Kohei Nozaki

Kitasato University Hospital

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i-10 index

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Co-Authors

Emi Maekawa

Kitasato University

114

Kentaro Kamiya

Kitasato University

107

Nobuaki Hamazaki

Kitasato University Hospital

102

Minako Yamaoka‐Tojo

Nara Medical University

Junya Ako

Kitasato University

Atsuhiko Matsunaga

Kitasato University

Masashi Yamashita

Kitasato University

Ryota Matsuzawa

Hyogo University

Shota Uchida

Kitasato University

Takafumi Ichikawa

Kitasato University Hospital

Cooperative Institutions

University of Washington

138

University of Nebraska Medical Center

124

University of California, Irvine Medical Center

120

Seattle Cancer Care Alliance

119

Sheffield Teaching Hospitals NHS Foundation Trust

118

Fred Hutch Cancer Center

115

Kitasato University

114

Levine Cancer Institute

101

The University of Texas MD Anderson Cancer Center

Kitasato University Hospital

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Leg strength and incidence of heart failure in patients with acute coronary syndrome

European Journal of Preventive Cardiology (2023)

Kensuke Ueno Kentaro Kamiya Nobuaki Hamazaki Kohei Nozaki Takafumi Ichikawa

The risk of developing heart failure (HF) after acute coronary syndrome (ACS) remains high. It is unclear whether skeletal muscle strength, in addition to existing risk factors, is a predictor for developing HF after ACS. We aimed to clarify the relationship between quadriceps isometric strength (QIS), a skeletal muscle strength indicator, and the risk of developing HF in patients with ACS.

10.1093/eurjpc/zwad406

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Citations (5)

Increase in leg strength after outpatient cardiac rehabilitation contributes to improvement of gait speed in patients aged 75 years or older with cardiovascular disease

Japanese Physical Therapy Association (2017)

Nobuaki Hamazaki Kentaro Kamiya Ryota Matsuzawa Kohei Nozaki Shinya Tanaka

10.14900/cjpt.2016.1160

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Citations (0)

Effects of electrical muscle stimulation on physical function in frail older patients with acute heart failure: a randomized controlled trial

European Journal of Preventive Cardiology (2022)

Shinya Tanaka Kentaro Kamiya Yuya Matsue Ryusuke Yonezawa Hiroshi Saito

With the aging of the world's population, frailty, defined as reduced physiological reserve and vulnerability to stressors, is becoming an increasingly important issue in cardiovascular medicine in older patients.1,2 Acute heart failure (AHF) is a leading cause of hospitalization worldwide and is associated with frailty, reduced quality of life (QOL), and increased medical costs.3 In older AHF patients, frailty is a strong predictor of early disability, re-admission, and mortality.4 Electrical muscle stimulation (EMS) is a method of safely inducing muscle contraction that does not require volitional effort on the part of the patient and does not evoke dyspnoea.5 Short-term lower limb EMS was suggested to improve muscle strength, exercise capacity, and health-related QOL in hospitalized heart failure (HF) patients, these studies included few older patients.6,7 We performed a multicentre, randomized controlled trial called The Effects of Acute Phase Intensive Electrical Muscle...

Stressor

10.1093/eurjpc/zwac022

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Citations (16)

Development of an infection screening system for entry inspection at airport quarantine stations using ear temperature, heart and respiration rates

Guanghao Sun Nobujiro Abe Youhei Sugiyama Quang Vinh Nguyễn Kohei Nozaki

After the outbreak of severe acute respiratory syndrome (SARS) in 2003, many international airport quarantine stations conducted fever-based screening to identify infected passengers using infrared thermography for preventing global pandemics. Due to environmental factors affecting measurement of facial skin temperature with thermography, some previous studies revealed the limits of authenticity in detecting infectious symptoms. In order to implement more strict entry screening in the epidemic seasons of emerging infectious diseases, we developed an infection screening system for airport quarantines using multi-parameter vital signs. This system can automatically detect infected individuals within several tens of seconds by a neural-network-based discriminant function using measured vital signs, i.e., heart rate obtained by a reflective photo sensor, respiration rate determined by a 10-GHz non-contact respiration radar, and the ear temperature monitored by a thermography. In this paper, to reduce the environmental effects on thermography measurement, we adopted the ear temperature as a new screening indicator instead of facial skin. We tested the system on 13 influenza patients and 33 normal subjects. The sensitivity of the infection screening system in detecting influenza were 92.3%, which was higher than the sensitivity reported in our previous paper (88.0%) with average facial skin temperature.

Thermography

Respiration rate

Vital signs

Infection rate

10.1109/embc.2013.6611097

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Citations (18)

Association between sarcopenia and atherosclerosis in elderly patients with ischemic heart disease

Heart and Vessels (2020)

Shota Uchida Kentaro Kamiya Nobuaki Hamazaki Ryota Matsuzawa Kohei Nozaki

Arteriosclerosis

10.1007/s00380-020-01554-8

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Citations (43)

Association of sarcopenia defined by different skeletal muscle mass measurements with prognosis and quality of life in older patients with heart failure

Journal of Cardiology (2023)

Kaoru Sato Kentaro Kamiya Nobuaki Hamazaki Kohei Nozaki Takafumi Ichikawa

Bioelectrical Impedance Analysis

10.1016/j.jjcc.2023.12.003

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Citations (3)

Abstract 19966: Supervised Aerobic Exercise After Hospital Discharge Improves Pulmonary and Respiratory Muscle Function in Patients With Chronic Heart Failure

Circulation (2016)

