Namala Mkopi

Muhimbili National Hospital

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Karim Manji

Muhimbili University of Health and Allied Sciences

Josephine Shabani

Ifakara Health Institute

Harriet Ruysen

London School of Hygiene & Tropical Medicine

Qazi Sadeq-ur Rahman

International Centre for Diarrhoeal Disease Research

Joy E. Lawn

London School of Hygiene & Tropical Medicine

Shafiqul Ameen

International Centre for Diarrhoeal Disease Research

Sojib Bin Zaman

James Madison University

Nahya Salim

Muhimbili University of Health and Allied Sciences

Ahmed Ehsanur Rahman

University of Edinburgh

Louise T. Day

London School of Hygiene & Tropical Medicine

Cooperative Institutions

Muhimbili University of Health and Allied Sciences

Muhimbili National Hospital

London School of Hygiene & Tropical Medicine

Ifakara Health Institute

International Centre for Diarrhoeal Disease Research

Ministry of Health and Population

Nepal Development Research Institute

Stanford University

Johns Hopkins University

Pokhara University

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Evaluating the implementation of the Pediatric Acute Care Education (PACE) program in northwestern Tanzania: a mixed-methods study guided by normalization process theory

BMC Health Services Research (2024)

Joseph R. Mwanga Adolfine Hokororo Hanston Ndosi Theopista Masenge Florence Salvatory Kalabamu

Pace

Health administration

10.1186/s12913-024-11554-3

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Kangaroo mother care: EN-BIRTH multi-country validation study

BMC Pregnancy and Childbirth (2021)

Nahya Salim Josephine Shabani Kimberly Peven Qazi Sadeq-ur Rahman Ashish KC

Kangaroo mother care (KMC) reduces mortality among stable neonates ≤2000 g. Lack of data tracking coverage and quality of KMC in both surveys and routine information systems impedes scale-up. This paper evaluates KMC measurement as part of the Every Newborn Birth Indicators Research Tracking in Hospitals (EN-BIRTH) study.

10.1186/s12884-020-03423-8

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Citations (29)

Additional file 8 of Kangaroo mother care: EN-BIRTH multi-country validation study

Figshare (2021)

Nahya Salim Josephine Shabani Kimberly Peven Qazi Sadeq-ur Rahman Ashish KC

Additional file 8. Markers for quality of KMC by hospital, EN-BIRTH study ≤2000 g, n = 815 observed.

Kangaroo care

10.6084/m9.figshare.14313899

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Prolonged pediatric intensive care unit (PICU) admission, challenges in diagnosis and treatment in a child with hyper IgM syndrome in a tertiary hospital in Tanzania: a case report

Pan African Medical Journal (2024)

Aika Shoo Evance Godfrey Deogratius Mally Yasser Habresh Said Mary DeAlmeida

Hyper immunoglobulin M (IgM) syndromes are a collection of uncommon primary combined immunodeficiency disorders. They are characterized by recurrent bacterial infections due to low levels of IgG, IgA, and IgE, while IgM levels remain normal or high. These conditions stem from a mutation in the CD40 ligand gene or disruptions in the CD40-signaling pathway. Those affected face increased susceptibility to frequent bacterial infections, an elevated likelihood of autoimmune issues, and early-onset malignancies. These syndromes are rare and account for a small fraction of immunodeficiency cases. We describe a case of an African infant, who had a prolonged pediatric intensive care unit admission due to recurrent and severe infections which took a prolonged course of medication to be treated. After a diagnostic workup, a diagnosis of X-linked hyper IgM syndrome was established, and currently, our child is on monthly replacement of IV immunoglobulin and daily prophylactic cotrimoxazole tablets. Early diagnosis of primary immunodeficiency disorders reduces the incidence of infections and the severity of complications. This case demonstrates the consequences of delayed diagnosis and resulting in a prolonged hospital stay.

Tertiary care

Pediatric hospital

10.11604/pamj.2024.49.33.42418

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Additional file 3 of Kangaroo mother care: EN-BIRTH multi-country validation study

Figshare (2021)

Nahya Salim Josephine Shabani Kimberly Peven Qazi Sadeq-ur Rahman Ashish KC

Additional file 3. Background characteristics of women observed in KMC ward, EN-BIRTH study.

Kangaroo care

Paternal care

10.6084/m9.figshare.14313884

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Additional file 9 of Kangaroo mother care: EN-BIRTH multi-country validation study

Figshare (2021)

Nahya Salim Josephine Shabani Kimberly Peven Qazi Sadeq-ur Rahman Ashish KC

Additional file 9. Markers for quality of KMC by hospital, EN-BIRTH study all weights, n = 840 observed.

10.6084/m9.figshare.14313902

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EN-BIRTH Data Collector Training - Supporting Annexes

Louise T. Day Harriet Ruysen Vladimir Sergeevich Gordeev Georgia R. Gore‐Langton Dorothy Boggs

The EN-BIRTH study aims to validate selected newborn and maternal indicators for routine facility-based tracking of coverage and quality of care for use at district, national and global levels. The item contains consent forms and participant information, in addition to standard operating procedures (SOP) for adverse clinical events, and managing distress in interviews. The full complement of annex files used during the training can be requested via this site if required.

