Laura Moneghini

Ospedale San Paolo

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Giovanni Lodi

University of Milan

Niccolò Lombardi

University of Milan

Roberto Betti

Universidade de São Paulo

Elena Maria Varoni

University of Milan

A. Cerri

Ospedale San Paolo

Andrea Sardella

University of Milan

C. Crosti

University of Milan

S. Menni

University of Milan

Gaetano Bulfamante

University of Milan

Giacomo Colletti

University of Modena and Reggio Emilia

Cooperative Institutions

University of Milan

242

Ospedale San Paolo

141

Istituti di Ricovero e Cura a Carattere Scientifico

140

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

Azienda Socio Sanitaria Territoriale Santi Paolo e Carlo

Ospedale Maggiore

Ospedale San Paolo

Istituto Ortopedico Galeazzi

Vita-Salute San Raffaele University

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A rare case of transmural endometriosis in primary adenocarcinoma of the rectum.

PubMed (2014)

Monica Falleni David F. Bauer Enrico Opocher Laura Moneghini Gaetano Bulfamante

Intestinal endometriosis of the rectum and sigmoid colon, occurring in up to 34% of pelvic endometriosis, mimics a wide number of conditions that are difficult to differentiate from inflammatory or malignant diseases. Herein we report the first case of transmural endometriosis concomitant with advanced primary rectal adenocarcinoma, presenting with obstructive symptoms. Correct diagnosis based on morphological identification and immunohistochemical characterization of the two entities is crucial for treatment.

Concomitant

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Clinically and/or histologically pigmented poromas in Caucasian patients.

PubMed (2014)

Roberto Betti Caterina Bombonato A. Cerri Laura Moneghini P Abramo

Pigmented poromas are rarely reported and considered to be more common in non-white people and on non-acral sites. Objective of the present study was to report our cases of pigmented poromas with particular attention to the presence of clinical and/or microscopic evidence of pigmentation, their characteristics and the diagnostic pitfall with other pathologies.All the histologically confirmed poromas observed from January 1994 to July 2012 were considered. Clinic-epidemiological data were collected. The presence of clinical pigmentation was recorded as well as the presence of melanin pigmentation or melanocytes in the histologic specimens.One hundred and one patients with poromas were collected. All the patients were Caucasians. All the lesions were solitary. Only three patients had a clinically visible pigmented poromas. In eight cases the presence of melanin and melanocytes did not produce a clinically visible pigmentation. All the poromas with pigmentation did not occur on palmo-plantar surfaces.Pigmented poromas may be observed even in Caucasian patients and their clinical aspect mimic basal cell carcinoma and/or melanoma. The presence of pigment visible at the histology may not be observed in the clinical expression. The absence of pigmentation on palmo-plantar location is confirmed in all the reported cases.

Histology

Pigmentation disorder

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Growth rate of different basal cell carcinoma subtypes

European Journal of Dermatology (2017)

Roberto Betti Laura Moneghini E. Mapelli Gaetano Bulfamante A. Cerri

Basal cell carcinoma (BCC) subtypes appear to exhibit different biological behaviour [1, 2]. The speed of growth of tumours is one of the factors that can account for their tissue invasiveness. Interviewing patients is currently the only method of measuring the growth of a tumour over time [3, 4]. Few studies have investigated the speed of growth of BCC [5], moreover this has not been investigated in relation to the different BCC subtypes.Patients affected by BCCs were studied at our clinic between [...]

Basal (medicine)

10.1684/ejd.2017.3073

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CD10 and CD34 as markers in vascular malformations with PIK3CA and TEK mutations

Human Pathology (2020)

Laura Moneghini Delfina Tosi Daniela Graziani Anna Caretti Giacomo Colletti

10.1016/j.humpath.2020.04.001

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Solid Lipid Nanoparticles Topically Administered in Rabbits as New Drug Delivery System: A Preliminary Study of Safety and Bioavailability

Investigative Ophthalmology & Visual Science (2009)

Francesco Viola Chiara Mapelli Daniela Galimberti Gianluca Martini Roberto Esposti

Solid lipid nanoparticle

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A case of melanocytic matricoma with prominent mitotic activity and melanocytic hyperplasia

International Journal of Dermatology (2018)

