Colleen M. Cebulla

The Ohio State University Wexner Medical Center

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Trends

Author Order

Document Type

Co-Authors

Mohamed H. Abdel‐Rahman

The Ohio State University Wexner Medical Center

Robert Pilarski

Ambry Genetics (United States)

Frederick H. Davidorf

The Ohio State University Wexner Medical Center

Lynn Schoenfield

The Ohio State University Wexner Medical Center

Karan Rai

The Ohio State University

Marc‐Henri Stern

Inserm

Hui Shen

The University of Texas MD Anderson Cancer Center

Christopher C. Benz

Buck Institute for Research on Aging

Katherine A. Hoadley

University of North Carolina at Chapel Hill

Andrew D. Cherniack

Broad Institute

Cooperative Institutions

National Institutes of Health

253

The University of Texas MD Anderson Cancer Center

242

Harvard University

221

The Ohio State University

198

Washington University in St. Louis

163

Baylor College of Medicine

154

University of Miami

147

The Ohio State University Wexner Medical Center

138

Memorial Sloan Kettering Cancer Center

134

Dana-Farber Cancer Institute

114

Author Statistics

Papers

Citation

H-Index

i-10 index

Research Field

My Virtual Cancer

Leili Shahriyari Mohamed H. Abdel‐Rahman Alireza Asadpoure Colleen M. Cebulla ying xian chang

Since each cancer has its own unique characteristics, each one can respond differently to the same treatments. Therefore, the creation of a digital twin (DT) of cancer can assist us in predicting the evolution of an individual's cancer through modeling each tumor's characteristics and response to treatment. Hence, we propose to take advantage of new advances in computational approaches and combine mechanistic, machine learning, and stochastic modeling approaches to create “My Virtual Cancer", a DT platform. To establish a personalized DT, we use patient-specific data for parameter estimations, sensitivity analysis, and uncertainty quantification. For each patient, we will estimate the values of parameters of their QSP model using the patient's data. We perform a multi-dimensional sensitivity analysis and uncertainty quantification on the mechanistic model to find a set of critical interactions and predict the intervals of confidence. Since this QSP model includes the data-driven mechanistic model of cells and molecules' interaction networks, one of the ultimate results of this DT would be the prediction of evolution of tumors.

10.2172/1881930

Cite

Citations (0)

Whole Exome Sequencing Identifies Candidate Genes Associated with Hereditary Predisposition to Uveal Melanoma

Ophthalmology (2019)

Mohamed H. Abdel‐Rahman Klarke M. Sample Robert Pilarski Tom Walsh Timothy W. Grosel

CHEK2

MSH6

PALB2

MLH1

BAP1

Proband

10.1016/j.ophtha.2019.11.009

Cite

Citations (35)

Contributors

Elsevier eBooks (2019)

Mohamed H. Abdel‐Rahman Elizabeth D. Au Milam A. Brantley Kinga M. Bujakowska Colleen M. Cebulla

10.1016/b978-0-12-816222-4.09992-5

Cite

Citations (0)

Bilateral optic neuropathy following bite from brown recluse spider (Loxosceles reclusa)

Cutaneous and Ocular Toxicology (2015)

Dimosthenis Mantopoulos Andrew Hendershot Colleen M. Cebulla David K. Hirsh

A 63-year-old female with history of a resected frontal lobe meningioma presented with bilaterally decreased vision after a bite from a brown recluse spider. The exam was significant for a left relative afferent pupillary defect, bilateral optic nerve pallor, decreased foveal sensitivity in the left eye and new bilateral visual field defects, despite stability of her meningioma. The findings remained stable at 1-year follow-up. To our knowledge, this is the first reported case of optic neuropathy secondary to a brown recluse spider bite. Visual field tests performed prior to the bite allowed us to compare and localize changes related to the bite.

10.3109/15569527.2015.1027906

Cite

Citations (4)

The effect of MIF inhibitor ISO-1 on apoptosis in chick retinal damage model

Investigative Ophthalmology & Visual Science (2017)

Rania Kusibati Bongsu Kim Tyler Heisler‐Taylor Levi Todd Andy J. Fischer

Source

Cite

Citations (0)

An overview of BAP1 biological functions and current therapeutics

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer (2025)

Abdelrahman M. Elsayed Muaiad Kittaneh Colleen M. Cebulla Mohamed H. Abdel‐Rahman