Mücahit Furkan Balcı

Sağlık Bilimleri Üniversitesi

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Murat Alan

Sağlık Bilimleri Üniversitesi

MŞ

Muzaffer Şancı

Izmir University

Celal Akdemir

Sağlık Bilimleri Üniversitesi

Yasemin Alan

Istanbul Metropolitan Municipality

ÖE

Özgür Erdoğan

Izmir Tepecik Eğitim ve Araştırma Hastanesi

Pınar Tuğçe Özer

Ministry of Health

AÖ

Alp Özgüzer

Izmir Tepecik Eğitim ve Araştırma Hastanesi

BÖ

Bayram Özağaç

HŞ

Hilal Şahin

Sağlık Bilimleri Üniversitesi

Mehmet Simsar

Istanbul Medipol University

Cooperative Institutions

Sağlık Bilimleri Üniversitesi

Izmir Tepecik Eğitim ve Araştırma Hastanesi

Izmir University

University of Health Science

University of Health Sciences

Universidad CES

Ministry of Health

Yenişehir Hospital

Izmir Kâtip Çelebi University

Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi

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Metastasis of endometrial cancer to breast: A rare case

Journal of Obstetrics and Gynaecology Research (2023)

Özgür Erdoğan Mücahit Furkan Balcı Alp Özgüzer Emel Özdaş Gökşen Görgülü

Only 2% of all breast cancers are metastatic, making them extremely uncommon. They are frequently mistaken for a primary breast tumor. Although it has been observed, metastatic spread from primary uterine cancers is extremely uncommon. In the literature, our case represents the fourth endometroid adenocarcinoma metastasis from the uterus. Clinical, pathological, and immunohistochemical examination and management of metastatic endometrioid adenocarcinoma of the uterus' extragenital organ were described in this 69-year-old patient's case. Immunohistochemical analysis was performed on a breast biopsy taken from the patient who underwent therapy and discovered a breast mass two years later. Metastatic endometrial adenocarcinoma was diagnosed with negative signs pointing to mammaglobin, GCDFP-15 and GATA3 breasts and markers indicating endometroid adenocarcinomas such as p53, PAX8 and VIMENTIN support. As a result, a thorough clinical history is needed, with special attention to diagnoses of concurrent or prior malignancies, along with clinical examination, appropriate radiological evaluation, and immunohistochemistry. This is necessary to prevent unnecessary surgery, to provide appropriate systemic treatment, to ensure correct diagnosis, and to manage treatment.

Mammaglobin

10.1111/jog.15621

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Recurrent hydatidiform moles: detection of a new mutation in the NLRP7 gene in the family

International Journal of Reproduction Contraception Obstetrics and Gynecology (2023)

Mücahit Furkan Balcı Özge Özer Kaya Atakan Emre Gezici Serkan Oral Yaşam Kemal Akpak

Hydatidiform moles are the most common type of gestational trophoblastic neoplasia. Hyperproliferative vesicular trophoblasts and imperfect fetal development are abnormal pregnancies, and recurrent hydatidiform moles are rare. Mutations in NLRP7 are responsible for recurrent hydatidiform mole. Genetic heterogeneity has been demonstrated in patients with the NLRP7 mutation. This study presents our case with gravida 11, parity 0, histopathologically diagnosed with six hydatidiform moles and five missed abortion histories at age 35. Karyotype analyses of the unrelated couple were normal. A genetic examination revealed a novel mutation of the NLRP7 gene in the patient, his brother, and his parents. Detecting a new NLRP7 mutation in recurrent hydatidiform moles cases provides further evidence for the predetermined role of NLRP7 mutations in the pathophysiology of recurrent moles hydatidiform. Based on our findings, we hope to contribute to the literature by expanding the spectrum of recurrent pregnancy loss associated with NLRP7 mutations in patients.

Partial Hydatidiform Mole

10.18203/2320-1770.ijrcog20231943

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Is It Time To Revise Cervical Cancer Screening Guidelines?

