Siyu Wu

Shanghai Jiao Tong University

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Yugang Sun

Temple University

Ruixue Qi

Minzu University of China

Xiaobing Zuo

Argonne National Laboratory

Dandan Jiang

Dalian Maritime University

Jinghai Liu

National University of Mongolia

Qilin Wei

Shandong University

Chengde Mao

Purdue University West Lafayette

Yangyang Li

Materials Science & Engineering

Wen Jiang

Purdue University West Lafayette

Lidong Wang

North China Electric Power University

Cooperative Institutions

Chinese Academy of Sciences

Wuhan University of Technology

Jilin University

Shanghai Jiao Tong University

Sichuan University

Zhejiang University

University of Chinese Academy of Sciences

Guangxi Medical University

Chinese Academy of Medical Sciences & Peking Union Medical College

University of Science and Technology of China

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In vivo production of RNA nanostructures via programmed folding of single-stranded RNAs

Nature Communications (2018)

Mo Li Mengxi Zheng Siyu Wu Cheng Tian Di Liu

Programmed self-assembly of nucleic acids is a powerful approach for nano-constructions. The assembled nanostructures have been explored for various applications. However, nucleic acid assembly often requires chemical or in vitro enzymatical synthesis of DNA or RNA, which is not a cost-effective production method on a large scale. In addition, the difficulty of cellular delivery limits the in vivo applications. Herein we report a strategy that mimics protein production. Gene-encoded DNA duplexes are transcribed into single-stranded RNAs, which self-fold into well-defined RNA nanostructures in the same way as polypeptide chains fold into proteins. The resulting nanostructure contains only one component RNA molecule. This approach allows both in vitro and in vivo production of RNA nanostructures. In vivo synthesized RNA strands can fold into designed nanostructures inside cells. This work not only suggests a way to synthesize RNA nanostructures on a large scale and at a low cost but also facilitates the in vivo applications.

Nucleic acid structure

10.1038/s41467-018-04652-4

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Citations (101)

Colorimetric detection of bisphenol A in food and water based on the laccase-mimicking activity of silver phosphate nanoparticles

Food Innovation and Advances (2025)

Siyu Wu Jiali Chen Yue Tang Yuangen Wu

10.48130/fia-0025-0008

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Citations (0)

Retrosynthetic Analysis-Guided Breaking Tile Symmetry for the Assembly of Complex DNA Nanostructures

Journal of the American Chemical Society (2016)

Pengfei Wang Siyu Wu Cheng Tian Guimei Yu Wen Jiang

Current tile-based DNA self-assembly produces simple repetitive or highly symmetric structures. In the case of 2D lattices, the unit cell often contains only one basic tile because the tiles often are symmetric (in terms of either the backbone or the sequence). In this work, we have applied retrosynthetic analysis to determine the minimal asymmetric units for complex DNA nanostructures. Such analysis guides us to break the intrinsic structural symmetries of the tiles to achieve high structural complexities. This strategy has led to the construction of several DNA nanostructures that are not accessible from conventional symmetric tile designs. Along with previous studies, herein we have established a set of four fundamental rules regarding tile-based assembly. Such rules could serve as guidelines for the design of DNA nanostructures.

Sequence (biology)

10.1021/jacs.6b06074

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Citations (51)

Deciphering the Optical Absorption Spectra of Ultrafine Metal Nanoparticles Dispersed on Submicron Silica Spheres

The Journal of Physical Chemistry C (2022)

Qilin Wei Matas Simukaitis Siyu Wu Jonathan J. Foley Yugang Sun

Optical absorption of metal nanoparticles on dielectric supports that do not absorb light becomes complicated due to the convolution of light scattering of the dielectric supports. Identifying the origin of optical absorption characteristics in metal/dielectric composite materials is vital to designing materials with desirable optical absorption properties for interesting applications such as photocatalysis. In this work, we systematically investigated the optical absorption of ultrafine metal nanoparticles (ufMNPs) supported on silica spheres (SiOx-SPs) using absorption-sensitive diffuse reflectance spectroscopy (DRS) and theoretical modeling/calculations. The comparisons between experimental measurements and theoretical predictions reveal that the SiOx-SPs in ufMNPs/SiOx-SP composite powders exhibit three types of scattering to determine the optical absorption of the supported ufMNPs. First, localized light-scattering resonances near the surface of individual SiOx-SPs with large sizes generate enhanced electric fields to promote strong optical absorption in the ufMNPs with well-defined peaks. Second, nonunidirectional diffuse light scattered from individual SiOx-SPs with relatively small sizes penetrates the composite powders to be absorbed by the ufMNPs, exhibiting uphill and peakless absorption profiles. Third, the diffuse light can be modulated by the ordered packing of the composite particles that exhibit photonic reflection at the stop band, resulting in a valley in the DRS spectrum of a composite powder. The deconvolution of optical absorption in the ufMNPs/SiOx-SP composite particles opens an avenue to rationally design composite materials with favorable light absorption properties, for example, nonlinearity of localized absorption versus linearity of diffuse absorption.

