M Polyzonis

Theageneio General Hospital

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

P. Stravoravdi

Theageneio General Hospital

T. Toliou

Theageneio General Hospital

J. Hatzigiannis

A. Kortsaris

Democritus University of Thrace

Alfred Barich

Euromedica

P. Kirtsis

General Hospital of Drama

Th. Dimopoulos

J. Belivanis

Erotokritos Konstandinidis

General Hospital Asklepieio Voulas

Evdokimos Konstantinidis

Aristotle University of Thessaloniki

Cooperative Institutions

Aristotle University of Thessaloniki

Theageneio General Hospital

General Hospital of Drama

National and Kapodistrian University of Athens

Telio (Norway)

Democritus University of Thrace

National Centre of Scientific Research "Demokritos"

Interbalkan Medical Center

AHEPA University Hospital

Hellenic Cooperative Oncology Group

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

The influence of bromocriptine on the ultrastructure of the biceps femoris muscle in mice.

PubMed (1987)

P. Stravoravdi M Polyzonis T Demetriou

Bromocriptine and other dopaminergic agonists drugs are used in Parkinson's disease. In this paper we have studied the ultrastructure of striated muscle of mice after bromocriptine treatment. There was a tremendous increase in the number and size of mitochondria, as well as a very notable increase in the cristae. Some ultrastructure changes were also noted at the neuromuscular junctions. An explanation has been attempted in the light of other investigations concerning the relationship of microtubules and bromocriptine on the one hand, and microtubules and mitochondria on the other.

Source

Cite

Citations (0)

Fibroadenoma‐like foci in human prostatic nodular hyperplasia

The Prostate (1983)

P. M. Kafandari M Polyzonis

Abstract A morphologically distinctive lesion similar to fibroadenomas in female breast was found in 12 cases of benign prostatic hyperplasia out of 1356 prostatic specimens examined. All of them were from patients older than 60 years of age, and none from either normal or carcinomatous prostates. A possible pathogenetic interrelationship between the prostatic lesion and the fibroadenomas of female breast is discussed.

Breast Fibroadenoma

10.1002/pros.2990040104

Cite

Citations (9)

Abortion immunoregulatory il 2 and hla dr positive cells in the decidual lymphocytic infiltrate

Medical science research (1989)

Marïa Raptopoulou Gigi H Orphanou Koumerkeridou A Ganidis F Lagra M Polyzonis

Source

Cite

Citations (0)

Ultrastructural Study of the Noninvolved Urothelium of Tumor-Bearing Patients after Two Years of Intravesical Interferon Therapy

European Urology (1996)

P. Stravoravdi Konstantinos Natsis P. Kirtsis G. Retalis Erotokritos Konstandinidis

10.1159/000473800

Cite

Citations (8)

An ultrastructural study of cellular nuclei in a patient with scqamous cell carcinoma (SCC) before and after retinoids (Rs) and interferon (IFN) therapy

Cytokine (1994)

Alfred Barich P. Stravoravdi M Polyzonis

10.1016/1043-4666(94)90275-5

Cite

Citations (0)

Effect of bromocriptine on the ovarian cycle of two inbred strains of mice

Laboratory Animals (1987)

P. Stravoravdi T. Toliou M Polyzonis

Mice of the C3H/Sy (high incidence of spontaneous mammary cancer) and AKR/Sy (low incidence of spontaneous mammary cancer) inbred strains, which have different hormonal profiles, were injected daily with bromocriptine for 1 month. The treatment increased the duration of the ovarian cycle of the AKR/Sy mice, whereas that of the C3H/Sy mice was not affected. It is suggested that the effect of bromocriptine on the ovarian cycle depends on the concentrations of plasma progesterone reached in each strain of mouse.

Inbred strain

Strain (injury)

10.1177/002367728702100203

Cite

Citations (1)

The influence of age of culture on the morphology of T47D cells.

PubMed (1987)

P. Stravoravdi A. Kortsaris M Polyzonis

The cell line T47D is extensively used as model in studying the role of hormones in human breast cancer. On the other hand the study of their morphology is largely incidental and does not take into account the age of culture. We studied therefore the morphology of T47D cell line with the electron microscope from the third day of culture to the seventh without adding new medium and serum to find out if the age of culture affects their characteristics. Our results suggest that there is a constant change of the cell morphology and architecture. Thus some cell organelles as the nucleus, tonofilaments, endoplasmic reticulum, mitochondria and intercellular secretory ductules are affected by the age of culture. Also we observed signs of degeneration, necrobiosis and even necrosis on the seventh day of culture. These observations suggest that the age of culture of these cells should be taken into account in experiment planning.

Morphology

Organelle

Source

Cite

Citations (1)

The Ultrastructure of the Noninvolved Urothelium of Tumor-Bearing Patients Before and After Interferon Treatment

Journal of Interferon Research (1992)

P. Stravoravdi J. Belivanis Th. Dimopoulos J. Hatzigiannis M Polyzonis

The ultrastructural morphology of the noninvolved urothelium of tumor-bearing patients before and after interferon-α2b (IFN-α2b) treatment was investigated. The ultrastructure of the normal bladder urothelium has been reported. The noninvolved urothelium of our patients already showed deviation from the normal. At the end of therapy, we noted a partial restoration of the urothelium to its normal morphology with the reestablishment of some of its normal features, i.e., a well-developed Golgi apparatus, the existence of parts of the asymmetric unit membrane, and the appearance of nuclear bodies. Prevention of tumor recurrence by restoring the ultrastructural morphology of the noninvolved urothelium with IFN-α2b is a subject worthy of further investigation.

10.1089/jir.1992.12.397

Cite

Citations (3)

A New Approach Combining Interferon and Bromocriptine LA to Prevent Spontaneous Mouse Mammary Carcinoma

Journal of Interferon Research (1991)

P. Stravoravdi T. Toliou M Polyzonis

The development of spontaneous mammary carcinoma in C3H mice is mainly attributed to an oncogenic virus (MMTV) and the high prolactin levels of this inbred strain. Interferon (IFN) reduces the incidence of mammary carcinoma in virgin C3H mice when administered during lactation. Bromocriptine LA, an antiprolactin drug, also decreases the incidence of this tumor in C3H mice. The combined action of mouse IFN-α+β and bromocriptine LA had a significant anticarcinogenic effect more significant than either of the above agents administered independently. This antitumor action was effective in virgin C3H mice only.

Mammary carcinoma

Ratón

10.1089/jir.1991.11.49

Cite

Citations (0)

Nuclear bodies in liver metastases of an ileal carcinoid

Virchows Archiv (1971)

M Polyzonis M. Calpaksidis

Argentaffin

Pleomorphism (cytology)

Carcinoid tumour

Carcinoid tumors

10.1007/bf00548976

Cite

Citations (1)