Nasibah Mohamad

Universiti Sains Malaysia

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Bazli Md Yusoff

Hospital Universiti Sains Malaysia

Chandran Nadarajan

Hospital Universiti Sains Malaysia

Khairil Amir Sayuti

Universiti Sains Malaysia

Fatin Syahirah Sulaiman

Hospital Universiti Sains Malaysia

Mohd Shafie Abdullah

Universiti Sains Malaysia

Mohd Hafizuddin Husin

Hospital Universiti Sains Malaysia

Zaıdı Zakarıa

Universiti Sains Malaysia

V Sha Kri Eh Dam

Universiti Sains Malaysia

Norzaliana Zawawi

Universiti Sains Malaysia

Ganeshwara Lingam

Hospital Kuala Lumpur

Cooperative Institutions

Universiti Sains Malaysia

Hospital Universiti Sains Malaysia

Hospital Kuala Lumpur

Sultan Zainal Abidin University

Royal London Hospital

University College London

Research Institute of Radiology

University School of Milwaukee

Universiti Putra Malaysia

University Health Network

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Dizziness and syncope after subclavian steal: A case report of a rarely symptomatic, common vascular disorder

Malaysian Family Physician (2022)

Nik Mohamed Firdaus Nik Mohamed Kamal Nasibah Mohamad Bazli Md Yusoff

Subclavian steal syndrome (SSS) is a manifestation of vertebrobasilar artery insufficiency due to stenosis of the proximal subclavian artery. It is a common vascular disorder; however, most patients are asymptomatic, and the disorder is commonly found incidentally during imaging. Nevertheless, some patients may present with arm ischemia or signs and symptoms of vertebrobasilar insufficiency, such as vertigo, dizziness, diplopia, ataxia, dysarthria, and syncopal episodes. We present a case of a male patient who presented with sudden onset dizziness, syncopal episodes, and blood pressure discrepancy between his arms. Diagnosis was a challenge, and the patient underwent several investigations, including basic bloodwork, electrocardiography (ECG), echocardiography, brain computed tomography (CT), and coronary CT angiography (CTA). Narrowing in the proximal left subclavian artery was found during coronary CTA, which confirmed the diagnosis of SSS.

Subclavian steal syndrome

Vertebrobasilar insufficiency

10.51866/cr1306

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Successful transcatheter embolization of splenic artery pseudoaneurysm in acute necrotising pancreatitis.

The Interventionalist Journal (2021)

Nasibah Mohamad Fatin Syahirah Sulaiman Norhafizah Ehsan Izazul Hussin

Splenic artery pseudoaneurysm is a rare condition commonly arises as a sequelae of pancreatitis. Pseudoaneurysm is clinically silent until it ruptures. Thus, untreated pseudoaneurysm carries a high mortality rate up to 90%. We present a case of necrotising pancreatitis complicated with unruptured splenic artery pseudoaneurysm, which was found incidentally from computed tomography (CT) of abdomen. Patient was presented with symptomatic anemia and bleeding from the abdominal drain. We proceeded with embolization of pseudoaneurysm by using Histoacryl glue, resulting in successful complete resolution of pseudoaneurysm with good patient outcome. Transcatheter embolization is considered the current treatment of choice for pseudoaneurysm as it provides an alternative to conventional surgery due to its high successful rate. In this case report, we want to shed light on an alternative treatment approach of the splenic artery pseudoaneurysm.

Pseudoaneurysm

10.32896/tij.v1n2.7-11

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Diffusion tensor imaging (DTI) studies of cerebral white matter integrity in normal to moderate cardiovascular risk patients

Deleted Journal (2023)

Nasibah Mohamad Khairil Amir Sayuti Muzaimi Mustapha

Background & Objectives: The cerebral small vessel disease (CSVD) manifest as white matter lesion (WML) in magnetic resonance imaging (MRI). The diffusion tensor imaging (DTI) study shows a lower white matter integrity in white matter lesion (WML) and its penumbra region, suggesting cerebral white matter damage. The aim of this study is to establish correlation between the DTI values of white matter with the age related white matter changes (ARWMC) visual rating score and identify predictors of ARWMC score. Methods: 63 brain MRI images of subjects were selected. Relevant clinical information of the subjects which satisfied QRISK2 risk factors were retrieved from the patients’ folder. DTI parameters were obtained via postprocessing at OsiriX DTImap workstation. Results: FA frontal (r = -0.36; p = 0.003) and AD frontal (r = -0.26; p = 0.040) had a substantial and negative correlation with the ARWMC score. There was a significant positive correlation shown between the ARWMC score and RD frontal (r = 0.30; p = 0.018). There were positive significant association between the ARWMC score and age (b(95%CI): 0.106 (0.061, 0.151); p<0.001) and QRISK2 score (b(95%CI): 0.235 (0.036, 0.433)). Conclusion: DTI is a good method to study the cerebral white matter integrity. It was found that frontal lobe is the first region affected in relation to ageing, in particular the myelin integrity. Increasing age and higher QRISK2 cardiovascular risk factors were shown to increase the ARWMC score.

