Minecoside and verminoside, two new iridoid glucosides from Veronica officinalis L. ( Scrophulariaceae ) Two new esters of catalpol, minecoside ( 1 ) and verminoside ( 3 ), have been isolated from Veronica officinalis L. The structures of 1 and 3 have been determined on the basis of the spectral data as 6‐isoferuloylcatalpol and 6‐caffeeoylcatalpol, respectively.

Scrophulariaceae

Catalpol

10.1002/hlca.19790620221

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Citations (52)

Rapid and sensitive determination of dehydroascorbic acid in addition to ascorbic acid by reversed-phase high-performance liquid chromatography using a post-column reduction system

Journal of Chromatography A (1987)

S. J. Ziegler Beat H. Meier Otto Sticher

Dehydroascorbic acid

Dithiothreitol

10.1016/s0021-9673(01)94343-2

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Citations (48)

Quinolizidine Alkaloids from the Curare Adjuvant Clathrotropis glaucophylla.

ChemInform (2003)

Anne‐Lise Sagen Jürg Gertsch Rita Becker Joerg Heilmann Otto Sticher

Abstract For Abstract see ChemInform Abstract in Full Text.

Quinolizidine

Curare

10.1002/chin.200317183

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Citations (0)

Lavandulifolioside: A New Phenylpropanoid Glycoside from Stachys lavandulifolia

Helvetica Chimica Acta (1988)

Arif Ahmet Başaran İhsan Çalış Clemens Anklin Sansei Nishibe Otto Sticher

Abstract A new phenlypropanoid glycoside has been isolated from the methanolic extract of the aerial parts of Stachys lavandulifolia (Lamiaceae), lavandulifolioside (1) . On the basis of chemical and spectral data the structure of the new compound 1 has been elucidated as β‐(3,4‐dihydroxyphenyl)ethyl O ‐α‐ L ‐arabinopyranosyl‐(1→2)‐α‐ L ‐rhamnopyranosyl‐(1→3)‐4‐ O ‐caffeoyl‐β‐ D ‐glucopyranoside.

Phenylpropanoid

10.1002/hlca.19880710612

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Citations (60)

ChemInform Abstract: New Dolabellane Derivatives from the Brown Alga Dictyota pardalis.

ChemInform (1992)

Anthony D. Wright Gabriele M. Koenig Otto Sticher Paolo Lubini Patrick Hofmann

Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.

10.1002/chin.199211226

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Citations (0)

An analytical high performance liquid chromatographic method for the determination of agnuside andp-hydroxybenzoic acid contents in Agni-casti fructus

Phytochemical Analysis (2000)

Eva Hoberg Beat H. Meier Otto Sticher

Gradient elution

Vitex

Chromatography detector

Solid phase extraction

10.1002/1099-1565(200009/10)11:5<327::aid-pca523>3.0.co;2-0

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Citations (22)

A Novel Extracellular Diterpenoid with Antibacterial Activity from the Cyanobacterium Nostoc commune

Journal of Natural Products (1999)

Birgit U. Jaki Jimmy Orjala Otto Sticher

A novel extracellular metabolite with an unprecedented diterpenoid skeleton, 8-[(5-carboxy-2-hydroxy)benzyl]-2-hydroxy-1,1,4a,7,8-pentamethyl-1,2,3,4,4a,6,7,8,8a,9,10,10a-dodecahydrophenanthrene, has been isolated from the culture medium of the terrestrial cyanobacterium Nostoc commune Vaucher (EAWAG 122b) by means of bioguided isolation. The molecule was designated as noscomin. The structure was determined by spectroscopic methods, mainly NMR and mass spectrometry. Noscomin exhibited antibacterial activity against Bacillus cereus, Staphylococcus epidermidis, and Escherichia coli.

Nostoc

10.1021/np980444x

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Citations (119)

An Nmr Study of Four Benzophenanthridine Alkaloids

Journal of Natural Products (1991)

S. M. Oechslin GM König K. Oechslin-Merkel A. D. Wright A. Douglas Kinghorn

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTAn Nmr Study of Four Benzophenanthridine AlkaloidsS. M. Oechslin, G. M. König, K. Oechslin-Merkel, A. D. Wright, A. D. Kinghorn, O. Sticher, and M. MiyagawaCite this: J. Nat. Prod. 1991, 54, 2, 519–524Publication Date (Print):March 1, 1991Publication History Published online1 July 2004Published inissue 1 March 1991https://pubs.acs.org/doi/10.1021/np50074a026https://doi.org/10.1021/np50074a026research-articleACS PublicationsRequest reuse permissionsArticle Views307Altmetric-Citations26LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose Get e-Alerts

Wright

Icon

10.1021/np50074a026

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Citations (34)

“PRISMA” Model for Computer-Aided HPLC Mobile Phase Optimization Based on an Automatic Peak Identification Approach

Journal of Liquid Chromatography (1991)

Szabolcs Nyiredy Werner Wosniok Herbert Thiele Otto Sticher

Abstract The tripartite "PRISMA" optimization model, as part of the "PRISMA" system, includes all possible solvent combinations between 1–4 solvents, with a possible fifth one as modifier. The solvent composition is characterized by the solvent strength (ST) and the selectivity points (PS). At a constant ST the correlation between the PS and the retention data (horizontal function) can be described by a quadratic function. For constant PS the solvent strengths and retention data correlate (vertical function) with a logarithmic function. These correlations are used to formulate a mathematical model for the dependence of retention times (capacity factor) on the mobile phase composition. Unknown compounds are estimated in the mathematical model from a sequence of standard chromatograms after having identified individual peaks by an automatic procedure. Only retention times, relative peak areas, and information about the mobile phase compositions are required as input for the identification approach. The approach involves a combination of statistical methods which exploit both the basic properties of retention data and the mathematical relation between retention data, selectivity points, and solvent strength as derived from the "PRISMA" model. Diagnostic information for checking the identification is generated as a by-product. The mathematical model completed by the estimated constants predicts the expected retention times for each possible mobile phase combination. Peak start and peak end times are predicted in a way similar to the retention times, once the identification has been performed. The most important aspects of a chromatogram can thus be predicted for arbitrary mobile phases. The separation quality of predicted chromatograms is assessed by the chromatographic response function (CRF). The optimal mobile phase combination is that which theoretically generates the chromatogram with the maximal CRF value. This optimal composition is found by a simple mathematical procedure, which maximises the CRF in dependence upon the mobile phase combination. The optimum found is a local one if the starting set of chromatograms contains no variation of the solvent strength, and a global one if, in the set of starting chromatograms, the solvent strength is varied in a suitable way. Recommendations for the starting position are given. Twelve measurements are necessary for a local optimum, and 15 for the global one. To increase the accuracy, six measurements at three different solvent strength levels are proposed. Generally the highest and the lowest solvent strength level differ by ±(5)% from the middle level. This strategy is also relevant when modifiers are used in constant amounts. The chromatographic behavior of substances to be separated can be predicted with 1% accuracy from correlations of k' values and selectivity points. Based on these relationships, an automatical mobile phase optimization strategy for isocratic separations is suggested with the "PRISMA" model.

Constant (computer programming)

10.1080/01483919108049377

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Citations (17)