Nobuaki Hamazaki Takashi Masuda Kentaro Kamiya Ryota Matsuzawa Kohei Nozaki

Background: Impaired pulmonary and respiratory muscle function is known to deteriorate the clinical outcome in patients with chronic heart failure (CHF). Exercise training was documented to improve exercise capacity, quality of life and prognosis in these patients. However, the effects of exercise training on pulmonary and respiratory muscle function are still controversial. We investigated the influence of supervised aerobic exercise on pulmonary and respiratory muscle function in CHF patients. Methods: We followed up 494 patients with compensated CHF (64.3±0.6 years, 337 males) for 5 months. All patients received cardiac rehabilitation consisted of supervised aerobic exercise during hospitalization. We measured forced vital capacity (FVC) and forced expiratory volume in 1 second (FEV 1 ) to evaluate pulmonary function. We also measured maximal inspiratory pressure (PI max ) as respiratory muscle strength. All parameters were measured before and after the 5-month observation period. Patients were divided into three groups based on the frequency of supervised aerobic exercise sessions after hospital discharge: group A (no sessions), group B (1-3 sessions per month) and group C (4 sessions per month or more). We examined the percentage change in the respiratory parameters from baseline to those after the observation period and compared these variables among the three groups using ANCOVA with adjustment for potential confounding factors. Results: In all the patients, FVC, FEV 1 and PI max increased significantly after the observation period as compared with each baseline (P max as compared with group A (Figure). The %change FEV 1 of group C was significantly higher than that of the other two groups (P=0.008 vs group A and P=0.047 vs group B). Conclusion: Supervised aerobic exercise after hospital discharge improved pulmonary and respiratory muscle function in patients with CHF.

Vital capacity

Aerobic Exercise

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Optimal cutoff values for physical function tests in elderly patients with heart failure

Scientific Reports (2022)

Keita Aida Kentaro Kamiya Nobuaki Hamazaki Kohei Nozaki Takafumi Ichikawa

Six-minute walk distance (6MWD) of 300 and 400 m are important targets of functional capacity. The present study was performed to determine cutoff values of physical function associated with 6MWD < 300 m and < 400 m in elderly patients with heart failure (HF). 6MWD, handgrip strength, quadriceps isometric strength (QIS), one-leg standing time (OLST), and 5-times sit-to-stand (5STS) before hospital discharge were evaluated in 1001 patients > 65 years (median age, 75: interquartile range, 71-80, 607 men) with HF. 6MWD < 300 and < 400 m were seen in 323 patients (32.3%) and 658 patients (65.7%), respectively. Handgrip strength, QIS, OLST, and 5STS were associated with 6MWD < 300 and < 400 m, respectively (P < 0.001). The cutoff values of handgrip strength, QIS, OLST, and 5STS were 18.9 kg, 35.0% body mass (BM), 9.1 s, and 9.5 s for 6MWD < 300 m, and 21.9 kg, 40.0% BM, 12.0 s, and 8.8 s for < 400 m, respectively. The cutoff values of physical function could be used to set cardiac rehabilitation goals and limiting determinants of reduced functional capacity in a clinical setting in elderly patients with HF.

Cut-off

Interquartile range

Limiting

10.1038/s41598-022-10622-0

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Citations (5)

The Association between the Level of Ankle-Brachial Index and the Risk of Poor Physical Function in Patients with Cardiovascular Disease

Journal of Atherosclerosis and Thrombosis (2023)

Shota Uchida Kentaro Kamiya Nobuaki Hamazaki Kohei Nozaki Takafumi Ichikawa

Aims: The progression of atherosclerosis and decline in physical function are poor prognostic factors in patients with cardiovascular disease (CVD). The ankle–brachial index (ABI) is a widely used indicator of the degree of progression of atherosclerosis, which may be used to identify patients with CVD who are at risk of poor physical function. This study examined the association between ABI and poor physical function in patients with CVD.

Interquartile range

10.5551/jat.64531

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Citations (2)

Gait speed has comparable prognostic capability to six-minute walk distance in older patients with cardiovascular disease

European Journal of Preventive Cardiology (2017)

Kentaro Kamiya Nobuaki Hamazaki Yuya Matsue Alessandro Mezzani Ugo Corrà

Background Although gait speed and six-minute walk distance are used to assess functional capacity in older patients with cardiovascular disease, their prognostic capabilities have not been directly compared. Methods The study population was identified from the Kitasato University Cardiac Rehabilitation Database and consisted of 1474 patients ≥60 years old with a mean age of 72.2 ± 7.1 years that underwent evaluation of both usual gait speed and six-minute walk distance in routine geriatric assessment between 1 June 2008–30 September 2015. Both gait speed and six-minute walk distance were determined on the same day at hospital discharge. Results Mean gait speed and six-minute walk distance in the whole population were 1.04 m/s and 381 m, respectively, and were strongly positively correlated ( r = 0.80, p < 0.001). A total of 180 deaths occurred during a follow-up of 2.3 ± 1.9 years. After adjusting for confounding factors, both gait speed (adjusted hazard ratio per 0.1 m/s increase: 0.87, 95% confidence interval: 0.81–0.93, p < 0.001) and six-minute walk distance (adjusted hazard ratio per 10-metre increase: 0.96, 95% confidence interval: 0.94–0.97, p < 0.001) were independent predictors of all-cause mortality. There was no significant difference in prognostic capability between gait speed and six-minute walk distance (c-index: 0.64 (95% confidence interval: 0.60–0.69) and 0.66 (95% confidence interval: 0.61–0.70), respectively, p = 0.357). Conclusions Gait speed and six-minute walk distance showed similar prognostic predictive ability for all-cause mortality in older cardiovascular disease patients, indicating the potential utility of gait speed as a simple risk stratification tool in older cardiovascular disease patients.

10.1177/2047487317735715

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Citations (120)