A new method of endometrial ablation has been presented. This is the method of bipolar tridimensional device "NOVA SURE". This innovative method enables to destruct the basal and functional layer of the uterus and thus leads to amenorrhea and hypomenorrhea.
Synovial sarcoma is an aggressive soft tissue sarcoma, which most often occurs in the limbs near the joints. It accounts for 5-10% of all soft tissue sarcomas. It extremely rarely affects the pelvis. So far, only 4 cases of primary involvement of the adnexa have been described. We present a case of a 77-year-old female patient diagnosed with a rapidly growing pelvic formation, subsequently diagnosed as monophasic synovial sarcoma of the ovary. Synovial sarcoma derived from the adnexa is a rare disease that is virtually unknown. The diagnosis is complex, and there is a poor prognosis.
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Yordanov A, Kostov S, Kornovski Y, et al. Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding. Menopause Review/Przegląd Menopauzalny. 2022;21(4):285-288. doi:10.5114/pm.2022.124020. APA Yordanov, A., Kostov, S., Kornovski, Y., Ivanova, Y., Slavchev, S., & Kostov, G. et al. (2022). Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding. Menopause Review/Przegląd Menopauzalny, 21(4), 285-288. https://doi.org/10.5114/pm.2022.124020 Chicago Yordanov, Angel, Stoyan Kostov, Yavor Kornovski, Yonka Ivanova, Stanislav Slavchev, Gancho Kostov, and Strahil Strashilov. 2022. "Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding". Menopause Review/Przegląd Menopauzalny 21 (4): 285-288. doi:10.5114/pm.2022.124020. Harvard Yordanov, A., Kostov, S., Kornovski, Y., Ivanova, Y., Slavchev, S., Kostov, G., and Strashilov, S. (2022). Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding. Menopause Review/Przegląd Menopauzalny, 21(4), pp.285-288. https://doi.org/10.5114/pm.2022.124020 MLA Yordanov, Angel et al. "Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding." Menopause Review/Przegląd Menopauzalny, vol. 21, no. 4, 2022, pp. 285-288. doi:10.5114/pm.2022.124020. Vancouver Yordanov A, Kostov S, Kornovski Y, Ivanova Y, Slavchev S, Kostov G et al. Initial presentation of renal cell carcinoma as a vaginal mass with excessive bleeding. Menopause Review/Przegląd Menopauzalny. 2022;21(4):285-288. doi:10.5114/pm.2022.124020.
To determine the incidence of the histopathological findings indicative for risk of recurrence in patients with locally advanced cervical cancer (LACC) who were treated with neoadjuvant chemotherapy (NCT) and radiation therapy (RT) before operation.Sixty-three patients were included: 45 patients (group 1) underwent external beam RT and then surgical treatment followed by postoperative RT, and 18 (group 2) patients were treated with NCT and surgery followed by postoperative RT. Surgery was class III-V radical hysterectomy with pelvic lymph node dissection (LND), and paraaortic LND at indication. NCT included 2-3 courses of cisplatin, ifosfamide and bleomycin administered at 3-week intervals. In group 1 FIGO stage IIB prevailed (n=29, 64.4%). Forty-four (97.8%) patients had squamous cell carcinoma and 1 (5.6%) adenosquamous carcinoma. In group 2 stage IIB also prevailed (n=13, 72.2%), whereas all 18 (100%) patients had squamous cell carcinoma. The average age in group 1 and 2 was 48.8 years (range 31-69) and 46.3 years (range 32-64), respectively.In group 1 lymph node metastases (LNM) were found in 35.56% of the cases, macroscopically detectable LNM in 15.6%, LNM above the common iliac artery level in 11.1%, multiple LNM (>3 LNM) in 17.8%, parametrial invasion in 4.4%, deep stromal invasion in 31.1%, lymphovascular space invasion (LVSI) in 13.3%, infiltration of canalis cervicalis in 15.6%, infiltration of isthmus uteri in 8.9% and ovarian metastases in 4.4%. In group 2 LNM were found in 38.89% of the patients, macroscopically detectable metastases in 22%, multiple (>3 LNM) LNM in 17%, LNM above the common iliac artery level in 22%, deep stromal invasion in 47%, parametrial infiltration in 24%, LVSI in 12%, tumor infiltration in canalis cervicalis in 12%, and ovarian metastases in 6%.NCT followed by surgical treatment and RT leads to postoperative histological results that are not worse than the standard preoperative RT approach.
The germ-cells tumors are the most common ovarian malignancy in young women between 15-25 years. Often advanced disease is present at the time of diagnosis. The management and treatment approaches of disgerminoma and immature teratoma, as most common germ-cells tumors (GST), are presented. Two clinical cases of advanced stages of GST with complete remision after conservative surgical treatment and chemotherapy have been reviewed.
Review was made of the literature about the long time used techniques Vaginal radical trachelectomy (VRT) and abdominal radical trachelectomy (ART) in respect of the following items--oncological results, obstetric outcomes, complications.
The authors describe a rare case of bilateral tubal pregnancy after IVF. The patient is with secondary infertility. The preceding diagnostic laparoscopy excluded the presence of tubal factor. The results of the spermogram show average to severe form of Oligoasthenozoospermia. Short protocol with GnRH-antagonist was performed and two embryos were transferred on the third day. On the 36th day after the embryo transfer the patient was hospitalized with abdominal pain in the right hypogastric region, clinical and ultrasound indications for hemoperitoneum. Urgent laparotomy was performed followed by salpingectomy dextra due to hemoperitoneum caused by tubal abortion. The examination of the left adnexa reveals uruptured tubal pregnancy in the isthmic part of the tube and the decision for salpingectomy sinistra was taken. Histological examinations confirmed the diagnosis of ectopic pregnancy in both tubes. The frequency of some rare forms and localizations of ectopic as well as heterotopic pregnancies increase after ART.
Gestational trophoblastic disease (GTD) covers a range of proliferative disorders from non-neoplastic hydatid moles to malignant neoplastic conditions such as choriocarcinoma. The incidence of these diseases is low and often challenging to diagnose. Placental site trophoblastic tumour (PSTT) is the rarest form of GTD, accounting for up to 3% of all cases. We present a case of a 35-year-old patient diagnosed with PSTT mimicking an intramural pregnancy. Placental site trophoblastic tumour occurred after pregnancy, which ended as a blighted ovum. β-hCG was not very high, and the patient had no complaints. The diagnosis was made after resection of formation which was accepted for intramural pregnancy. To our knowledge, this is the first such case described in the literature. A hysterectomy performed later confirmed the absence of a residual tumour after conservative intervention. The lack of distant metastases, confirmed by positron emission tomography-computed tomography scan, allowed for only hysterectomy with bilateral salpingo-oophorectomy to be performed. The patient was classified as low risk according to the World Health Organization (WHO) scoring system. Placental site trophoblastic tumour is a rare malignant tumour (despite its WHO coding) from the group of GTDs. It is not presented with a classic clinical picture, and its clinical diagnosis is challenging. However, clinicians should consider it in the case of unclear events after any type of pregnancy.
