The mental health of the person must be healthy for being responsible for the crime committed. In this study, socio-demographic and clinical characteristics as well as assessments about criminal responsibilities of the patients who were under forensic observation for crimes committed in the military environment was evaluated. Medical records of the 1,482 patients who were referred with the aim of forensic observation within a period of five years were studied retrospectively. The average age of the patients was 26.6 ± 8.2 years and education levels were 8.6 ± 2.2 years. Fifty-seven percent had a history of substance abuse, drug addiction rate was 1.2%. 22.3% of the cases were evaluated within the 32nd article of Turkish Penal Code (TPC). Diagnoses of patients assessed under 32nd article of TPC was psychotic disorder (61.9%), mental retardation (13.3%) and bipolar disorder (13%), respectively. 19.23% of the cases had previous criminal histories. Level of education of patients with a previous criminal history was lower (7.73 ± 1.36 years). There was also significant difference between groups with and without previous criminal history in terms of diagnosis of antisocial personality disorder and substance abuse history (p
Objective: Schizophrenia involves white matter abnormalities that might have a central role in the pathophysiology. Abnormal brain connectivity especially in prefrontal and temporal heteromodal cortex has been suggested as the leading structural impairment in patients with schizophrenia. In this study we examined the relationship between potential white matter changes and clinical response, as well as associations with antipsychotic treatment follow-up.Methods: 18 first-episode schizophrenia (FES) patients were recruited from the outpatient unit of the GATA (Gulhane Military Medical Academy) Haydarpasa Research and Training Hospital, between June 2009-February 2010. Fourteen patients with FES were recruited, and 16 healthy control subjects were recruited from the community. Diffusion tensor MRI (DT-MRI) was obtained from participants at baseline and after 4 weeks of standard antipsychotic treatment. A color-coded fractional anisotropy map for each 11 patient was extracted from the 4-week follow-up and the baseline splenium and genu FA measurements. According to Basser and others major eigenvector linear maps were transformed into the color-coded maps. Differences in Positive and Negative Syndrome Scale (PANSS) scores and Brief Psychiatric Rating Scale (BPRS) scores between baseline and follow up were also evaluated.Results: In this study; in the FES patients, both genu FA (p=0.001) and the splenium FA (p=0.013) values were statistically significantly lower than the healthy control group. There were mild FA increases respectively genu and splenium (p=0.533, p=0.318) in the FES patients after the treatment. But the FA changes did not correlate with the changes in clinical symptoms. A negative, moderate, statistically significant correlation (Pearson's r=-0.569, p=0.034) was found between baseline splenium FA values and BPRS scores. The duration of illness prior to treatment was negatively, weak, statistically non-significantly correlated (r=-0.066; p=0.846) between baseline and follow-up splenium FA changes.Conclusions: The reduced mean Callosal FA (CFA) values might indicate myelination defects and problems in axonal transport. The existence of white matter changes even in first episode drug-naive schizophrenia patients supports the view that these problems occurs in earlier stages of development. Although the callosal FA changes did not correlate with symptom improvement or the dose of antipsychotic medication, there was a mild increase in follow-up FA measurements. These findings show that CC which is the main conduit of interhemispheric connection is affected distinctly in patients with schizophrenia. Further collaborative studies are needed to clarify the potential long-term effects of antipsychotics on white matter microstructure and also its reversibility.
Amaç: Bu çalışmanın amacı antisosyal kişilik bozukluğu (AKB) olan hastalar ile sağlıklı bireyleri cinsel yolla bulaşan hastalık (CYBH) ve kan yoluyla bulaşan hastalık (KYBH
Myasthenia gravis (MG), is a chronic, autoimmune disease involving neuromuscular junctions [1]. Psychopathological disturbances and misdiagnosed as a psychiatric disorder are frequently reported in patients with MG because of variable and fluctuating course of disease [2]. However, during the course of the disease, mainly depression and anxiety disorders can be added to the clinics [1]. Case The complaints such as weakness, difficulty swallowing and speaking that worsening at evening, may be easily supposed neurotic disorders, in a twenty-two year old male patient, has started about two months ago. In neurology clinic, in requested psychiatric consultation; there were complaints like inability to breathe, sweating, palpitations, reluctance, pessimism and unhappiness. The patient has diagnosed according to DSM IV-TR as “Agoraphobia without panic disorder” and “Major Depression, Single Episod”. Escitolopram titrated by 20 mg/day has started. Depressive and agoraphobic symptoms have disappeared at the end of four weeks (HAM-A-D:24;11-21;9). Discussion MG patients, especially during the beginning of disease symptoms in almost all patients with the appeal was referred to the psychiatric services and 1/3 of it has been reported as psychiatric mis-diagnosis [1,2]. Choice of psychotropic drugs is important that do not affect the respiratory center and neuromuscular transmission. Agents, used in the treatment of MG, can inflame psychopathology and can create resistance to psychotropic treatment. Therefore, cooperation of neurologist and psychiatrist is important.