Standard operating procedure

Complement

10.17037/data.00000953

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High Nasal Carriage of Methicillin-ResistantStaphylococcus aureusAmong Healthy Tanzanian Under-5 Children

Microbial Drug Resistance (2013)

Sabrina J. Moyo Said Aboud Bjørn Blomberg Namala Mkopi Mabula Kasubi

This study aimed to determine the prevalence of Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) carriage, risk factors of colonization and antimicrobial susceptibility patterns of S. aureus strains. The study was conducted at the Muhimbili National Hospital in Dar es Salaam, Tanzania. Nasal swabs were obtained from children and S. aureus was isolated and identified using conventional culture methods. MRSA was screened and confirmed using the cefoxitin disk and multiplex real-time polymerase chain reaction, respectively. Antibiotic susceptibility was performed using the Kirby-Bauer disk diffusion method. MRSA isolates were further characterized by pulsed field gel electrophoresis (PFGE) profiling. Of 285 children included in the study, S. aureus was detected in 114 (40%). Of the 114 isolates, 12 (10.5%) were MRSA. PFGE results showed that these MRSA isolates are epidemiologically unrelated. Resistance of all S. aureus to trimethoprim-sulfamethoxazole, tetracycline, gentamicin, and ciprofloxacin was 65.8%, 23.7%, 27.2%, and 4.4%, respectively. No resistance to vancomycin was found. The prevalence of inducible clindamycin resistance, constitutive clindamycin resistance, MS phenotype (resistance to erythromycin alone), and multidrug resistance was 16.7%, 1.8%, 14.0%, and 16.8%, respectively. None of the risk factors examined was found to be significant. This is the first report of S. aureus and nasal carriage of MRSA and a high rate of S. aureus carriage was found in Tanzanian under-5 children. The study findings support the need for proper health education and effective infection control measures for healthcare workers.

Anterior nares

Mupirocin

Trimethoprim

Carriage

Sulfamethoxazole

Fusidic acid

10.1089/mdr.2013.0016

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EN-BIRTH Data Collection Tools

Louise T. Day Harriet Ruysen Vladimir Sergeevich Gordeev Georgia R. Gore‐Langton Dorothy Boggs

The EN-BIRTH study aims to validate selected newborn and maternal indicators for routine facility-based tracking of coverage and quality of care for use at district, national and global levels. The item contains the following data collection tools: Register data extraction, Observation checklist (labour and delivery ward), Observation checklist (kangaroo mother care), Patient record verification tools for antenatal corticosteroid administration, Patient record verification tools for antibiotic administration, and the Maternal recall survey.

Data extraction

Tracking (education)

10.17037/data.00000951

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Citations (1)

Evaluating the Implementation of the Pediatric Acute Care Education (PACE) Program in Northwestern Tanzania: A Mixed-Methods Study Guided by Normalization Process Theory

Research Square (Research Square) (2024)

Joseph R. Mwanga Adolfine Hokororo Hanston Ndosi Theopista Masenge Florence Salvatory Kalabamu

Abstract Background In low- and -middle-income countries (LMICs) like Tanzania, the competency of healthcare providers critically influences the quality of pediatric care. To address this, we introduced PACE (Pediatric Acute Care Education), an adaptive e-learning program tailored to enhance provider competency in line with Tanzania’s national guidelines for managing seriously ill children. Adaptive e-learning presents a promising alternative to traditional in-service education, yet optimal strategies for its implementation in LMIC settings remain to be fully elucidated. Objectives This study aimed to (1) evaluate the initial implementation of PACE in Mwanza, Tanzania, using the constructs of Normalization Process Theory (NPT), and (2) provide insights into its feasibility, acceptability, and scalability potential. Methods A mixed-methods approach was employed across three healthcare settings in Mwanza: a zonal hospital and two health centers. NPT was utilized to navigate the complexities of implementing PACE. Data collection involved a customized NoMAD survey, focus groups and in-depth interviews with healthcare providers. Results The study engaged 82 healthcare providers through the NoMAD survey and 79 in focus groups and interviews. Findings indicated high levels of coherence and cognitive participation, demonstrating that PACE is well-understood and resonates with existing healthcare goals. Providers expressed a willingness to integrate PACE into their practice, distinguishing it from existing educational methods. However, challenges related to resources and infrastructure, particularly affecting collective action, were noted. The short duration of the study limited the assessment of reflexive monitoring, though early indicators point towards the potential for PACE’s long-term sustainability. Conclusion This study offers vital insights into the feasibility and acceptability of implementing PACE in a Tanzanian context. While PACE aligns well with healthcare objectives, addressing resource and infrastructure challenges is crucial for its successful and sustainable implementation. Furthermore, the study underscores the value of NPT as a framework in guiding implementation processes, with broader implications for implementation science and pediatric acute care in LMICs.

Pace

10.21203/rs.3.rs-4432440/v1

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