Giampaolo Cengia

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

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Claudio Simeone

University of Brescia

N. Mantovani

Azienda Ospedaliera Carlo Poma

A. Benedetti

Marche Polytechnic University

ML Canfora

University of Cagliari

Alessandro Repici

IRCCS Humanitas Research Hospital

M Bassi

Laura Lamonaca

Humanitas Mater Domini

E. Di Giulio

Azienda Ospedaliera Sant'Andrea

C Calcara

Santissima Trinità

Chiara Alvisi

Policlinico San Matteo Fondazione

Cooperative Institutions

Istituti di Ricovero e Cura a Carattere Scientifico

Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

RELX Group (Netherlands)

University of Brescia

University of Bologna

University of Parma

University of Milan

Brescia University

IRCCS Humanitas Research Hospital

Marche Polytechnic University

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Endoscopy (2020)

Alessandro Fugazza Laura Lamonaca Chiara Alvisi Giovanni Aragona M. Ayoubi

Aims ERCP is performed with reusable duodenoscopes after manual and automated reprocessing. Recently, multidrug-resistant infection outbreaks associated with infected duodenoscopes have been reported. Our aim was to investigate the current Italian experience with duodenoscope-related infections and assess the criticality of the risk.

10.1055/s-0040-1704233

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Gastrointestinal hemorrhage and gynecomastia as first signs of metastatic testicular choriocarcinoma

Case Reports in Internal Medicine (2014)

Marianna Salemme Riccardo Nascimbeni Andrea Tironi Regina Tardanico Giampaolo Cengia

Testicular choriocarcinoma is an infrequent non seminomatous germ cell tumor, usually presenting histologically as part of a mixed germ cell tumor, and rarely as pure form. It metastasizes early, usually along hematogenous routes, lungs being the most frequent sites of metastasis. Involvement of the gastro-intestinal tract as metastatic site is extremely uncommon and rarely described in the literature. We report the case of a 47 year-old male with gastric and pulmonary metastases from testicular mixed germ cell tumor mainly represented by choriocarcinoma as histological subtype, presenting with melena and gynecomastia as first clinical signs. Morphological and immunohistochemical analyses of biopsies taken from the endoscopically identified gastric hemorrhagic lesion and from lung nodules showed undifferentiated neoplastic epithelial cells in a necrotic and hemorrhagic background. Coexistence of gynecomastia addressed towards an hormonal-dependent tumor and prompted us to apply further morphological and immunohistochemical analyses, revealing the gonadal primary neoplasm, subsequently confirmed at surgery.

Gynecomastia

Metastatic carcinoma

Neoplasm

10.5430/crim.v1n2p92

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Citations (1)