Paul D. Hamilton

Veterans Health Administration

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Nathan Ravi

Washington University in St. Louis

Usha P. Andley

Washington University in St. Louis

Hyder A. Aliyar

DuPont (United States)

Matthew A. Reilly

The Ohio State University

J. A. Fernandez‐Pol

Molecular Oncology (United States)

Katelyn E. Swindle‐Reilly

The Ohio State University

D J Klos

Molecular Oncology (United States)

Jessica J. Struckhoff

Veterans Health Administration

Hongwei Du

Zhejiang University

Brian Rapp

Washington University in St. Louis

Cooperative Institutions

Washington University in St. Louis

University of Washington

Cranfield University

University of Oxford

Veterans Health Administration

St. Louis VA Medical Center

Saint Louis University

University of California, San Francisco

Viewpoints Research Institute

Cornell University

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Evaluation of Poly (Sodium Methacrylate) Materials as Potential Vitreous and Lens Substitutes

Investigative Ophthalmology & Visual Science (2009)

Nathan Ravi Paul D. Hamilton Matthew A. Reilly

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Injectable in situ Physically and Chemically Crosslinkable Gellan Hydrogel

Macromolecular Bioscience (2012)

Hongwei Du Paul D. Hamilton Matthew A. Reilly Nathan Ravi

An injectable, in situ physically and chemically crosslinkable gellan hydrogel is synthesized via gellan thiolation. The thiolation does not alter the gellan's unique 3-D conformation, but leads to a lower phase transition temperature under physiological conditions and stable chemical crosslinking. The synthesis and hydrogels are characterized by (1)H NMR, FT-IR, CD, or rheology measurements. The injectability and the tissue culture cell viability is also tested. The thiolated gellan hydrogel exhibits merits, such as ease for injection, quick gelation, lower gelling temperature, stable structure, and nontoxicity, which make it promising in biomedicine and bioengineering as an injectable hydrogel.

Gellan gum

10.1002/mabi.201100422

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Citations (50)

The Cambridge Companion to Wordsworth

Cambridge University Press eBooks (2003)

Stephen Gill Stephen Joel Gill Nicola Trott Duncan Wu James A. Butler

The Cambridge Companion to Wordsworth provides a wide-ranging account of one of the most famous Romantic poets. Specially commissioned essays cover all the important aspects of this multi-faceted writer; the volume examines his poetic achievement with a chapter on poetic craft, while other chapters focus on the origin of his poetry and on the challenges it presented and continues to present. Further contributions include discussions of The Prelude and The Recluse, Wordsworth as philosophic poet, his writing in relation to European Romanticism, and Wordsworth as Nature poet. The collection, by an international team of established specialists concludes with a lucid account of the history of Wordsworth's texts, and offers students invaluable reference material including a chronology and guides to further reading.The volume aims to ensure that its readers will be grounded in the history of Wordsworth's career and his critical reception.

Title page

10.1017/ccol0521641160

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Citations (43)

Patient-Reported and Radiological Outcomes of Short Scarf Osteotomy Fixed with a Single Screw: A Prospective Study of 271 Osteotomies

The Foot (2024)

Frideriki Poutoglidou Iqraa Khan Andrea Sott Paul D. Hamilton Sun Young Jeong

Avascular Necrosis

10.1016/j.foot.2024.102130

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Analysis of a Blend of Poly(acryamide) Gels with Varying Sodium Acrylate Formulations for Use in Vitreous Hydrogel Substitutes

Investigative Ophthalmology & Visual Science (2013)

Paul D. Hamilton N. Padmanabha Iyer Nathan Ravi

Sodium polyacrylate

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Development of a Biomimetic Hydrogel Vitreous Substitute That Forms in situ

Investigative Ophthalmology & Visual Science (2008)

Katelyn E. Swindle‐Reilly Paul D. Hamilton Nathan Ravi

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Dynamic multi-arm radial lens stretcher: A robotic analog of the ciliary body

Experimental Eye Research (2007)

Matthew A. Reilly Paul D. Hamilton Nathan Ravi

Force transducer

10.1016/j.exer.2007.10.005

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Citations (18)

Tools and techniques - what we need or what people think we want?

Paul D. Hamilton Brian H. MacGillivray Robert Bradshaw J. E. Strutt Simon Pollard

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Changes in relative histone abundance and heterochromatin in αA-crystallin and αB-crystallin knock-in mutant mouse lenses

BMC Research Notes (2020)

Usha P. Andley Brittney N. Naumann Paul D. Hamilton Stephanie L Bozeman

Understanding the mechanisms of cataract formation is important for age-related and hereditary cataracts caused by mutations in lens protein genes. Lens proteins of the crystallin gene families α-, β-, and γ-crystallin are the most abundant proteins in the lens. Single point mutations in crystallin genes cause autosomal dominant cataracts in multigenerational families. Our previous proteomic and RNAseq studies identified genes and proteins altered in the early stages of cataract formation in mouse models. Histones H2A, H2B, and H4 increase in abundance in αA- and αB-crystallin mutant mouse lenses and in cultured cells expressing the mutant form of αA-crystallin linked with hereditary cataracts. In this study of histones in mutant lenses, we extracted histones from adult mouse lenses from cryaa-R49C and cryab-R120G mutant knock-in mice. We characterized the histones using matrix-assisted laser desorption/ionization time of flight (MALDI-TOF)-mass spectrometric analysis and gel electrophoresis and characterized the lens nucleus morphology using electron microscopy (EM). The relative abundance of histone H3 protein decreased in lenses from cryaa-R49C mutant mice and the relative abundance of histone H2 increased in these lenses. Electron microscopy of nuclei from cryaa-R49C-homozygous mutant mouse lenses revealed a pronounced alteration in the distribution of heterochromatin.

Crystallin

10.1186/s13104-020-05154-7

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Comparison of the behavior of natural and refilled porcine lenses in a robotic lens stretcher

Experimental Eye Research (2008)

Matthew A. Reilly Paul D. Hamilton Gavin Perry Nathan Ravi

Presbyopia

10.1016/j.exer.2008.10.021

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Citations (30)