Images are rich information carriers and (such as medical images) are normally contaminated by additive and substitutive noise which makes the extraction of features (and clinical data analysis) difficult.Hence to enhance the image quality prior to post processing, image pre-processing operations such as de-noising with linear and non-linear filters have been applied traditionally.Recently nonlinear filtering techniques have been assumed a lot of significance as they are capable of suppressing the effects of substitutive (salt and pepper impulsive noise of low to high noise levels) and additive (Gaussian noise of low to medium noise levels) noise types and to preserve the important signal/image details such as edges and fine details and suppress the degradations occurring at the time of image/signal formation or transmission through nonlinear channels, during storage and retrieval.Broadly speaking, image filters exist in transform and spatial domains.Spatial domain nonlinear filters are more versatile than their counterparts, namely linear filters.Spatial domain nonlinear fuzzy classical filters are simply modification/extension of the classical median and moving average filtering approaches, offer several advantages over classical nonlinear filters, and using simple fuzzy rules it is easy to realize them.They are also capable of reasoning with vague and uncertain information.Work presented in this paper deals with nonlinear median based and linear average based fuzzy filters and aims at fulfilling three objectives, viz; (i) To systematically study the performance of classical nonlinear median and fuzzy median and average filters for the removal of impulse and Gaussian noise from gray and color images that have been corrupted from low to high values of noise and to present an experimental review to identify the best algorithm within the frame work of classical fuzzy median filters.(ii)To propose : (a) an impulse classifier based fuzzy switching median filter and (b) the design of a multi pass cascaded fuzzy filter for noise cancellation, and explore their applications to reduce noise in images with random and impulse characteristics.Finally to conclude the work a comparative study is done and the computational aspects are analyzed with the help of mean square error (MSE), peak signal to noise ratio (PSNR), and 2D correlation (COR) and some future solutions are proposed.
With the increase in the VLSI technology level the system level designs are becoming too complex by effect of brutal design of low level complex design. The reduction in resources allocated to implement the system contributes to the significant decrease in the design complexity. In this paper, a new methodology is proposed for carry look-ahead adder to quarry the mitigation of resources required to implement the proposed adder. The implementation of the adder is carried on both Application Specific Integrated Circuit (ASIC) and Field Programmable Gate Array (FPGA) platforms. The proposed methodology presents the delay efficient adder simultaneously reducing the power consumption by decreasing the resources as its deliverables.
Orthopedicians often identify imaging modality visually out of their experience.To be effective, the process needs to be automated.This paper presents a behavior of wavelets in classification of orthopedic imaging modalities using Artificial Neural Network (ANN).In this work, we have considered orthopedic imaging modalities, namely, X-ray, CT and MRI and Bone scan images.Four wavelets, namely Haar, Daubechies, Symlets and Coiflets are used for sub band decomposition and their approximation co-efficients are recorded.Features, namely, mean standard deviation, median, variance and entropy is drawn from the decomposed images.Results are drawn from the performance of these wavelets at five levels of decomposition.Feature reduction is based on the classification accuracies which are analysed using wavelets.The experimental results show that the proposed method achieves satisfactory results with an average accuracy of 98% for four wavelets and for all the modalities considered.The study can be extended to include other modalities in medical field.The work is useful for orthopaedics practitioners.
Many different diseases can occur in the liver, including infections such as hepatitis, cirrhosis, cancer and over effect of medication or toxins. The foremost stage for computer-aided diagnosis of liver is the identification of liver region. Liver segmentation algorithms extract liver image from scan images which helps in virtual surgery simulation, speedup the diagnosis, accurate investigation and surgery planning. The existing liver segmentation algorithms try to extort exact liver image from abdominal Computed Tomography (CT) scan images. It is an open problem because of ambiguous boundaries, large variation in intensity distribution, variability of liver geometry from patient to patient and presence of noise. A novel approach is proposed to meet challenges in extracting the exact liver image from abdominal CT scan images. The proposed approach consists of three phases: (1) Pre-processing (2) CT scan image transformation to Neutrosophic Set (NS) and (3) Post-processing. In pre-processing, the noise is removed by median filter. The new structure is designed to transform a CT scan image into neutrosophic domain which is expressed using three membership subset: True subset (T), False subset (F) and Indeterminacy subset (I). This transform approximately extracts the liver image structure. In post processing phase, morphological operation is performed on indeterminacy subset (I) and apply Chan-Vese (C-V) model with detection of initial contour within liver without user intervention. This resulted in liver boundary identification with high accuracy. Experiments show that, the proposed method is effective, robust and comparable with existing algorithm for liver segmentation of CT scan images.