Frontal lobe

10.54029/2023zvk

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Neglected Retained Central Venous Catheter Guidewire Complicated With Guidewire Rupture During Retrieval Process And Its Bailout Technique

The Interventionalist Journal (2022)

Mohd Ab Hakim Ibrahim Mohd Hafizuddin Husin Nasibah Mohamad Bazli Md Yusoff Chandran Nadarajan

Central venous catheter insertion is a commonly performed procedure. This catheter is used to administer drugs and fluid, especially in critically ill patients, and monitor central venous pressure. We present a case of a retained guidewire for 17 months which was found incidentally from the abdominal and chest radiograph. We retrieved the retained J-tip guidewire using four loops retrieval snare. The retrieval process was complicated with the rupture of the guidewire, causing the unwinding of its outer sphere, leaving the inner monofilament dangling in the heart chamber. In this case report, we would like to describe the initial retrieval technique, which was failed and its bailout procedure.

Central venous catheter

10.32896/tij.v2n2.10-15

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A case of concurrent gastrointestinal, peritoneal and urinary bladder tuberculosis

Indian Journal of Tuberculosis (2021)

Mohamad Firdaus Ahmad Nasibah Mohamad Nur Asma Sapiai Nor Adibah Razali Abdul Hadi Anuar

Urogenital tuberculosis

Extrapulmonary tuberculosis

10.1016/j.ijtb.2021.09.004

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A Large Substernal Goiter Mimicking Lung Mass

Asian Journal of Medicine and Biomedicine (2024)

Siti Fatima Azahraa Mohd Azha Nasibah Mohamad

Substernal goiter, also known as a retrosternal goiter, is defined as a thyroid mass that exhibit 50% or more of its volume located below the thoracic inlet. This enlarged thyroid gland grows inferiorly and passes through the thoracic inlet into the thoracic cavity. Substernal goiters are most descended into the anterosuperior mediastinum and may also extend into the posterior mediastinum behind the trachea or even into the posterior thoracic cavity. The appearance of this substernal goiter on chest radiograph may show smooth soft tissue mass which characteristically displaces the trachea. Here, we describe a rare case of a large substernal goiter in 53-year-old lady, who denied any obstructive symptoms or any noticeable thyroid swelling in the neck region. Incidentally, large mass was discovered on her right lung on chest radiograph during screening and she was considered to have a lung cancer at the first sight. Tomographic examination revealed a large mediastinal mass extending from the inferior pole of right thyroid lobe, compressing the lateral wall of trachea on the right upper lung region. Considering the large appearance of intrathoracic mass without much mediastinal structure deviation on conventional radiograph raise suspicion of lung cancer, thus computed tomography plays an important role in determining the origin of the mass.

Chest radiograph

Thoracic cavity

10.37231/ajmb.2024.8.2.782

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Rare Case of Acute Renal Artery Thrombosis in Nephrotic Syndrome: The Unusual Presentations and Outcomes of Endovascular Manual Aspiration Thrombectomy

University of Toronto Medical Journal (2024)

Fatin Syahirah Sulaiman Nasibah Mohamad Mohd Hafizuddin Husin Chiew Chea Lau Khairil Amir Sayuti

Renal artery thrombosis is a rare condition that requires early diagnosis and urgent intervention to prevent renal infarction and permanent renal damage. Possibility of renal artery thrombosis should be considered in patients with underlying hypercoagulable state presented with acute unremitting flank pain, nausea and vomiting. We report a case of a 35-year-old man with underlying nephrotic syndrome who presented with three days history of acute non-localized and non-resolving abdominal pain and vomiting. He was initially referred to general surgery for acute intestinal obstruction. Contrast-enhanced computed tomography (CECT) abdomen revealed acute left renal infarction secondary to total thrombotic occlusion of the left renal artery. The patient was treated with endovascular manual aspiration thrombectomy resulting in partial revascularization of left renal artery with restoration of renal function, complete resolution of symptom and good clinical outcomes. This case report serves as a reminder for physicians to include renal infarction in the differential diagnosis when evaluating a patient with acute abdomen, particularly in patient with hypercoagulable state. This case also aligns with other experiences demonstrating positive outcomes after endovascular thrombectomy, even in the presence of prolonged renal ischemia time of more than 72 hours.

