Arjan Bel

University of Amsterdam

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Co-Authors

Tanja Alderliesten

Leiden University Medical Center

N. Van Wieringen

University of Amsterdam

Maarten C.C.M. Hulshof

University of Amsterdam

J. Visser

University of Arusha

C. Rasch

Leiden University Medical Center

Bradley R. Pieters

University of Amsterdam

Astrid van der Horst

University of Amsterdam

Z. van Kesteren

University of Amsterdam

Peter A. N. Bosman

Centrum Wiskunde & Informatica

Geertjan van Tienhoven

University of Amsterdam

Cooperative Institutions

University of Amsterdam

204

Academic Medical Center

173

Amsterdam University Medical Centers

168

Medical Cañada (Spain)

117

The Netherlands Cancer Institute

University Medical Center Utrecht

Cancer Center Amsterdam

Utrecht University

Heidelberg University

Vrije Universiteit Amsterdam

Author Statistics

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Research Field

PO-1735 A systematic review on motion, margins and delineation variability in thoraco-abdominal pediatric RT

Radiotherapy and Oncology (2021)

KA Meijer I. Van Dijk Sophie C. Huijskens Joost G. Daams C. Windmeijer

10.1016/s0167-8140(21)08186-x

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Technical and Clinical Evaluation of the ALBA-4D 70MHz Loco-Regional Hyperthermia System

Remko Zweije H. Petra Kok A. Bakker Arjan Bel Johannes Crezee

Hyperthermia, increasing tumor temperatures to 39-43°C for 1 h, enhances the effectiveness of radiotherapy and chemotherapy. Deep seated pelvic tumors are usually heated by arrays of radiofrequency or microwave antennas placed around the patient, capable of focussing power onto the tumor. The AMC developed the AMC 4 loco-regional hyperthermia system with 4 rectangular 70 MHz waveguide antennas for heating deep-seated pelvic tumors. This system has been commercialized as the ALBA4D utilizing the same geometric layout and the same waveguides. Goal of this study was to evaluate the performance of the ALBA4D system. We compared electric field (E-field) distributions in a patient-mimicking phantom and confirmed that phase control of the focal point is similar to the AMC 4, thus ensuring similar clinical performance.

Electromagnetic heating

Microwave heating

10.23919/eumc.2018.8541673

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Citations (20)

OC-0282: Considerable intra-breath-hold motion and inter-breathhold position variation of pancreatic tumors

Radiotherapy and Oncology (2015)

E. Lens Astrid van der Horst Eva Versteijne Geertjan van Tienhoven Arjan Bel

Position (finance)

Variation (astronomy)

10.1016/s0167-8140(15)40280-4

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Citations (1)

[Guanine deaminase or guanase, the enzyme of hepatic cytolysis. Its diagnostic value in 500 patients].

PubMed (1970)

Arjan Bel R Dietsch Robert Alary B Savoye R Levrat

Value (mathematics)

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Citations (2)

A verification procedure to improve patient set-up accuracy using portal images

Radiotherapy and Oncology (1993)

Arjan Bel Marcel van Herk Harry Bartelink Joos V. Lebesque

10.1016/0167-8140(93)90255-7

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Citations (261)

[Experimental gastric ulcer induced by serotonin in rats. Its development and prevention].

PubMed (1966)

Arjan Bel R Levrat J Nesmoz M Girard

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Citations (0)

Electronic Portal Imaging

Definitions (2020)

Marcel van Herk Arjan Bel Kenneth G. A. Gilhuijs Joos V. Lebesque A. Van Dalen

In our institute, we have developed an electronic portal imaging system based on a matrix of 256 x 256 ionisation chambers. By improvements to the electronics, the system produces images with the same quality as the original system but 3-10 times faster. Software for automatic image analysis has been applied to more than 10,000 images over the last two years. Using an off-line correction strategy, the systematic patient set-up error has been limited to 5 mm or less for 98% of the patients treated for prostate cancer.

Electronic systems

10.32388/1foxaf

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Citations (5)

Feasibility of Conebeam CT-based Online Adaptive Radiotherapy for Neoadjuvant Treatment of Rectal Cancer.

Research Square (Research Square) (2021)

Rianne de Jong J. Visser N. Van Wieringen Jan Wiersma Debby Geijsen

Abstract Background Online adaptive radiotherapy has the potential to reduce toxicity for patients treated for rectal cancer because smaller planning target volumes (PTV) margins around the entire clinical target volume (CTV) are required. The aim of this study is to describe the first clinical experience of a Conebeam CT(CBCT)-based online adaptive workflow, evaluating timing of different steps in the workflow, plan quality, target coverage and patient compliance. Methods Twelve consecutive patients eligible for 5 x 5 Gy pre-operative radiotherapy were treated on a ring-based linear accelerator with a multidisciplinary team present at the treatment machine for each fraction. The accelerator is operated using an integrated software platform for both treatment planning and delivery. In all directions for all CTVs a PTV margin of 5 mm was used, except for the cranial/caudal borders of the total CTV where a margin of 8mm was applied. A reference plan was generated based on a single planning CT. After aligning the patient the online adaptive procedure started with acquisition of a CBCT. The planning CT scan was registered to the CBCT using deformable registration and a synthetic CT scan was generated. With the support of artificial intelligence, structure guided deformation and the synthetic CT scan contours were adapted by the system to match the anatomy on the CBCT. If necessary, these contours were adjusted before a new plan was generated. A second and third CBCT were acquired to validate the new plan with respect to CTV coverage just before and after treatment delivery, respectively. Treatment was delivered using volumetric modulated arc treatment (VMAT). All steps in this process defined and timed. Results On average the timeslot needed at the treatment machine was 34 minutes. The process of acquiring a CBCT, evaluating and adjusting the contours, creating the new plan and verifying the CTV on the CBCT scan took on average 20 minutes. Including delivery and post treatment verification this was 26 minutes. Manual adjustments of the target volumes were necessary in 50% of fractions. Plan quality, target coverage and patient compliance were excellent. Conclusions First clinical experience with CBCT-based online adaptive radiotherapy shows it is feasible for rectal cancer. Trial registration Medical Research Involving Human Subjects Act (WMO) does not apply to this study and was retrospectively approved by the Medical Ethics review Committee of the Academic Medical Center (W21_087 # 21.097; Amsterdam University Medical Centers, Location Academic Medical Center, Amsterdam, The Netherlands).

Margin (machine learning)

10.21203/rs.3.rs-292967/v1

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Citations (8)

Fer non lié à la transferrine chez quatre patients hypersidérémiques.

La Nouvelle presse médicale (1982)

M Vernet-Nyssen S Abramian Denis Girard Arjan Bel

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OC-0174: Deformable image registration for dose accumulation of adaptive EBRT and BT in cervical cancer

Radiotherapy and Oncology (2018)

Laura E van Heerden J. Visser C. Koedooder C. Rasch Bradley R. Pieters

Image registration

10.1016/s0167-8140(18)30484-5

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Citations (0)