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Ricardo Luiz Smith

Universidade Federal de São Paulo

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Iván Suazo Galdames

Universidad Autónoma de Chile

Luís Garcia Alonso

Central University Hospital of Asturias

Daniela Alejandra Zavando Matamala

University of Talca

Sérgio Ricardo Marques

Universidade Federal de São Paulo

Marco Antonio De Angelis

Hospital Santa Marcelina

Sadao Isotani

Universidade de São Paulo

Michel Eid Farah

Universidade Federal de São Paulo

Laís Vieira Bonaldi

Universidade Federal de São Paulo

José Carlos Prates

Universidade Federal de São Paulo

Ala S. Haddadin

Yale University

Cooperative Institutions

Universidade Federal de São Paulo

Universidade de São Paulo

Fundação de Apoio à Universidade Federal de São Paulo

Associação Paulista de Medicina

Union des Industries Ferroviaires Européennes

Johns Hopkins University

Instituto da Visão

Hospital São Paulo

Instituto Butantan

Universidad Autónoma de Chile

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The mgΔlpn mouse model for Marfan syndrome recapitulates the ocular phenotypes of the disease

Experimental Eye Research (2021)

Rodrigo Barbosa de Souza Isabela Gerdes Gyuricza Luara Lucena Cassiano Luis Ernesto Farinha-Arcieri Ana Maria Alvim Liberatore

Fibrillin

Ectopia lentis

Ciliary processes

Microfibril

10.1016/j.exer.2021.108461

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Citations (6)

Sexual Dimorphism Determination by Piriform Aperture Morphometric Analysis in Brazilian Human Skulls

International Journal of Morphology (2009)

Mario Cantín Iván Suazo Galdames Daniela Alejandra Zavando Matamala Ricardo Luiz Smith

The sex determination of human skeletons is important in forensic and anthropological research.It can be carried out through qualitative or quantitative analysis of morphological parameters of dimorphism.The shape of the piriform aperture is one of the classic indicators of sexual dimorphism since it describes differences between males and females according to strong populationspecific behavior.The purpose of this study was to analyze the presence of sexual dimorphism in the size of the piriform aperture and its relationship with individual skin color.We used 90 human skulls from the Collection of the Federal Universidad de Sao Paulo (UNIFESP), with registered data on sex, age and skin color (classified as white, black and brown).The dimensions studied were: height, upper width and lower width of piriform aperture.All dimensions were greater in males than females, however, only the piriform aperture height was found to be significant with p <0.01.By analyzing differences and grouping them according skin color, the piriform aperture height was found to be significantly higher (p <0.05) in white, black and brown males.In the group of black individuals skulls, we found significant differences in the upper width (p <0.05).The main differences, related to the piriform aperture height and the low influence of skin color in the presence of sexual dimorphism in the piriform aperture size, are in contrast with what has been reported in the literature and justify the revision of the classic indicators used for diagnosis of sex in specific populations.

Sexual dimorphism

10.4067/s0717-95022009000200007

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Oto-Rhino-Laryngologia Nova (2001)

Roberto Stramare Stefano Puggina Filippo Marino H. de Maddalena Michael J. McKenna

10.1159/000069402

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Internal Auditory Canal: Pre- and Postnatal Growth

The Journal of Otolaryngology (2004)

Laís Vieira Bonaldi Aline do Lago Luciana Campanatti Crema Yotaka Fukuda Ricardo Luiz Smith

The purpose of this study was to describe the size and shape of the internal auditory canal (IAC) during development.The study was conducted in 98 dried temporal bones from 7-month-old fetuses to adults. Silicone mould casts of the IAC were used.The length of the IAC was measured on the moulds corresponding four walls as the diameter on the fundus, middle portion, and porus.Although size and shape vary considerably among individuals, the data showed no significant differences between the right and left sides of the same individual. The values of the wall length and porus diameter increase as a function of age, especially for the upper wall and horizontal diameter. Both middle portion diameters suffer variations at different ages, increasing and decreasing until reaching the final shape. The diameter of the fundus, near the inner ear, remains stable.Our results showed that during development, the shape of the IAC adapts to cranial growth, with those of adults and fetuses having a similar shape but different dimensions, which was quite evident near the porus.

