Lingxin Zheng

Xiamen University

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Xiaojia Huang

Xiamen University

Jiangyi Wu

Chinese Academy of Medical Sciences & Peking Union Medical College

Ju Li

Xuzhou Medical College

Jingjuan Wang

Xiamen University

Xiaochen Liu

Liaoning University

Xinyi Zheng

Hainan University

Chenying Su

Wenzhou Medical University

Yuanfei Wu

Xiamen University

Jinling Wei

City University of Macau

Youfang Huang

Fujian Agriculture and Forestry University

Cooperative Institutions

Zhejiang Chinese Medical University

Xiamen University

State Key Laboratory of Marine Environmental Science

Zhejiang University

Northeast Normal University

Collaborative Innovation Center of Chemistry for Energy Materials

Nanjing University of Science and Technology

China Agricultural University

Chinese Academy of Agricultural Sciences

Jiangsu Province Hospital

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One-pot fabrication of poly (ionic liquid)s functionalized magnetic adsorbent for efficient enrichment of phenylurea herbicides in environmental waters

Analytica Chimica Acta (2022)

Kaisheng Hong Youfang Huang Lingxin Zheng Xinyi Zheng Xiaojia Huang

Azobisisobutyronitrile

Ethylene glycol dimethacrylate

Solid phase extraction

Linear range

10.1016/j.aca.2022.339549

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Citations (19)

Preparation of microelectrode based on molecularly imprinted monolith using ionic liquids as functional monomers for specific separation and enrichment of phenolic acids

Separation and Purification Technology (2024)

Lingxin Zheng Jiangyi Wu Jingjuan Wang Yuanfei Wu Xiaojia Huang

Monolith

Molecularly imprinted polymer

10.1016/j.seppur.2024.128548

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Citations (2)

Fabrication of Molecularly Imprinted Polymer-Based Electrode as the Adsorbent of Electric Field Assisted Solid-Phase Microextraction for Specific Extraction and Quantification of Phytohormones

Jiangyi Wu Lingxin Zheng Xiaojia Huang

Specific extraction and separation plays a pivotal role in the accurate quantification of trace phytohormones (PHs) which can engender potential danger to eco-environment and human health. However, specific capture of PHs is challenging because of its high polarity. Some sample preparation techniques have been employed to extract PHs, but there are still various limitations should be circumvented. In this study, under the assistance of electric field, a new molecularly imprinted polymer-based electrode (MIP@ED) was in-situ prepared using 3-indoleacetic acid (IAA) as template and employed as the adsorbent of electric field assisted solid-phase microextraction (EA-SPME) for specific capture of PHs. Results revealed that the implementation of electric field during the preparation of MIP@ED and EA-SPME procedures apparently improved the extraction selectivity, the selective factors towards IAA and its structural analogues increased from 2.09-2.45 to 2.88-3.51. Under the beneficial conditions, the proposed MIP@ED/EA-SPME was combined with HPLC technique to monitor trace PHs in various waters and agricultural products. The achieved limits of detection were in the ranges of 0.0053-0.011 μg/L and 0.048-0.12 μg/kg for water and agricultural product, respectively. The established approach was successfully applied to quantify trace PHs in real samples, and the spiked recoveries varied from 84.0% to 118% with good repeatability (RSDs blow 10%). The obtained results well evidenced that the developed approach employing the MIP@ED/EA-SPME technique presented high sensitivity, good selectivity, satisfactory reproducibility and environmental friendliness in the monitoring of trace PHs in complex samples. In addition, the current study supplied a new strategy for improving the specific recognition performance of MIP-based SPME.

Molecularly imprinted polymer

Solid-Phase Microextraction

Solid phase extraction

Molecular imprinting

10.2139/ssrn.4580967

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The Construction of the Off-campus Field of Five Education Integration

Lecture Notes in Education Psychology and Public Media (2023)

Lingxin Zheng

Five education integration and learning field construction are two important parts of education in the new era that need to be paid attention to. This project intends to carry out research on the innovative design of the construction of the five-education integrated learning field through a large number of literature queries, interviews, and investigations to analyze the requirements of Five Education Integration, choose a suitable learning field, study the construction of home-school cooperation in Taiwan and the cooperation between Japanese schools and private schools, combine the psychological characteristics of students cognitive development and social status, and design a home-school that utilizes advanced. This paper determines the main content and direction of the research design: using the advanced family committee-style home-school cooperation model, taking the idle off-campus institutions and social places after the double reduction as the basis, and the psychological understanding of education integration as the basis for curriculum design.