Diffuse reflection

10.1021/acs.jpcc.2c04303

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Citations (3)

Pt–Cu hierarchical quasi great dodecahedrons with abundant twinning defects for hydrogen evolution

Chemical Communications (2017)

Ruijie Huang Zhongti Sun Sheng Chen Siyu Wu Zeqi Shen

Hierarchical metal nanostructures which exhibit an open structure and a high density of twin defects accessible to reactants hold great promise in catalysis.

10.1039/c7cc03643d

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Citations (22)

Enabling selective aerobic oxidation of alcohols to aldehydes by hot electrons in quantum-sized Rh nanocubes

Materials Today Energy (2018)

Xinyan Dai Kowsalya Devi Rasamani Siyu Wu Yugang Sun

Oxidizing agent

Alcohol Oxidation

10.1016/j.mtener.2018.08.003

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Citations (14)

Preservation effects of chitosan/polyvinyl alcohol/clove essential oil antifungal film on yellow peaches: Physicochemical properties and fruit quality assessment

Food Control (2024)

Liyuan Wang Hongjun Fu Qian Tan Siyu Wu Yan Wang

Polyvinyl Alcohol

Titratable acid

Thermogravimetric analysis

10.1016/j.foodcont.2024.110582

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Citations (8)

Quantum‐Sized Metal Catalysts for Hot‐Electron‐Driven Chemical Transformation

Advanced Materials (2018)

Qilin Wei Siyu Wu Yugang Sun

Abstract Hot‐electron‐driven chemical transformation (HEDCT) represents an emerging research area in utilizing photoresponsive nanoparticles to enable efficient solar‐to‐chemical conversion. The unique properties of quantum‐sized metal nanoparticles (QSMNPs) make them a class of photocatalysts that can generate hot electrons to drive surface chemical reactions with high quantum efficiency. Compared to the conventional thermal‐driven chemical reactions, HEDCT offers the advantages of accelerating reaction rate, improving reaction selectivity, and possibly enabling the occurrence of thermodynamically endergonic reactions. Despite its embryonic stage of development, using QSMNPs for HEDCT shows great promise. Herein, a timely overview on the research progress is provided with a focus on the fundamental quantum processes involved in the photoexcitation of hot electrons and the following HEDCT on the surface of QSMNPs. The last section discusses the challenges, which also represent the opportunities for the materials research community, in designing robust QSMNP photocatalysts and understanding the fundamental quantum phenomena in HEDCT.

Photoexcitation

Hot electron

Quantum chemical

Nanomaterials

Chemical transformation

10.1002/adma.201802082

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Citations (68)

A green and robust solid catalyst facilitating the magnesium sulfite oxidation in the magnesia desulfurization process

Journal of Materials Chemistry A (2017)

Lidong Wang Tieyue Qi Siyu Wu Shihan Zhang Dan Qi

Effect of cobalt loading on the dispersity and catalysis performance.

Dispersity

10.1039/c7ta01513e

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Citations (36)

Self-efficacy and healthy lifestyle behaviors as mediators between COVID-19 care knowledge and health status

Scientific Reports (2024)

Mingzhu Zhao Y. Xin Weiguang Ni Qian Liu Yiwen Ding

The COVID-19 epidemic has affected the psychological well-being and daily life of college students, leading to a decrease in their quality of life. Health status can be influenced by a variety of factors. This study aims to assess the current health status of university students and explore the relationships among COVID-19 care knowledge, self-efficacy, healthy lifestyle behaviors, and health status and how these factors are influenced. Among the 1694 participants, 49.4% were male, 50.6% were female, and 82.2% were freshmen. The results revealed that health status across all dimensions decreased to some extent. COVID-19 care knowledge affected both physical and mental component summaries. The results suggest that improving COVID-19 care knowledge, strengthening self-efficacy, and promoting the development of healthy lifestyle behaviors can positively impact their health status. Here, we explore the health status of college students with COVID-19 infection and the factors and mechanisms that influence it to guide health interventions to better meet the challenges posed by future outbreaks.

Self-Efficacy

10.1038/s41598-024-82099-y

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Citations (0)