Carbonell Lf

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Genetic engineering of viral pesticides: expression of foreign genes in nonpermissive cells.

Carbonell Lf Miller Lk

Expression (computer science)

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Citations (1)

[Hemodynamic changes in the acute phase of experimental hypertension].

PubMed (1983)

Carbonell Lf Jorge D. Salazar Joaquín García‐Estañ Jiménez Huelva Jl T. Quesada

The arterial pressure, heart rate, cardiac output, stroke volume, total peripheral resistance and plasma angiotensin II were measured in Wistar rats and 24 hours after arterial renal constriction by a clip (0.20 mm d.i.). The results were compared with those obtained in a sham operated group. The experimental group showed an increase in arterial pressure and total peripheral resistance without changes in heart rate, cardiac output and stroke volume. In hypertensive animals there was a greater level of plasma angiotensin II than in control group. These studies have demonstrated that 24 hours after renal arterial stenosis the increase in arterial pressure can be mediated by an increased activity of the renin-angiotensin system.

Peripheral resistance

Plasma renin activity

Mean arterial pressure

Constriction

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Citations (1)

[Participation of the renin-angiotensin system in experimental renovascular hypertension].

PubMed (1983)

Salazar Fj Joaquín García‐Estañ Carbonell Lf Muñoz Ja Miguel Montes Canteras

Hypertension was induced in Wistar rat by means of a clip in the left renal artery. After two weeks (acute stage) and sixteen weeks (chronic stage) the animals had a significant increase in arterial pressure (AP) and plasma renin activity (PRA). At both stages, nephrectomy or revascularization of the ischemic kidney returned AP and PRA to the normal level, both in the short term (1 day) and long term (60 days).

Renovascular Hypertension

Plasma renin activity

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Citations (2)

Normal hemodynamic parameters in conscious Wistar rats.

PubMed (1985)

Carbonell Lf Salom Mg Salazar Fj Joaquín García‐Estañ Mariano Ubeda

The evolution of different hemodynamic parameters with ponderal growth has been studied in conscious Wistar rats. The thermodilution method has been used to determine cardiac output and related variables. The results suggest that, between animal weight and the different hemodynamic parameters, there is a direct proportional relationship to blood volume, mean arterial pressure, cardiac output, stroke volume and total peripheral resistance, and an indirect proportional relationship to heart rate, cardiac index and stroke volume index. Body weight, therefore, plays a major role in hemodynamic determination, this having to be kept in mind when designing the experiment.

Peripheral resistance

Cardiac index

Mean arterial pressure

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Citations (5)