Idle

Social Integration

10.54254/2753-7048/2/2022634

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Electric Field-Assisted Synthesis of Molecularly Imprinted Microelectrode for Specific Extraction of Triazoles Before Quantification with Hplc

Lingxin Zheng Lei Wang Xiaojia Huang

Molecularly imprinted polymer

10.2139/ssrn.5041549

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Assessment of bidirectional relationships between systemic lupus erythematosus and anxiety disorder: A two-sample Mendelian randomization study

Lupus (2023)

Qin Zhang Lingxin Zheng Kepeng Yang

Observational studies have demonstrated that there was a significant correlation between systemic lupus erythematosus (SLE) and anxiety disorder, but the causal relationship between them is not so clearly established. This study aims to reveal the potential causal link between SLE and anxiety disorder.Summary statistical data of SLE and anxiety disorder were from two large-scale genome-wide association studies (GWAS) of European ancestry, followed by a bidirectional two-sample Mendelian randomization (MR) analysis. The inverse variance-weighted (IVW) method was used as the main method to evaluate causal effects, while MR-Egger, weighted median, simple mode, and weighted mode were supplementary methods. Outliers were excluded by MR-pleiotropy residual sum and outlier (MR-PRESSO). Cochran's Q test, MR-Egger intercept test, and leave-one-out analysis were used to evaluate the stability of the results.According to the results of IVW, we did not observe that there was a statistically significant causal association between genetically predicted SLE and the risk of anxiety disorder (OR = 1.000, 95%CI = 0.992 to 1.008, p =.997). Conversely, there were no causal effects between anxiety disorder and SLE risk (OR = 1.000, 95%CI = 0.992 to 1.008, p = .997). A similar result was obtained by supplementing the MR method. In addition, sensitivity analysis indicated high stability of the result.Bidirectional two-sample MR study does not support the causal relationship between SLE and anxiety disorder.

Mendelian Randomization

10.1177/09612033231154784

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Citations (1)

Hemophilia A developing cerebral infarction after surgical treatment of giant hemophilic pseudotumor: a case report

BMC Surgery (2022)

Yi-Qing Ling Zhenyu Shi Chenying Su Xiaochen Liu Lingxin Zheng

Abstract Background Cerebral infarction (CI) is an unusual complication in patients with bleeding disorders. To our knowledge, this is the first case of postoperative internal border-zone infarction (I-BZI) from Hemophilia A. Case presentation We present a case of Hemophilia A developing I-BZI, after surgical treatment of giant hemophilic pseudotumor. A 36-year-old man was introduced from other hospital by Hemophilia with giant hemophilic pseudotumor in his left thigh. Patient and his relatives did not have a history of thrombophilia. After excluding the relevant surgical contraindications, we performed the operation of pseudotumor resection. Prior to surgery, blood tests revealed hemoglobin of 137 g/L. FVIII activity was 1.5%. Activated partial thromboplastin time (APTT) was 71.50 s and D-dimer was 3.33 mg/L FEU. Immediately before surgery, the patient received an intravenous infusion of FVIII products (Xyntha ® ) at a dose of 3500 IU for his body weight of 80 kg. Post-operative day two (POD2), patient developed vomiting, decreased response, and dysarthria. Hemoglobin was 54 g/L with blood pressure of 110/70 mmHg. Magnetic resonance imaging of the brain showed there were multiple acute cerebral infarctions in bilateral lateral ventricles (internal border zone) and multiple ischemic foci in the white matter areas and basal ganglia of the bilateral cerebral hemispheres. This case suggested that acute severe anemia can be one of the causes of I-BZI. Conclusions For the treatment of I-BZI caused by acute anemia from Hemophilia A, volume expansion, red blood cell supplement and continuous improvement of coagulation with suitable dose of factor VIII (FVIII) should be considered to improve prognosis.

Midline shift

10.1186/s12893-022-01753-2

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Fabrication and evaluation of a molecular-imprinted-polymer functionalized electrode for selective electric field-assisted solid-phase microextraction of phytohormones

Talanta (2023)

Jiangyi Wu Lingxin Zheng Xiaojia Huang

Solid-Phase Microextraction

Molecularly imprinted polymer

Repeatability

10.1016/j.talanta.2023.125572

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Citations (5)