Süleyman Hilmi Aksoy

İstanbul Galata Üniversitesi

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Işıl Yurdaışık

Istinye University

BÇ

Basri Çakıroğlu

İstanbul Galata Üniversitesi

Tuncay Taş

İstanbul Nişantaşı Üniversitesi

Lora Ateş

Istanbul University

Orhun Sinanoğlu

University of Health Sciences Antigua

Ramazan Gözüküçük

Galatasaray University

Fuad Nurili

Istinye University

Mustafa Bahadır Can Balci

Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi

Ayse Gul Agirman

Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi

Hasan Kılıç

Doğuş University

Cooperative Institutions

Istanbul University

Galatasaray University

Istanbul University-Cerrahpaşa

Marmara University

Taksim German Hospital

Istinye University

Dr. Siyami Ersek Göğüs Kalp Ve Damar Cerrahisi Eğitim Ve Araştırma Hastanesi

Trakya University

Gaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi

Memorial Sloan Kettering Cancer Center

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Ionizing Radiation Exposure due to Medical Imaging in Hematopoietic Stem Cell Transplant Recipients

İstanbul medical journal (2022)

Süleyman Hilmi Aksoy Işıl Yurdaışık Ayşen TİMURAĞAOĞLU

Introduction:The study aimed to quantify the ionizing radiation exposure of patients with hematologic malignancy who underwent hematopoietic stem cell transplantation (HSCT).Methods: This was a retrospective evaluation of the adult patients who underwent allogeneic or autologous HSCT for hematologic malignities in a single center between January 2016 and September 2020.All radiological imaging procedures involving ionizing radiation screened study participants.The study period covered both the pre-and post-transplantation phases.A typical cumulative effective dose (CED) was used to calculate the exposed ionizing radiation in units of millisieverts (mSv).Results: A total of 120 patients (females 38.3%, mean age: 52.2±15.6 years) were included.Autologous HSCT was performed in 66 patients (55%), whereas 54 patients (45%) underwent allogeneic HSCT.Patients with acute myeloid leukemia and acute lymphoblastic leukemia comprised 53.7% and 31.5% of allogeneic HSCT, respectively.Autologous HSCT was mainly performed in patients with multiple myeloma (47%) and non-hodgkin lymphoma (34.8%).The median total CED was 11.85 mSv (interquartile range: 4.08-19.78).The median CED of allogeneic HSCT patients was significantly higher than that of the autologous HSCT group.The vast majority of the total CED (92.3%) comes from computed tomography imaging procedures.In the entire groups, 92 patients (76.7%) received a low dose (<20 mSv), whereas 26 patients (21.7%) received a moderate dose (>20-50 mSv) ionizing radiation.Conclusion: One-third of all HSCT patients received a moderate ionizing radiation dose.Allogeneic HSCT patients had significantly higher median CED than autologous counterparts.

Hematopoietic stem cell

10.4274/imj.galenos.2022.40771

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May Hepatic Steatosis Be Associated with Gynecomastia and Epicardial Fat? A Retrospective Study of 599 Male Patients

Bakirkoy Tip Dergisi / Medical Journal of Bakirkoy (2022)

Süleyman Hilmi Aksoy Selami Aydın Işıl Yurdaışık Orhan Dalkılıç

Objective: There is no study in the literature investigating the association of hepatic steatosis both gynecomastia and epicardial fat thickness together.We determined the correlations between hepatic steatosis through liver density, gynecomastia and epicardial fat thickness in patients undergoing computed tomography (CT) scans due to suspected coronavirus disease-2019 (COVID-19) symptoms.Methods: A total of 599 male patients who underwent chest CT scans because of a presumed diagnosis of COVID-19 in our radiology clinic were included in the study.Patients' age, diameters of the subareolar glandular tissues of the right and left breasts, the right retroareolar fatty tissue, liver and spleen density, epicardial fat thickness and biochemical parameters were recorded and analyzed.Laboratory analyses were performed according to the standard methods. Results:The mean age of the patients was 47.21±15.00years.The left subareolar tissue thickness and the right retroareolar fatty tissue thickness that are used to indicate gynecomastia were significantly correlated with liver density in the negative direction (r=-0.137,p<0.001; r=-0.172,p<0.001; respectively).Epicardial fat thickness was statistically significantly correlated with right subareolar tissue thickness (r=0.085,p=0.037), left subareolar tissue thickness (r=0.101,p=0.014) and right retroareolar fatty tissue thickness (r=0.148,p<0.001). Conclusion:The results of this study showed that gynecomastia was significantly correlated with both age and hepatic steatosis.Epicardial fat thickness is also associated with hepatic steatosis.We demonstrated the significant correlations between epicardial fat thickness and gynecomastia for the first time.Nevertheless, our results need to be confirmed by further comprehensive studies.