Fundus (uterus)

10.2310/7070.2004.02006

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Corneal endothelial cell morphology of normal dogs in different ages

Veterinary Ophthalmology (2006)

G. N. Rodrigues José Luiz Laus Jaime Maia dos Santos Moacyr Pezati Rigueiro Ricardo Luiz Smith

Abstract Endothelial cell function is essential to maintain corneal transparency, but unfortunately the regenerative capacity of the endothelium is limited. There are only a few reports describing the effect of age on morphologic appearance of corneal endothelial cells of dogs. Studies of normal corneal endothelial cells in humans and dogs have shown a decrease in endothelial cell density (ECD) and an increase in pleomorphism and polymegethism with advancing age. The purpose of this study was to investigate the effect of age on ECD and endothelial cell morphology in dogs. A total of 30 dogs were divided into three groups (10 dogs/group) based on age: group 1 (2–12 months old), group 2 (24–72 months old), and group 3 (84 months or older). Corneas were processed for light and scanning electron microscopy. Results showed only difference in cell density between group 1 and groups 2 and 3, showing an initial decrease in cell density as the animal matured. Whereas there was significantly greater variation in cell size within the dogs in group 3 than there was within the other two groups, suggesting that there was increased polymegethism and pleomorphism with advancing age.

Pleomorphism (cytology)

Corneal Endothelium

10.1111/j.1463-5224.2006.00427.x

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Mensuracao do angulo de torcao tibial numa populacao adulta jovem por meio de um novo dispositivo

Revista Brasileira de Ortopedia (English Edition) (2004)

Sergio Jose Lawand Amâncio Ramalho Júnior Ricardo Luiz Smith

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Developmental Study of the Round Window Region

Cells Tissues Organs (1997)

Laís Vieira Bonaldi Marco Antonio De Angelis Ricardo Luiz Smith

A silicone impression method to study the anatomy of the round window region was used in 102 temporal bones belonging to individuals aged from 4 months of fetal life to 3-year-old children as well as adults. A total of 2,142 measurements of the round window, oval window and round window fossula was made in the molds. The data demonstrate that the round window shows a diameter from 1.21 mm (average for the short axis) to 1.74 mm (average for the long axis) and the circular shape was present in 55% of the adult temporal bones and in 18.18% of the fetal and infantile ones. The adult dimensions of the measured structures are reached during fetal development.

Round window

10.1159/000147961

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Citations (17)

Biometry of Hard Palate on Digital Photographs: A Methodology for Quantitative Measurements

International Journal of Morphology (2006)

Rafael Saviolo Moreira Emerson Alexandre Sgrott Fernando Seiji Ricardo Luiz Smith

The objective of this paper is to establish, validate and test the reproducibility and accuracy of a digital method to measure linear and angular distances in human hard palate of dry skulls.Digital photographs were made in 10 human adult skulls and measurements were made with the aid of AutoCAD software and with a digital caliper in the same skulls by one observer in a blind fashion to compare both methods.To validate the digital method, measurements was made in 20 skulls by 3 observers.The differences of the measurements were not statistically significant between both method and between the 3 observers.The use of digital cameras followed by image analysis with AutoCAD, a software initially developed for engineering and architecture, revealed to be an excellent tool for biometry in morphology in medical and dentistry areas combining easy handling with accessibility.

Hard palate

10.4067/s0717-95022006000100004

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Citations (8)

Gap Junctions between Mast Cells and Fibroblasts in the Developing Avian Eye

Cells Tissues Organs (1995)

Sônia Maria Oliani Ana Paula Girol Ricardo Luiz Smith

Mast cells are present in the eye of chick embryos from the 14th day onward, displaying metachromatic granules, mainly in the iris anterior surface and pectinate ligament. Ultrastructurally these cells show electron-dense granules and a few thin and short cytoplasmic projections in close contact with fibroblasts. Sometimes these contacts are extensive, with long fibroblast projections partially involving the mast cells. Gap junctions between mast cells and fibroblasts are observed only in the eyes of 16- and 20-day-old embryos. These intercellular specializations are represented by a close apposition of cytoplasmic membranes with an extension up to 300 nm. Gap junctions between mast cells and fibroblasts were not observed previously in vivo or in vitro, although in vitro studies have shown that a number of functionally critical interactions may occur between these cells. Our morphological findings suggest that, in vivo, fibroblasts interact with mast cells and may influence their maturation.

Apposition

10.1159/000147778

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Citations (24)

Tomographic analysis of the interalveolar space and thickness of the vestibular cortical bone in the parasymphyseal region of adult human mandibles

Surgical and Radiologic Anatomy (2010)

Atson Carlos de Souza Fernandes Sandra de Quadros Uzeda-Gonzalez Ricardo Luiz Smith Luís Garcia Alonso Fabio Mota Gonzalez

Mental foramen

Mandible (arthropod mouthpart)

Cadaveric spasm

Foramen

10.1007/s00276-010-0659-8

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Citations (5)

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