catheter needle retention BD group has 43 cases.Comparing the two groups observed in patients with Aiyishu infusions of speed, the incidence of phlebitis, the BD' s indwelling catheter time and so on. Result There were differences between the two groups in Aiyishu infusions of speed (P0.05). There were signifi cent differences in the incidence of phlebitis and the BD' s indwelling catheter time between the Jugular vein group and the Forearm veins groups(P0.01). Conclusion The Jugular vein group was superior to forearm veins groups, regarding the request long time infusion Aiyishu’s patients, we suggest the fi rst choice is the Jugular vein catheter.