Steatosis

Gynecomastia

Epicardial Fat

10.4274/bmj.galenos.2022.2022.3-8

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Opinions of patients related to radiology department during the COVID-19 pandemic

The Annals of Clinical and Analytical Medicine (2021)

Işıl Yurdaışık Süleyman Hilmi Aksoy

Aim: Patients experience tension due to the measures that should be taken against the COVID-19 pandemic in radiology departments.The objective of this study was to measure the opinions of patients related to the radiology department during the pandemic.Material and Methods: The survey developed by the researcher in line with the current literature was applied to measure the satisfaction of patients in the radiology department.The survey consisted of 26 questions, the first six of which involved demographic characteristics.The survey was conducted with a face-to-face interview method.Results: The study included 300 patients referred to the radiology department due to any reason and who were voluntarily participated.The responders answered the questions that "Did you get information about your radiology examination before your appointment?" as "no" by 78%, "Did you have any questions to radiology department staff after your examinations?" as "yes" by 26% and "Did the staff of the radiology department and/or the radiologist take the time to answer your questions?" as "no" by 60.4%.The overall rate of satisfaction with the services delivered in the radiology department was found as 95%.Discussion: Our survey shows that as high as 95% of the patients who were referred to the radiology department for imaging for any reason were satisfied with the radiology department during the pandemic.Such satisfaction surveys in departments such as radiology, where patients have limited access to staff, especially radiologists, provide valuable feedback to clinicians and other healthcare providers.

Pandemic

2019-20 coronavirus outbreak

10.4328/acam.20454

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Postmortem Biopsies of the Lung, Heart, Liver, and Spleen of COVID-19 Patients

Authorea (Authorea) (2021)

Işıl Yurdaışık Ahu Senem Demiröz Büğe Öz Mustafa Akker Ayse Gul Agirman

Objective: We aimed to evaluate histopathologic alterations in the lung, heart, liver, and spleen of coronavirus disease 2019 (COVID-19) decedents through postmortem core needle biopsies. Materials and Methods: Patients who died of reverse transcription-polymerase chain reaction-proven COVID-19 were included in this postmortem case series. Postmortem percutaneous ultrasound-guided biopsies using 14- and 16-gauge needles were performed in the lungs, heart, liver, and spleen. Biopsy samples were stained with hematoxylin-eosin and examined under a light microscope. Clinicodemographic characteristics, chest computed tomography (CT) images, and COVID-19-related treatments of the patients were also collected. Results: Seven patients were included in this study. Liver and heart tissue samples were available from all patients, and lung and spleen tissues were available from five and three patients, respectively. Chest CT images predominantly revealed bibasilar ground-glass opacities. Lung biopsies showed diffuse alveolar damage in all biopsy specimens. Heart findings were nonspecific and largely compatible with the underlying disease. Patchy necrosis, steatosis, and mononuclear cellular infiltration were the main findings in the liver biopsies. Splenic histopathological examination showed that splenic necrosis and neutrophil infiltration were the common findings in all patients. Conclusion: Tissue acquisition was complete for the heart and liver and acceptable for lungs. The amount of tissue was sufficient for a proper histopathologic examination. The histopathological findings were generally in accordance with previous autopsy studies. The lung radiological findings were also correlated with the histopathologic findings. We consider that a postmortem biopsy is a feasible alternative for histopathological examinations in COVID-19 decedents.

Histopathology

Diffuse alveolar damage

Infiltration (HVAC)

10.22541/au.161987421.18062832/v1

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Renal Kolikli hastalarda bilgisayarlı tomografi ile ultrasonagrafi bulgularının karşılaştırılması

Basri Çakıroğlu S. Erkan Eyüpoğlu Abdussamet Hazar Mahi Balcı Orhun Sinanoğlu

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Valsalva computed tomography in visualization of Eustachian tube in patients with patulous Eustachian tube

Authorea (Authorea) (2021)

Süleyman Hilmi Aksoy Yavuz Selim Yıldırım Işıl Yurdaışık

Abstract Objectives: There is no study in the literature that patients with clinically-proven PET were evaluated by Valsalva CT. We aimed to evaluate the merit of Valsalva computed tomography (CT) in patients who had clinically-proven patulous Eustachian tube (PET). Design: Case-series Setting and participants: We recruited patients with clinically-proven PET. Participants: Main outcome measures: All participants underwent temporal bone CTs while they were performing the Valsalva maneuver in the supine position. Standard axial plane CT images, along with multiplanar reconstruction and 3D Air volume rendering, were used to visualize the ET in its entirety. Results: Three patients (2 females, one male) with a total of 6 ears were included in the study. All patients had suggestive symptoms of PET, including aural fullness, aerophony, and autophony and underwent clinical examination and audiologic tests. In all ears, the whole Eustachian tube could be visualized with Valsalva CT. Conclusion: For the first time, we demonstrated the merit of Valsalva CT in visualization of the Eustachian tube in its entirety in patients with clinically diagnosed PET.

Valsalva maneuver

Eustachian tube

Supine position

10.22541/au.161212162.29219261/v1

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Renal papillary attenuation differences between primary and recurrent idiopathic calcium stone disease patients.

