Marjela Pernoci

St. Boniface Hospital

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Matteo Cameli

University of Siena

Massimo Bonacchi

University of Florence

Aleksander Dokollari

University of Manitoba

Didar‐Karan Kalra

St. Michael's Hospital

Subodh Verma

St. Michael's Hospital

Sandro Gelsomino

Maastricht University

Bobby Yanagawa

University of Toronto

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Lindita Çoku

Appalachian Regional Healthcare

M Demosthenous

Hippocration General Hospital

Mohammad Bin Pervez

Aga Khan University

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Hospital Clínic de Barcelona

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University of Pittsburgh Medical Center

University of Pittsburgh

Sağlık Bilimleri Üniversitesi

St. Michael's Hospital

University of Toronto

Harvard University

Lankenau Institute for Medical Research

Main Line Health

Cleveland Clinic

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Journal of Cardiac Surgery (2020)

Tessa Wa Shannon Msh Alexander A. Brescia David J. Burn Alex M. Wisniewski

to get the results it gets

10.1111/jocs.14113

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Development of a Risk Score for Long-term Survival and MACCE After Coronary Artery Bypass Grafting Surgery

The American Journal of Cardiology (2024)

Aleksander Dokollari Fabrizio Rosati Claudio Muneretto Andrea Amabile Marjela Pernoci

Stroke

10.1016/j.amjcard.2024.03.039

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Transcatheter aortic valve implantation in Italian women versus men: Single center comparison of baseline characteristics and report of clinical and procedural outcomes

Aleks er Dokollari Matteo Cameli Giulia Elena M oli

Objective: To compare the baseline characteristics and outcomes of Transcatheter Aortic Valve Implantation (TAVI) in Italian women and men. Background: Previous outcomes of TAVI between men and women are contradictory in different patient populations. Methods: Patients between 75-year old and 87-year old, who underwent TAVI between 2010 and 2016, were retrospectively analyzed. Results: 256 patients, 114 men and 142 women, were included in the analysis. Baseline characteristics displayed a higher incidence of smoking, myocardial infarction, chronic obstructive pulmonary disease, conduction abnormality, previous percutaneous coronary intervention, and surgery in men (p<0.05). Echocardiographic data evidenced higher transvalvular gradients, higher pulmonary artery pressures, lower aortic valve area and ejection fraction in women (p<0.05). In contrast, men had larger left ventricular outflow tract and aortic dimensions but lower incidence of associated trace-mild aortic valve regurgitation (p<0.05). There was a higher incidence of balloon sheath usage in men (men 21.05% vs. women 9.15%, p<0.05) and lower of perclose device (men 19.3% vs. women 31.6%, p<0.05). Postoperatively, the creatinine level and the indexed effective orifice area were higher in men (p<0.05). Conclusion: This study reports that although women had a lower Euro Score II, in-hospital outcomes were similar to men in Italian population.

Ventricular outflow tract

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Mitral Arcades Unexpectedly Encountered During Cardiac Surgery

Journal of Cardiothoracic and Vascular Anesthesia (2020)

Aleksander Dokollari Matteo Cameli Gianluigi Bisleri Mohammad Bin Pervez Didar‐Karan Kalra

10.1053/j.jvca.2020.10.018

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Learning curve predictors for minimally invasive mitral valve surgery; how far should the rabbit hole go?

Journal of Cardiac Surgery (2020)

Aleksander Dokollari Matteo Cameli Didar‐Karan Kalra Mohammad Bin Pervez Michael Demosthenous

Objective To analyze predictors that influence the learning curve of minimally invasive mitral valve surgery (MIMVS). Methods Patients who underwent MIMVS between March 2010 to March 2015 were retrospectively analyzed. Predictive factors that influence the learning curve were analyzed. Results One hundred and five patients were included in the analysis. Cardiopulmonary bypass (CPB) time in minutes was 158.72 ± 40.98 and the aortic cross-clamp (ACC) time in minutes was 114.48 ± 27.29. There were three operative mortalities, one stroke and five >2+ mitral regurgitation. ACC time in minutes was higher in the low logistic Euroscore II (LES) group (LES < 5% = 118.42 ± 27.94) versus (LES ≥ 5 = 88.66 ± 22.26), P < .05 while creatinine clearance in μmol/L was higher in the LES < 5% group (LES < 5% = 84.32 ± 33.7) versus (LES ≥ 5% = 41.66 ± 17.14), (P < .05). One patient from each group required chest tube insertion for pleural effusion P < .05. The cumulative sum analysis (CUSUM) for the first 25 patients had CPB and ACC times that reached the upper limits. Between 25 to 64 patients the curve remained stable while with the introduction of reoperations and complex surgical procedures the CUSUM reached the upper limits. Conclusions The learning curve is affected by many factors but this should not desist surgeons from approaching this technique. The introduction of high-risk patients in clinical practice should be carefully measured based on surgeon experience.

CUSUM

Aortic cross-clamp

Chest tube

10.1111/jocs.14939

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Early and Midterm Clinical Outcomes of Transcatheter Valve-in-Valve Implantation Versus Redo Surgical Aortic Valve Replacement for Aortic Bioprosthetic Valve Degeneration: Two Faces of the Same Medal

Journal of Cardiothoracic and Vascular Anesthesia (2021)

Aleksander Dokollari Matteo Cameli Giulia Elena Mandoli Didar‐Karan Kalra Robert Poston

To compare early and midterm outcomes of transcatheter valve-in-valve implantation (ViV-TAVI) and redo surgical aortic valve replacement (re-SAVR) for aortic bioprosthetic valve degeneration.Patients who underwent ViV-TAVI and re-SAVR for aortic bioprosthetic valve degeneration between January 2010 and October 2018 were retrospectively analyzed. Mean follow-up was 3.0 years.In-hospital, early, and mid-term outcomes.Eighty-eight patients were included in the analysis.Thirty-one patients (37.3%) had ViV-TAVI, and 57 patients (62.7%) had re-SAVR.In the ViV-TAVI group, patients were older (79.1 ± 7.4 v 67.2 ± 14.1, p < 0.01). The total operative time, intubation time, intensive care unit length of stay, total hospital length of stay, inotropes infusion, intubation >24 hours, total amount of chest tube losses, red blood cell transfusions, plasma transfusions, and reoperation for bleeding were significantly higher in the re-SAVR cohort (p < 0.01). There was no difference regarding in-hospital permanent pacemaker implantation (ViV-TAVI = 3.2% v re-SAVR = 8.8%, p = 0.27), patient-prosthesis mismatch (ViV-TAVI = 12 patients [mean 0.53 ± 0.07] and re-SAVR = ten patients [mean 0.56 ± 0.08], p = 0.4), stroke (ViV-TAVI = 3.2% v re-SAVR = 7%, p = 0.43), acute kidney injury (ViV-TAVI = 9.7% v re-SAVR = 15.8%, p = 0.1), and all-cause infections (ViV-TAVI = 0% v re-SAVR = 8.8%, p = 0.02), between the two groups. In-hospital mortality was 0% and 7% for ViV-TAVI and re-SAVR, respectively (p = 0.08). At three-years' follow-up, the incidence of pacemaker implantation was higher in the re-SAVR group (ViV-TAVI = 0 v re-SAVR = 13.4%, p < 0.01). There were no differences in reintervention (ViV-TAVI = 3.8% v re-SAVR = 0%, p = 0.32) and survival (ViV-TAVI = 83.9% v re-SAVR = 93%, p = 0.10) between the two cohorts.ViV-TAVI is a safe, feasible, and reliable procedure.

Stroke

10.1053/j.jvca.2021.05.029

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Citations (16)