Valentina Sangiorgio Laura Moneghini Delfina Tosi Gaetano Bulfamante

10.1111/ijd.14109

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Combined Endovascular and Surgical Treatment of Cervicofacial Arteriovenous Malformations

Otolaryngology (2014)

Giacomo Colletti Marco Mandalà Laura Moneghini Alice Frigerio Fabio Melchiorre

Objectives: Arteriovenous malformations (AVMs) often cause disfigurement and severe functional disturbances. An improper approach can unlock an explosive growth in the AVM and present a very high risk of relapse. Recurrent AVMs are much harder to cure. Intraoperative massive bleeding is a tangible risk if AVMs are treated surgically without preparatory endovascular embolization. The study's aims were: (1) Recognize and clearly diagnose a cervicofacial AVM. (2) Describe the indications and techniques to treat cervicofacial AVMs. (3) Analyze the critical importance of a combined endovascular and surgical approach. Methods: The most accepted indications and techniques concerning head and neck AVMs are gathered from a review of the literature and compared with the personal experience of the authors with 10 AVMs of the soft tissues of the head and neck and 4 AVMs of the facial bones. All patients underwent preoperative endovascular embolization with n‐butyl cyanoacrylate followed by surgical removal of the malformation within 48 hours of the procedure. Results: One early case of AVM of the maxilla was complicated by massive intraoperative hemorrhage despite preoperative embolization. One maxillo‐mandibular AVM recurred 2 years after the treatment. In all patients an improvement in cosmetic appearance was documented. Smaller AVMs were easier to manage and had the best results. Conclusions: An aggressive combined endovascular‐surgical treatment seems to be the only “curing” strategy for head and neck AVMs. A thoughtful preoperative balance must be made within a multidisciplinary team and clearly discussed with the patient.

Arteriovenous malformation

10.1177/0194599814541629a5

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Eccrine hamartoma with nevoid aspects on the forearm.

European Journal of Dermatology (2010)

Roberto Betti C. Crosti Laura Moneghini Caterina Bombonato S. Menni

Auteur(s) : Roberto Betti1, Carlo Crosti2, Laura Moneghini3, Caterina Bombonato1, Silvano Menni1 1Dermatologic Clinic, University of Milan, AO San Paolo, Milan, Italy, Via A Di Rudini 8, I-20142 Milan, Italy 2Dipartimento di Anestesiologia, Terapia intensiva e scienze dermatologiche, Universita degli studi di Milano - Fondazione IRCCS ca Granda - Ospedale maggiore policlinico, Milano, Italia 3Department of Medicine, Surgery and Dentistry, Division of Pathology, University of Milan, [...]

Hamartoma

10.1684/ejd.2010.1024

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Clinical and histopathological features of oral chronic graft-versus-host disease following allogeneic reduced-intensity conditioning haematopoietic stem cell transplantation : a single centre blind study

Federica Demarosi Davide Soligo Antonio Carrassi Francesco Onida Giovanni Lodi

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Within vascular malformations: histological confirmations and further aspects

Italian Journal of Vascular and Endovascular Surgery (2021)

Laura Moneghini A Zocca

INTRODUCTION: Vascular malformations (VMs) are rare vascular anomalies whose histological pattern suffer from obsolete and confusing terminology. Several histological classifications of VMs have been made starting with that of Virchow in the 19th century. Only in 1982 some authors distinguished VMs from other vascular anomalies such as benign vascular tumors, generally known as angiomas. Based on these data, in 1996 ISSVA (International Society for the Study of Vascular Anomalies) implemented a simple and multidisciplinary classification of vascular anomalies that also involves histological diagnosis. In this overview, we have studied the importance and effect of the ISSVA classification for the diagnosis, management and treatment of VMs.EVIDENCE ACQUISITION: We performed a research related to histological classification in two electronic databases (MEDLINE and Cochrane Library), without limitation on article type.EVIDENCE SYNTHESIS: We found 21 articles, 13 with a collection of cases and 8 with just a descriptive review. We reported the results on 374 collected cases of VMs, while we summarized the 8 descriptive reviews.CONCLUSIONS: In conclusion, the best histological classification appears the ISSVA Classification because it allows to join different specialists through a common language that is important for the best diagnosis, management and treatment of patients with VMs.

10.23736/s1824-4777.21.01486-8

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Citations (1)