Simonetta Blengino

IRCCS Istituto Auxologico Italiano

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Antonio Colombo

EMO GVM Centro Cuore Columbus

Giovanni Martini

EMO GVM Centro Cuore Columbus

Carlo Di Mario

Azienda Ospedaliero-Universitaria Careggi

Luigi Maiello

University of Padua

Léo Finci

University Hospital of Geneva

Massimo Ferraro

EMO GVM Centro Cuore Columbus

Patrick Hall

Queen Elizabeth Hospital Birmingham

Gianfranco Parati

IRCCS Istituto Auxologico Italiano

Akira Itoh

Toshiba (Japan)

Lucia Di Francesco

University of Teramo

Cooperative Institutions

Istituti di Ricovero e Cura a Carattere Scientifico

University of Milan

IRCCS Istituto Auxologico Italiano

University of Milano-Bicocca

Ospedale Maggiore

University of Padua

University of Brescia

EMO GVM Centro Cuore Columbus

Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda

Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

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Angiographic and clinical outcome following coronary stenting of small vessels

Journal of the American College of Cardiology (1998)

Tatsuro Akiyama Issam Moussa Bernhard Reimers Massimo Ferraro Yoshio Kobayashi

Lumen (anatomy)

10.1016/s0735-1097(98)00444-6

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Citations (285)

A brief period of intensive cardiac rehabilitation improves global longitudinal strain and diastolic function after a first uncomplicated myocardial infarction

Acta Cardiologica (2017)

Gabriella Malfatto Miriam Revera Giovanna Branzi Francesca Ciambellotti Alessia Giglio

Objectives In patients with abnormal left ventricular ejection fraction (LVEF) after acute myocardial infarction (AMI), cardiac rehabilitation with physical training prevents cardiac remodelling. To define the role of rehabilitation in the recovery of ventricular function in less severe cases, we studied its effects on more refined indexes of left ventricular function in uncomplicated, low-risk patients. Methods and results Fifty-five patients underwent percutaneous coronary revascularization after uncomplicated first AMI. Thirty-four started cardiac rehabilitation with counselling and physical training; 21 patients did not train, followed a counselling program and were taken as controls. Echocardiography was performed at baseline, after rehabilitation or counselling program and at six months follow-up. We measured: global strain (GS%) with speckle tracking analysis, E/e' by tissue Doppler imaging (TDI), left ventricular elastance (KLV) from the deceleration time (DT), LVEF, systolic and diastolic volumes, wall motion score index (WMSI). At baseline, groups had similar GS%, KLV, LVEF, DT, E/e', systolic and diastolic volumes, WMSI. Rehabilitation increased peak VO2 by 18% (P < 0.05) and improved GS%, KLV, LVEF, E/e' and WMSI (P < 0.02) that were unchanged in controls. The improvement persisted at six months. Conclusions After a first uncomplicated AMI, abnormalities of left systolic and diastolic ventricular function may be present persisting over time despite a normal LVEF, which are fully reverted by cardiac rehabilitation.

10.1080/00015385.2017.1305196

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Citations (14)

Pericardial effusion requiring pericardiocentesis in a girl with anorexia nervosa

International Journal of Eating Disorders (2006)

Nicoletta Polli Simonetta Blengino Mirella Moro Daniela Zappulli Massimo Scacchi

Objective: Silent pericardial effusion is frequently observed in patients with anorexia nervosa. The nature of the pericardial fluid could never be established, as pericardiocentesis was ethically unfeasible. Method: We describe the case of a girl with anorexia nervosa in whom an initial, clinically irrelevant pericardial effusion increased rapidly, making pericardiocentesis necessary to prevent cardiac tamponade. Results: It was thus possible to exclude the inflammatory or infectious nature of the pericardial fluid, although the pathogenesis of this cardiac alteration remains obscure. Conclusion: Echocardiographic examination appears to be strongly advisable in patients with anorexia nervosa. © 2006 by Wiley Periodicals, Inc. Int J Eat Disord 2006

Pericardiocentesis

Anorexia nervosa

Girl

Pericardial fluid

Anorexia

10.1002/eat.20307

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Citations (22)

967–16 Preliminary Experience of Coronary Stenting with the Micro Stent™

Journal of the American College of Cardiology (1995)

Antonio Colombo Luigi Maiello Shigeru Nakamura Patrick Hall Simonetta Blengino

Intravascular Ultrasound

10.1016/0735-1097(95)92450-j

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Citations (4)

980-38 A Randomized Study of the 8 French Hemostatic Puncture Closure Device vs Manual Compression After Coronary Interventions

