M. Wang

Huazhong University of Science and Technology

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H. Wang

Nanjing Normal University

Mingzhe Han

Institute of Hematology & Blood Diseases Hospital

Minmin Wang

Nantong University

Ai Guo

Huazhong Agricultural University

Xiaolan Yang

Guiyang Medical University

Di Wu

Huazhong University of Science and Technology

T. Chen

Huazhong University of Science and Technology

Yufei Shi

University of Science and Technology of China

Li Zhang

South China University of Technology

Lunli Zhang

First Affiliated Hospital of Nanchang University

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Huazhong University of Science and Technology

Tongji Hospital

First Affiliated Hospital of Jiangxi Medical College

Shanghai Jiao Tong University

Capital Medical University

Sichuan University

Chinese Academy of Medical Sciences & Peking Union Medical College

Peking University

Xiamen University

China Academy of Engineering Physics

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Molecular Adsorbent Recirculating System: clinical experience in patients with liver failure based on hepatitis B in China

Liver International (2002)

S Chen Li Zhang Yufei Shi Xiaolan Yang M. Wang

Abstract: The aim of this study is to evaluate the effect of treatment with the Molecular Adsorbent Recirculating System (MARS) on liver failure based on HBV. In 25 patients (median age, 36.3 years, range, 22–67 years, bilirubin level > 255 µmol/l) admitted with liver failure based on HBV, the 6–8h MARS intermittent treatments were performed without any adverse events, A significant decrease in bilirubin, ammonia and urea levels were observed ( P < 0.05). All patients achieved a remarkable neurologic recovery, particularly 2 HE‐III and 3 HE‐IVpatients regained normal consciousness, respectively. The survival rate for the patients whose treatments kept to the MARS art strategy was 76.9% (10/13), while the others only had the survival rate of 16.7% (2/12) due to their giving up sequential MARS treatments after the first time. The rebounding rate of the bilirubin level in the patients after a single MARS treatment was significantly lower than that of patients, who underwent a single plasma‐exchange treatment ( P < 0.01). It is concluded that MARS method can contribute to the optimistic treatment of liver failure patients based on HBV which being the major epidemic liver disease in China.

Liver disease

Hepatitis B

10.1034/j.1600-0676.2002.00009.x

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1116 A DISPARATE SUBSET OF DOUBLE NEGATIVE T CELLS CONTRIBUTES TO THE OUTCOME OF MURINE FULMINANT VIRAL HEPATITIS VIA EFFECTOR MOLECULE FIBRINOGEN-LIKE PROTEIN 2

Journal of Hepatology (2011)

H. Wang Di Wu T. Chen Yong Zou Weiming Yan

Fulminant

Fulminant hepatitis

10.1016/s0168-8278(11)61118-5

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