(1968). Studies on Oral Enzymes VII. Pyridoxal-5-Phosphae Dependent Cleavage of L-Cystine and Related Compounds by Enzyme Preparations from Human Oral Cavity and Certain Microoganisms. Acta Odontologica Scandinavica: Vol. 26, No. 5, pp. 443-471.
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTThe Bacterial Degradation of Pantothenic Acid. II. Pantothenate Hydrolase*Veikko Nurmikko, Esko Salo, Heikki Hakola, Kauko Mäkinen, and Esmond E. SnellCite this: Biochemistry 1966, 5, 2, 399–402Publication Date (Print):February 1, 1966Publication History Published online1 May 2002Published inissue 1 February 1966https://pubs.acs.org/doi/10.1021/bi00866a002https://doi.org/10.1021/bi00866a002research-articleACS PublicationsRequest reuse permissionsArticle Views83Altmetric-Citations12LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts
The effect of sorbitol (SOR), xylitol (XYL), and the mixture XYL/SOR in chewing gums on dental plaque was studied in three groups of 7 adults (mean age 22.5 years). A fourth group of habitual users of sucrose-containing gums was used as a control. The study involved a 2-week, no-gum period followed by the use of the polyol gums for 2 weeks (10 gums/day in 5 2-gum doses). The daily consumption of XYL and SOR in the XYL and SOR groups was 10.9 g, whereas in the XYL/SOR group, 8.5 and 2.4 g of these polyols were used per day. At the end of the gum period the acidogenic response of the 48-hour plaque was tested using a 10-ml mouthrinse containing the polyols (10% w/v) present in the experimental gums, followed by a 10-ml rinse of 10% (w/v) sucrose solution. The plaque of the subjects who used XYL and XYL/SOR gums showed a significantly better ability to resist pH drops induced by the sucrose rinse than the plaque in the SOR gum group. No changes in resting pH values were observed in the XYL and XYL/SOR groups, whereas the use of SOR gum was associated with significantly lower pH values. The amount of plaque decreased in the XYL/SOR (24.3%) and the XYL (29.4%) groups, but increased in the SOR (48.3%) group, the changes in the SOR group differing significantly from those found in the other groups. The plaque and saliva levels of Streptococcus mutans generally increased in the SOR group, but decreased in groups which used XYL.
AbstractAminopeptidase activity of normal and mechanically strained rat gingiva was studied using various N-L-aminoacyl-2-naphthylamine derivatives as substrates. Mechanical occlusal strain was directed to the first and second molar. The healing was studied 1, 3, 8 and 12 hours after the treatment. The mechanical treatment caused the disappearance of a gingival aminopeptidase which was inhibited by 0.2 M NaCl. This enzyme reappeared in the eight hour samples. All tissue samples (of the strained and control tissue) contained an enzyme so closely related to the rat liver aminopeptidase B (APB) that the presence of a true APB in rat gingiva was considered to be very likely. The activity of APB increased during the first hours, but this took place almost equally in both control and strained tissue, an indication that the strong mechanical treatment had also affected the control tissue of the test animals. The mechanical treatment used led to disturbances in the content of the studied enzymes in gingiva. The healing of the tissue, however, restored the initial situation within eight or twelve hours.Key Words: Aminopeptidasesgingivatissue injury