International Journal of Gynecological Cancer (2025)

Celal Akdemir Mücahit Furkan Balcı Ali Onur Arzik Serkan Karaoğlu Gönül Şimşek

10.1016/j.ijgc.2024.101274

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Early Surgical Complications Following Radical Hysterectomy: A Single Centre Experience

International Journal of Gynecological Cancer (2025)

Celal Akdemir Mücahit Furkan Balcı Özgür Erdoğan Zeliha Öcal Murat Alan

10.1016/j.ijgc.2024.100505

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HPV 16 pozitif vakaların değerlendirilmesi

DergiPark (Istanbul University) (2024)

Yiğit Yüksel Yasemin Alan Mücahit Furkan Balcı Murat Alan

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Retrospective Analysis of the Efficacy and Safety of Benign Gynecological Laparoscopic Surgery in Patients with a History of Open Abdominal Surgery

Sabuncuoglu Serefeddin Health Sciences (2024)

Mukadder Şanlı Mücahit Furkan Balcı Bayram Özağaç Yasemin Alan Murat Alan

Objective : In our clinic, we aim to analyze the operative characteristics and complications of patients who have undergone abdomen surgery prior to total laparoscopic hysterectomy, in comparison to those who have not. Materials and Methods: The study analyzed a total of 2012 cases of laparoscopic hysterectomy conducted at the Women's Diseases and Birth Clinic in Tepecik Training and Research Hospital from January 2021 to December 235. The cases were categorized based on whether the patients had previous abdominal surgery or not. Various demographic characteristics, surgical treatment methods, operation durations, indications for hysterectomy, and postoperative findings were documented. Statistical analysis was performed using the SPSS program, with a significance level set at P < 0.05. Findings :No significant differences were found between the two groups in terms of age, body mass index (BMI), preoperative and postoperative hemoglobin (Hb) values and values. In contrast, the difference between preop and post op Hb value measurements ; the level of statistically significant is higher in the group without obdomen surgery (p=0,001). There is no statistically significant difference between indications in both groups as surgical indication (p=0,043). In the group without western surgery, adhesion was observed to be statistically significantly lower (p=0,001). In the group with abdomen surgery, the presence of adhesions sufficient to require adezyolisis is statistically significant (p

Gynecological surgery

10.55895/sshs.1591946

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Evaluation of maternal and neonatal outcomes of emergency cesarean deliveries in cases of placenta previa uncomplicated with placenta acreata spectrum

Aegean Journal of Obstetrics and Gynecology (2023)

Mehmet Özer Pınar Tuğçe Özer Alper İleri Barış Sever Onur Süleyman Aldemir

Objective: The management and surgery of placenta previa describe a challenging process that requires experience. It is important to decide on the timing of planned cesarean section in women with placenta previa, taking into account the balance between possible maternal severe bleeding and possible neonatal morbidities. Material and methods: In the present study, the data of 349 singleton pregnant women with a diagnosis of placenta previa uncomplicated by placenta accreta spectrum were analyzed. Patients who underwent planned (68%, n=236) or emergency cesarean section (32%, n=113) were divided into two groups. In this study, maternal demographic and clinical information, surgical procedures and maternal/neonatal outcomes were studied. Results: The proportion of patients who underwent uterine compression suture and Bakri balloon was found to be significantly higher in the emergency cesarean section group compared to the planned cesarean deliveries group (p<0.001). The operation time, hospital stay, urinary tract infection rate, decrease in hemoglobin and need for blood transfusion were found to be significantly higher in the emergency cesarean section group compared to the planned cesarean section group (p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, p<0.001, respectively). In addition, a significant association was detected between emergency cesarean section and prematurity, low birth weight, low APGAR score, increased neonatal intensive care unit hospitalization and neonatal mortality. Conclusion: Cases of placenta previa are at risk of emergency cesarean delivery, which can be complicated by poor maternal and neonatal outcomes. Equipped centers and experienced teams are of great importance in reducing fetomaternal morbidity and mortality caused by placenta previa.

Placenta previa

Apgar score

Placenta Accreta

10.46328/aejog.v5i2.159

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Are serum calcium and vitamin D levels effective in osteoporosis?

DergiPark (Istanbul University) (2024)

Mustafa Cihan Baysal Murat Alan Yasemin Alan Mücahit Furkan Balcı Emrah Töz

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The relationship between imaging‐based body composition parameters and disease prognosis in patients with endometrial cancer

Journal of Obstetrics and Gynaecology Research (2024)

Elçin Aydın Ezgi Güvel Verdi Mücahit Furkan Balcı Begüm Ergin Yeşim Yekta Yürük

Obesity is known as a risk factor for endometrial cancer (EC). Only a few studies investigate the relationship between sarcopenia and sarcopenic obesity and EC. In this study, our aim was to investigate the relationship between the cross-sectional imaging-based body composition parameters and the disease prognosis in low-grade (LG) and high-grade (HG) EC.

10.1111/jog.16010

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