A method for calculating accelerational pressure drop in two-phase compressible gas-liquid flow has been developed. Knowing this pressure drop is important in the design and analysis of high-velocity compressible flow systems such as flare networks where critical two-phase flow may occur. This article sets out a simple relationship between critical mass flux and accelerational pressure drop for single phase and two-phase compressible flow in oil and natural gas pipelines. Based on this relationship and on the Moody model for critical flow, the new method for calculating acceleration pressure drop was developed.