Laura Cassar

Garrahan Hospital

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Natalio Fejerman

Garrahan Hospital

Ariel Sologuestua

Garrahan Hospital

Roberto Caraballo

Garrahan Hospital

Ricardo Cersósimo

National University of Lomas de Zamora

Roberto Caraballo

Garrahan Hospital

Isaac Iván Yépez

A. Yerga

Garrahan Hospital

Hugo Pomata

Garrahan Hospital

Soledad Monges

Garrahan Hospital

H Arroyo

Garrahan Hospital

Cooperative Institutions

Garrahan Hospital

University of Verona

Hospices Civils de Lyon

Hôpital Femme Mère Enfant

Azienda Ospedaliera Universitaria Integrata Verona

University of Modena and Reggio Emilia

Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia

Meyer Children's Hospital

Children's Hospital

Instituto de Neurología de Buenos Aires

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Encefalopatía sarampionosa subaguda retardada

Revista de Neurología (2003)

Roberto Caraballo Soledad Monges Ricardo Cersósimo Laura Cassar Isaac Iván Yépez

We analyze the clinical, neurological, EEG, neuroradiological features and evolution of two patients with subacute measles encephalitis.The patients, aged five years and eleven months respectively showed an acute, progressive neurological compromise and deterioration of consciousness, epilepsia partialis continua and progressive damage on neuroimaging, with a history of measles in the first case and exposure to the virus in the second. The first patient had Hodgkin's disease and the other had a familial C4 deficit disorder. Fundoscopic examination showed lesions on the retina. The EEG showed unilateral slow waves and spikes. Brain CT and MRI revealed progressive cerebral atrophy and a unilateral corticosubcortical lesion. Measles antibodies in CSF were found in the first child and oligoclonal bands in the second. Our first patient died after three months and the second has a severe neurological damage.In immunocompromised patients with the exposure to a history of measles, acute neurological compromised and deterioration of consciousness, epilepsia partialis continua and progressive damage on neuroimaging, subacute measles encephalitis should be considered.

Epilepsia partialis continua

Subacute sclerosing panencephalitis

10.33588/rn.3704.2002462

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Citations (3)

SEVERE ACUTE ENCEPHALOPATHY WITH EXTRAPYRAMIDAL INVOLVEMENT OF UNKNOWN ETIOLOGY

Neuropediatrics (2006)

HA Arroyo Soledad Monges Laura Cassar Liliana Czornyj Víctor Ruggieri

Objectives: Objectives: We describe the clinical features and evolution of six patients with acute encephalopathy (AE) with extrapyramidal involvement and of unknown etiology.

Etiology

Extrapyramidal symptoms

Extrapyramidal disorder

10.1055/s-2006-945699

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Citations (0)

Complications during invasive Video-EEG monitoring in children and adolescents with epilepsy

Clinical Neurophysiology (2008)

Carlos Medina C. Pociecha Laura Cassar H. Lee Ariel Sologuestua

10.1016/s1388-2457(08)60643-4

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Migrating Focal Seizures in Infancy: Analysis of the Electroclinical Patterns in 17 Patients

Journal of Child Neurology (2008)

Roberto Caraballo Elena Fontana Francesca Darra Laura Cassar Francesca Negrini

We describe the electroclinical features, therapy, and long-term evolution of 17 patients with migrating focal seizures in infancy, and analyzed the charts of these patients seen between February 1985 and July 2005. Three different electroclinical patterns were recognized: (1) 8 cases with alternating simple focal motor seizures at onset. The ictal electroencephalography (EEG) pattern was characterized by recurrence of rhythmic focal spikes or rhythmic sharp activity in the Rolandic region; (2) 5 cases with complex focal seizures and progressive appearance of polymorphic δ-θ activity in 1 temporo-occipital region recurring independently; (3) 4 cases with focal complex seizures with motor manifestations. Ictal EEG showed flattening or fast activity in 1 frontotemporal region followed by unilateral fast poly-spikes in alternating clusters in both hemispheres. The focal seizures were refractory to antiepileptic drugs, and all patients except 3 had severe developmental delay. Migrating focal seizures in infancy is a newly defined and rare, but underrecognized, epileptic encephalopathy.

Epileptic spasms

10.1177/0883073807309771

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Citations (56)

Epilepsia mioclónica refleja del lactante

Revista Ecuatoriana de Neurologia (1998)

Roberto Caraballo Laura Cassar S Monjes Isaac Iván Yépez Santiago Galicchio

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Síndrome de Angelman: Características electroclínicas en 35 pacientes

Revista de Neurología (2003)

Ricardo Cersósimo Roberto Caraballo Alberto Espeche Laura Cassar María Torrado

The purpose of this study is to report on 35 patients with Angelman syndrome (AS) in whom we evaluated the electroclinical characteristics and the progression of their epilepsy.The following factors were evaluated: sex, family background, neurological examination, age at onset and semiology of the epileptic seizures, EEG, types of epilepsy according to the international classification and response to therapy. We investigated the karyotype, and conducted FISH and methylation tests for AS.The 35 patients had an average follow up time of 5.6 years. Epilepsy was diagnosed in 25 cases, with an average age of onset of 1.6 years. The epileptic syndromes were: epilepsy with myoclonic seizures in 13, of which seven presented a myoclonic state in their history, focal epilepsy in seven, West's syndrome in three, and Lennox Gastaut syndrome in two. Intercritical EEG showed generalised MSW and SW paroxysms in 13, unilateral spikes in seven, hypsarrhythmia in three, generalised fast rhythm paroxysms and slow SW activity in two. Basal electroencephalographic activity was: slow hypervoltage waves with or without inserted spikes situated at the rear in 19, at the front in six, diffuse in six, and normal in four cases.71.4% of patients with AS suffered epileptic seizures; epilepsy with myoclonic seizures was the most frequently observed epileptic syndrome and hypervoltage slow wave activity with or without spikes inserted in the posterior quadrants was a characteristic encephalographic pattern. In patients with mental retardation, with or without epilepsy and these electroencephalographic findings, even in the absence of characteristic clinical signs, methylation and FISH analyses for AS should be performed.

Hypsarrhythmia

Angelman Syndrome

West Syndrome

Myoclonic epilepsy

10.33588/rn.3701.2003109

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Citations (10)

Usefulness of intracranial electrodes in Frontal Refractory Epilepsy in childhood

Clinical Neurophysiology (2008)

Ariel Sologuestua Juan Pociecha Laura Cassar Alfonso Medina Hugo Pomata

Refractory (planetary science)

Childhood absence epilepsy