Journal of the American College of Cardiology (1995)

Simonetta Blengino Brenda Hann Luigi Maiello Shigeru Nakamura Patrick Hall

Vascular closure device

10.1016/0735-1097(95)92548-j

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Citations (5)

Coronary stent implantation in aorto-ostial lesions: Immediate and follow-up results

Journal of the American College of Cardiology (1996)

Antonio Colombo Akira Itoh Luigi Maiello Simonetta Blengino Carlo Di Mario

Coronary stent

10.1016/s0735-1097(96)81895-x

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Citations (3)

Indobufen versus aspirin plus dipyridamole after coronary artery bypass surgery

Coronary Artery Disease (1991)

F Rovelli L Campolo G Cataldo A Pellegrini P.M. Mannucci

Dipyridamole

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Citations (18)

[Safety and efficacy of early discharge and outpatient rehabilitation after myocardial infarction for low-risk patients].

PubMed (2019)

V Sánchez-Matamoros Piazza Simonetta Blengino Carlotta Munforti Mauro Musmeci Alessia Giglio

Guidelines recommend early discharge and rehabilitation after ST-elevation myocardial infarction (STEMI) in low-risk patients. However, low risk is not established according to well-defined criteria and often it depends on subjective judgment. The aim of this real-life study is to confirm that early discharge is safe in patients at low risk according to selected criteria and subsequent outpatient rehabilitation is associated with clinical benefits.Patients with STEMI treated with primary percutaneous coronary intervention from October 2010 to October 2017, identified as being at low risk (according to predefined criteria), discharged by day 5, were studied retrospectively. Basal characteristics and 30-day outcome were evaluated and a comparison was made between patients who completed or did not complete outpatient rehabilitation.We enrolled 193 STEMI patients treated with percutaneous coronary intervention for STEMI, early discharged and at low risk: 132 completed outpatient rehabilitation and 61 did not. The increase in cardiac enzymes and the occurrence of arrhythmias were the only independent predictors of completion of outpatient rehabilitation. After 30 days from discharge, adverse events were rare and not significantly different between groups. Optimal pharmacological therapy was achieved more often in the rehabilitation group (58.3% vs 44.3%; p<0.05).Early discharge within 5 days of STEMI has been proved feasible and safe in our population of well-defined low-risk patients. Early participation in a rehabilitation program was associated with a more adequate titration of therapy.

Outpatient clinic

10.1714/3254.32227

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Citations (0)

A Randomized Comparison of Combined Ticlopidine and Aspirin Therapy Versus Aspirin Therapy Alone After Successful Intravascular Ultrasound–Guided Stent Implantation

Circulation (1996)

Patrick Hall Shigeru Nakamura Luigi Maiello Akira Itoh Simonetta Blengino

Background Previous studies have shown that it is feasible to withhold anticoagulation after a successful intracoronary stent procedure with a low incidence of stent thrombosis. The importance of specific antiplatelet agents when stenting is performed without anticoagulation is unknown. Methods and Results After successful intravascular ultrasound–guided stenting, 226 patients were randomly assigned to receive either aspirin therapy alone (n=103) or a combination of ticlopidine and short-term aspirin therapy (n=123). Primary angiographic and clinical end points were stent thrombosis, death, myocardial infarction, the need for postprocedure coronary artery bypass surgery or repeated angioplasty, and significant medication side effects requiring termination of the medication within the first month of a successful procedure. At 1 month, the rate of stent thrombosis was 2.9% in the aspirin only group and 0.8% in the ticlopidine-aspirin group ( P =.2). Cumulative major clinical events after successful stenting occurred in 3.9% of the patients in the aspirin group and in 0.8% in the ticlopidine-aspirin group ( P =.1). There were no medication side effects in the aspirin group; in the combined ticlopidine-aspirin group, medication side effects occurred in 3 patients ( P =.2). Conclusions At 1 month, there was no difference in the incidence of stent thrombosis or other clinical end points between the two poststent antiplatelet regimens. However, the relatively small size of the study and the low incidence of thrombosis events may have contributed to the failure to detect differences in angiographic and clinical end points between the two groups.

Ticlopidine

Intravascular Ultrasound

Coronary stent

10.1161/01.cir.93.2.215

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Citations (287)

Stents DonÕt Require Systemic Anticoagulation.But the Technique (and Results) Must be Optimal.

PubMed (1996)

I. Moussa Carlo Di Mario Di Francesco L Bernhard Reimers Simonetta Blengino

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