10.33137/utmj.v101i1.41619

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Cerebellar hemorrhage in a healthy young adult: a case report

Journal of Medical Case Reports (2022)

Al Hafiz Ibrahim Nasibah Mohamad T. A. Mohd Yusof Rasid M. S. Abdullah

Abstract Background Cavernous venous malformation is an uncommon entity that occurs in around 0.5% of the general population. Cerebellar cavernous venous malformation accounts for 1.2–11.8% of intracranial cavernous venous malformation cases. Patients are commonly asymptomatic until a hemorrhage occurs. In approximately 20% of the cases, cavernous venous malformation and developmental venous anomalies occur together, called mixed vascular malformation. Our case report reveals the imaging features of the mixed vascular malformation and highlights the appropriate imaging modality and sequence to detect the abnormalities. Case presentation We report the case of a 15-year-old Malay male, a healthy young male who presented with dizziness, vomiting, and mild headache for 1 month. Computed tomography brain imaging at presentation revealed cerebellar hemorrhage with multiple cavernous venous malformation and coexisting developmental venous anomalies, which was then confirmed by magnetic resonance imaging. The patient was started on dexamethasone 4 mg four times a day, observed in the ward, and discharged well without neurological sequelae. Conclusion A cavernous malformation with concurrent developmental venous anomalies requires accurate diagnosis. Our case report contributes to the literature on the imaging diagnosis of this disease, which is beneficial for current and future reference.

Venous malformation

Cavernous malformations

Vascular malformation

Arteriovenous malformation

Presentation (obstetrics)

Intraparenchymal hemorrhage

10.1186/s13256-022-03584-4

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A Case Report of a Rare Form of VACTERL Association

Asian Journal of Medicine and Biomedicine (2024)

Siti Fatima Azahraa Mohd Azha Nasibah Mohamad

VACTERL association is an acronym describing a series of abnormal clinical characteristics that occur together. The abnormalities are vertebral defect (V), anal atresia (A), cardiac defect (C), tracheoesophageal fistula (TE), renal anomalies (R) and limb defect (L). VACTERL association with hydrocephalus, known as VACTERL-H, carry poor prognosis compared to classical VACTERL. We reported a rare case of VACTERL-H with tracheal bronchus, a rare tracheobronchial airway anomaly complicated with recurrent pneumonia and bronchiolitis obliterans. This case highlights the importance of diagnosing tracheobronchial pulmonary anomalies as they contribute to recurrent pneumonia and atelectasis.

Anal atresia

Tracheoesophageal Fistula

Atelectasis

10.37231/ajmb.2024.8.2.753

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Advanced Nasopharyngeal Carcinoma with Generalized Lymphadenopathy Masquerade as Lymphoma.

PubMed (2022)

V Sha Kri Eh Dam Nasibah Mohamad Izyan Rifhana Muhamad Al Duais Saleh Abdul Kadir Saeed Wan Faiziah Wan Abdul Rahman

Nasopharyngeal carcinoma (NPC) is a nasopharyngeal epithelial neoplasm that has distinct aetiological, epidemiological and biological characteristics compared to other head and neck malignancies. Patients usually present late due to non-specific symptoms and deep location of the tumour in the nasopharynx.We would like to highlight a case of advanced NPC presenting with generalised lymphadenopathy, without the presence of an obvious nasopharyngeal mass that masqueraded as lymphoma in the initial stage.NPC may share clinical features with other sinonasal pathologies or other malignant lymphoproliferative disorders that lead to a delay in diagnosis. NPC should be one of the differential diagnoses for any cases presenting with cervical lymphadenopathy, especially in adult male patients originating from East or Southeast Asia. Early diagnosis and treatment are crucial because early-stage NPC has an excellent chemoradiotherapy response and high survival rate.

Cervical lymphadenopathy

Etiology

Cervical lymph nodes

Lymphoproliferative Disorders

Malignant lymphoma

10.22038/ijorl.2022.62088.3133

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