PubMed (2014)

Basri Çakıroğlu S E Eyyupoglu Tuncay Taş Tarık Esen Ömer Acar

The aim of this paper was to investigate whether renal papillae of patients with nephrolithiasis are more radiodense than that of control patients and to evaluate the predictability of urolithiasis using papillary density differences between stone and non-stone formers.Renal papillary Hounsfield Unit (HU) measurements were conducted at the level of upper pole, middle region and lower pole of both kidneys in a total of 126 primary (group 1), 133 recurrent (group 2) stone disease patients and 108 controls (group 3).Mean patient age did not differ significantly between groups (P>0.05). Mean stone diameters (±SD) were 5.0±3.1 mm (3-9 mm) and 6.1±3.3 mm (3-15 mm) for primary and recurrent groups, respectively and group distributions and variances were similar (P>0.05). Mean papillary attenuation values (±SD) were 27.26±9.30 (4.00-56.00) in group 1, 30.42±9.88 (12.00-64.00) in group 2 and 25.83±2.72 (20.30-32.56) in the control group. The difference between the mean papillary attenuation value of the primary stone disease group and the control group was statistically insignificant (P=0.104). When the control group and the recurrent stone group was compared without variances, in terms of the mean renal papillary attenuation value, a statistical significance was achieved (P=0.000).With increasing renal papillary HU values, the risk of recurrent calcium stone disease is increased.

Hounsfield scale

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Urachal Actinomycosis Presenting with Recurrent Urinary Tract Infections in a Middle-aged Woman: A Rare Case Report

Journal of College of Physicians And Surgeons Pakistan (2022)

Basri Çakıroğlu Cevdet Kaya Süleyman Hilmi Aksoy Ramazan Gözüküçük Lora Ateş

The urachal cyst, a remnant of allantois sac during embryogenesis, is a rare condition in adulthood. Urachus is an embryologic remnant degenerating after birth. Abberrant obliteration of the urachus causes urachal abnormalities. The urachal cysts are almost always symptomatic when infected. The symptoms include fever, abdominal pain, tenderness, lower abdominal mass, nausea, vomiting, and dysuria. Ultrasonography, computerised tomography, and magnetic resonance imaging techniques may be insufficient for diagnosis. In most cases, staphylococcus species are isolated from cultures of urachal cysts. Other microorganisms such as Escherichia coli, Enterococcus faecium, Klebsiella pneumonia, and rarely actinomyces may be isolated. Actinomyces, an anaerobic gram-positive filamentous bacterium, is a rare cause of granulomatous disease. In this case report, a 56-year woman with urachal cyst infection with actinomyces is discussed according to current knowledge. Key Words: Urachal cyst, Urachus, Chronic cystitis, Actinomyces.

Urachus

Actinomyces israelii

Actinomycosis

Abdominal ultrasonography

10.29271/jcpsp.2022.05.668

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Myxolipoma of the renal capsule: A case report

International Journal of Surgery Case Reports (2014)

Basri Çakıroğlu Tuncay Taş Tarık Esen Lora Ateş Süleyman Hilmi Aksoy

Although lipomas are the most common mesenchymal tumors of the human body, primary intrarenal lipomas are quite rare. In this report we present a case of benign mesenchymal tumor with lipomatous and myxoid components. A sixty one years old male patient was admitted to our outpatient clinic for a general control since he had a right radical nephrectomy operation due to renal cell carcinoma (RCC) eight years ago and he did not have any urological control for last 3 years. However the urinary ultrasound revealed a mass lesion on left kidney and then on axial contrast-enhanced computed tomography (CT) scan, there were two masses on the left kidney. In the magnetic resonance imaging (MRI), the tumor on cortex was depicted as a homogeneous low-signal intensity on the T1-weighted pulse sequence and as a heterogeneous high-signal intensity on the T2-weighted pulse sequence. In pathological evaluation, the biopsy material of the cortical mass was a tumoral lesion containing lipomatous and mixoid areas without atypia, mitosis or necrosis which was diagnosed as myxolipoma. Myxolipoma, an uncommon type of lipoma, is a benign tumor composed mainly of fat cells with myxoid (mucus-like) components. In our case, the tumor was composed of mature adipocytes together with areas rich in mucoid substances and there were no malignant features including lipoblasts, mitosis or abundant capillary network. Herein we present a case of a fatty tumor originating from the renal capsule with the histologic diagnosis of myxolipoma. To the best of our knowledge, myxolipoma, a very rare form of lipoma, is not reported in kidney, in the literature before.

Atypia

Renal capsule

Renal cortex

10.1016/j.ijscr.2014.09.011

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Pelvikalisiyel anatominin alt pol kaliks taşlarının tedavisinde retrograd intrarenal cerrahinin başarısına etkisi

İstanbul Kanuni Sultan Süleyman Tıp Dergisi (2022)

Süleyman Hilmi Aksoy

10.14744/iksstd.2022.25593

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