Delusional parasitosis (DP) is a very rare chronic psychiatric disorder.Although there are no any clinical symptoms in patients, there is a false and fixed belief that they are infected with parasites.Folie á famille is characterized as a shared psychotic disorder within all the family members.Herein, we present a family total of five people including mother, father, daughter, grandmother and grandfather who diagnosed with DP and have shared psychotic disorder.
Aggression is associated with the hyper arousal symptoms in Post-Traumatic Stress Disorder (PTSD). Biological and psychological factors play a role in the etiology of aggressive behavior. In this study, we aimed to investigate the relationship between dissociation and aggressive behavior in patients with PTSD. 42 patients with a diagnosis of PTSD according to DSM-IV criteria and 41 healthy subjects were enrolled to the study. Socio-demographic data form, the Clinician-Administered PTSD Scale (CAPS), Dissociative Experiences Scale (DES) and the Buss Perry Aggression Scale tests were administered to the participitants. DES scores, CAPS hyper arousal scores and number of experienced trauma were higher in the PTSD patients with high levels of aggression than the PTSD patients with low levels of aggression. The results suggested that dissociative symptoms should be screened carefully in PTSD patients who had aggressive behaviours prominently.
Several studies have shown that stress due to workplace is common among nurses. In this study, we aimed to assess coping attitudes of nurses working in a university hospital according to their anxiety levels and to reveal the relationship between them. Eighty nurses working at Gulhane Military Faculty of Medicine Training Hospital and who has no psychiatric complaints were enrolled. All participants completed sociodemographic data form and self-reported Beck Anxiety Inventory (BAI) and Coping Attitudes Scale (COPE). Then the study group was divided into two groups according to their BAI scores. The relationship between anxiety levels and COPE subscale scores of the two groups was assessed. In the statistical analyses, for the comparisons of continuous variables between the two groups the Mann-Whitney U test was used. Significance level was set at p < 0.05. It was found that in the group of high level anxiety, active coping subscale scores of problem-focused coping were lower than the group with lower levels of anxiety. Denial and focus on and venting of emotions subscale scores of dysfunctional coping subscale were also found to be higher in the group of high level anxiety. According to the findings of this study, dysfunctional coping attitudes may be associated with anxiety symptoms. We concluded that determination of work-related stresses of nurses and coping with these stress situations by regulating the work conditions with specific intervals might be beneficial in terms of productivity. Further researches with larger sample size would provide more meaningful information on this subject.
Myasthenia gravis (MG), is a chronic, autoimmune disease involving neuromuscular junctions [1]. Psychopathological disturbances and misdiagnosed as a psychiatric disorder are frequently reported in patients with MG because of variable and fluctuating course of disease [2]. However, during the course of the disease, mainly depression and anxiety disorders can be added to the clinics [1]. Case The complaints such as weakness, difficulty swallowing and speaking that worsening at evening, may be easily supposed neurotic disorders, in a twenty-two year old male patient, has started about two months ago. In neurology clinic, in requested psychiatric consultation; there were complaints like inability to breathe, sweating, palpitations, reluctance, pessimism and unhappiness. The patient has diagnosed according to DSM IV-TR as “Agoraphobia without panic disorder” and “Major Depression, Single Episod”. Escitolopram titrated by 20 mg/day has started. Depressive and agoraphobic symptoms have disappeared at the end of four weeks (HAM-A-D:24;11-21;9). Discussion MG patients, especially during the beginning of disease symptoms in almost all patients with the appeal was referred to the psychiatric services and 1/3 of it has been reported as psychiatric mis-diagnosis [1,2]. Choice of psychotropic drugs is important that do not affect the respiratory center and neuromuscular transmission. Agents, used in the treatment of MG, can inflame psychopathology and can create resistance to psychotropic treatment. Therefore, cooperation of neurologist and psychiatrist is important.
Objective: Aggression is a particular problem commonly observed in personality disorders, especially in antisocial personality disorder (APD). It is well known that APD is closely related to substance use disorder (SUD). Individuals with higher aggression levels have also been suggested to have higher rates of SUD. The aim of this study is to investigate aggression levels and substance use characteristics of APD subjects with and without violent criminal behavior. Method: A total of 124 male subjects with APD consecutively admitted to the Forensic Psychiatry Department of GATA Haydarpasa Training Hospital were involved in the study. All subjects were evaluated with an assessment battery using a semistructured interview for socio-demographic, APD, and substance use characteristics, APD section of SCID-II, SCID-I, and Aggression Questionnaire. The sample was divided into 2 groups in terms of having a history of violent criminal behavior and compared correspondingly. Results: Of the APD subjects, 90.3 % reported a lifetime history of substance abuse and 75.8 % had a current co-diagnosis of SUD. APD subjects with violent criminal behavior were more likely to be diagnosed with SUD as compared to those with out violent crimes. Moreover, APD subjects with SUD had higher aggression levels than those without SUD. Conclusion: Our results indicate that substance use may mediate the association between APD and aggression. Therefore, the treatment of substance abuse in APD subjects is an important target particularly for prevention of violent criminal behaviors.