Philippe Schaeffer

Institut de Chimie de Strasbourg

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Pierre Adam

Institut de Chimie de Strasbourg

Stefano M. Bernasconi

ETH Zurich

Estelle Motsch

Centre National de la Recherche Scientifique

Pierre Albrecht

Académie de Paris

Vincent Grossi

Université de Toulon

P. Albrecht

Centre National de la Recherche Scientifique

Blandine Courel

British Museum

Jacques Connan

Université de Strasbourg

J.M. Trendel

Centre National de la Recherche Scientifique

Philippe Oger

Laboratoire de Microbiologie, Adaptation et Pathogénie

Cooperative Institutions

Centre National de la Recherche Scientifique

258

Université de Strasbourg

Institut de Recherche pour le Développement

Laboratoire d’Études en Géophysique et Océanographie Spatiales

Centre National d'Études Spatiales

Collecte Localisation Satellites (France)

Institut de Chimie de Strasbourg

Université Toulouse III - Paul Sabatier

Université de Toulouse

Institut National de Recherches Archéologiques Préventives

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Extreme euxinia just prior to the Middle Triassic biotic recovery from the latest Permian mass extinction

Organic Geochemistry (2014)

Ryosuke Saito Masahiro Oba Kunio Kaiho Philippe Schaeffer Pierre Adam

Early Triassic

Permian–Triassic extinction event

Green sulfur bacteria

Extinction (optical mineralogy)

Micrite

Bioindicator

10.1016/j.orggeochem.2014.05.007

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Citations (19)

14β,22R-epithiosteranes, a novel series of fossil steroids widespread in sediments

Tetrahedron Letters (1997)

Anke Behrens Philippe Schaeffer Pierre Albrecht

10.1016/s0040-4039(97)01059-9

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Citations (19)

Novel aromatic carotenoid derivatives from sulfur photosynthetic bacteria in sediments

Tetrahedron Letters (1997)

Philippe Schaeffer Pierre Adam Patrick Wehrung Pierre Albrecht

Green sulfur bacteria

10.1016/s0040-4039(97)10235-0

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Citations (85)

Biosynthesis of Isoprene Units in Euphorbia lathyris Laticifers vs. Other Tissues: MVA and MEP Pathways, Compartmentation and Putative Endophytic Fungi Contribution

Molecules (2019)

Clément Gastaldo Agata Lipko Estelle Motsch Pierre Adam Philippe Schaeffer

Euphorbia species are characterized by a net of laticifers producing large amounts of triterpenes. These hydrocarbon-like metabolites can be converted into fuel by the methods of the oil industry. Euphorbia lathyris is easily grown at an industrial scale. In an attempt to increase its triterpene production, the metabolic pathways leading to isoprenoid were investigated by incorporation of 13C labeled glucose and mevalonate and 2H labeled deoxyxylulose as well as by natural abundance isotope ratio GC-MS. Latex triterpenes are exclusively synthesized via the mevalonate (MVA) pathway: this may orient future search for improving the triterpene production in E. lathyris. Phytosterols and their precursors are mainly derived from MVA pathway with a slight contribution of the methylerythritol phosphate (MEP) pathway, whereas phytol is issued from MEP pathway with a minor contribution of the MVA pathway: this is in accordance with the metabolic cross-talk between cytosolic and plastidial compartments in plants. In addition, hopenol B behaved differently from the other latex triterpenes. Its 13C isotope abundance after incorporation of 13C labeled glucose and its natural abundance δ2H signature clearly differed from those of the other latex triterpenes indicating another metabolic origin and suggesting that it may be synthesized by an endophytic fungus.

Terpene

Metabolic pathway

Isoprene

Mevalonate pathway

Metabolic Engineering

Euphorbia

10.3390/molecules24234322

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Citations (7)

Organic substances from Egyptian jars of the Early Dynastic period (3100–2700 BCE): Mode of preparation, alteration processes and botanical (re)assessment of “cedrium”

Journal of Archaeological Science Reports (2017)

Mathilde Sarret Pierre Adam Philippe Schaeffer Quentin Ebert Julien Perthuison

Embalming

Steam distillation

Ancient Egypt

Cupressaceae

10.1016/j.jasrep.2017.06.021

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Citations (7)

The Werra cyclotheme (Upper Permian, Fore-Sudetic Monocline, Poland): Insights into fluctuations of the sedimentary environment from organic geochemical studies

Applied Geochemistry (2012)

Bartosz Kluska Mariusz J. Rospondek Leszek Marynowski Philippe Schaeffer

Phytane

Monocline

Sterane

10.1016/j.apgeochem.2012.09.010

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Citations (21)

Molecular Investigation of Archaeological Ambers from Alsace (Ne France): Origins and Alteration Processes

30th International Meeting on Organic Geochemistry (IMOG 2021) (2021)

Suzanne Schmitt Pasrun Adam Philippe Schaeffer Carlos Felíu N. Schneider-Schwien

Summary A set of amber samples collected from archaeological burials at three different sites in Alsace (NE France) and dated back to the Bronze Age and the high Middle Age, as well as European ambers from potential geological sources have been investigated. Based on GC-MS analysis of lipid biomarkers occurring in the solvent extract and of those released by chemical degradation which comprised various diterpenoids and succinates, it appears that the archaeological samples correspond to Baltic amber, confirming that the Baltic region was a source of amber for Alsace, at least during the Bronze Age and the High Middle Age. Identification of the source of ambers using lipid distributions was possible despite alteration of the molecular signatures by natural degradation processes.

Baltic amber

Archaeological Science

10.3997/2214-4609.202134073

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Citations (1)

Milk production in pottery. Evidence for various exploited resources used by the first farmers in Central Pyrenees using the morphological, chemical and stable carbon isotopic composition of organic residues from ceramic vessels

Archaeological and Anthropological Sciences (2024)

Nàdia Tarifa-Mateo R. Laborda Alejandro Sierra Lourdes Montes Pilar Utrilla

Isotope Analysis

Human settlement

10.1007/s12520-024-02001-9

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STRUCTURAL INVESTIGATION OF THE MACROMOLECULAR COMPONENT OF BALTIC AMBER BY SELECTIVE CHEMICAL DEGRADATION

30th International Meeting on Organic Geochemistry (IMOG 2021) (2021)

Sébastien Schmitt Philippe Schaeffer Pierre Adam C. Féliu N. Schneider-Schwien

Summary The constitution of Baltic amber, the role of succinic acid and, more generally, of ester bonds in the constitution of macromolecular components of amber has been further investigated by chemical degradation of the solvent insoluble part of Baltic amber using butanolysis (BuOH/HCl). Succinic acid derivatives were the sole compounds released upon butanolysis whereas other compounds which could correspond to the alcohol counterparts of succinates could not be detected by GC-MS. This result indicate that these counterparts are all located on high molecular weight structural moieties. Succinic acid thus plays a key role as cross-linking agent between oligomeric structural moieties based on diterpenoids necessarily bound by at least one non-hydrolysable C-O or C-C bond.

Succinic acid

Degradation

Succinates

10.3997/2214-4609.202134076

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Bacteriohopanepolyols in hydrothermal vent biogenic silicates

Organic Geochemistry (2005)

Helen M. Talbot Paul Farrimond Philippe Schaeffer Richard D. Pancost

Hot spring

10.1016/j.orggeochem.2004.10.015

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Citations (37)