In general, it is known that an adaptive filter adjusts its parameters iteratively such as size of the working window, decision threshold values used in two stage detection-estimation based switching filters, number of iterations etc.It is also known that nonlinear filters such as median filters and its several variants are popularly known for their ability in dealing with the unknown circumstances.In this paper an efficient and simple adaptive nonlinear filtering scheme is presented to eliminate the impulse noise from the digital images with an impulsive noise detection and reduction scheme based on adaptive nonlinear filter techniques.The proposed scheme employs image statistics based dynamically varying working window and an adaptive threshold for noise detection with a Noise Exclusive Median (NEM) based restoration.The intensity value of the Noise Exclusive Median (NEM) is derived from the processed pixels in local neighborhood of a dynamically adaptive window.In the proposed scheme use of an adaptive threshold value derived from the noisy image statistics returns more precise results for the noisy pixel detection.The proposed scheme is simple and can be implemented as either a single pass or a multi-pass with a maximum of three iterations with a simple stopping criterion.The goodness of the proposed scheme is evaluated with respect to the qualitative and quantitative measures obtained by MATLAB simulations with standard images added with impulsive noise of varying densities.From the comparative analysis it is evident that the proposed scheme out performs the state-of-art schemes, preferably in cases of high-density impulse noise.
Abstract Liver segmentation is important to speed up liver disease diagnosis. It is also useful for detection, recognition, and measurement of objects in liver images. Sufficient work has been carried out until now, but common methodology for segmenting liver image from CT scan, MRI scan, PET scan, etc., is not available. The proposed methodology is an effort toward developing a general algorithm to segment liver image from abdominal computerized tomography (CT) scan and magnetic resonance imaging (MRI) scan images. In the proposed algorithm, pixel intensity range of the liver portion is obtained by cropping a random section of the liver. Using its histogram, threshold values are calculated. Further, threshold-based segmentation is performed, which separates liver from abdominal CT scan image/abdominal MRI scan image. Noise in the liver image is reduced using median filter, and the quality of the image is improved by sigmoidal function. The image is then converted into binary image. The Chan–Vese (C–V) model demands an initial contour, which evolves outward. A novel algorithm is proposed to identify the initial contour inside the liver without user intervention. This initial contour propagates outward and continues until the boundary of the liver is identified accurately. This process terminates by itself when the entire boundary of the liver is detected. The method has been validated on CT images and MRI images. Results on the variety of images are compared with existing algorithms, which reveal its robustness, effectiveness, and efficiency.
Abstract Lung cancer is the most common and fatal type of cancer. NSCLC refers to any kind of epithelial lung cancer that isn't small cell lung cancer (SCLC), which results for 85 percent of lung cancer cases. Differential gene expression is a type of gene analysis in which the RNA sequence data from next-generation sequencing is shown for any quantitative changes in the experimental data set's levels. Transcriptome analysis focuses on obtaining transcript statistics from a gene transcript file with a fold change of genes on a normalised scale in order to find quantitative differences in gene expression levels between the reference genome and NSCLC samples. The data has a significant clinical influence in terms of identifying and characterising candidate genes in order to validate them. The resultant data set and the plot display depicts the significant candidate genes in the respective location which are significant in expressing their changes in samples of NSCLC. The samples are differentiated with prominent gene labels of NSCLC disease samples. The significant values of this quantized analysis on read count data of expression, data tables prompt the candidate genes data set of NSCLC samples also the results explain the differential expression of particular samples across samples from genders namely male and female. The current research experiment focuses on the computational difficulty of read, search, match, and data enrichment of unstructured data with the goal of classifying biomarkers based on differential expression results and pathways found by classification algorithms.
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