Heri Wijaya

Universitas 17 Agustus 1945 Samarinda

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Co-Authors

Siti Jubaidah

Universitas 17 Agustus 1945 Samarinda

Hayatus Sa’adah

Universitas 17 Agustus 1945 Samarinda

Eka Siswanto Syamsul

Universitas 17 Agustus 1945 Samarinda

Sandeep Poddar

Lincoln University College

Supomo Supomo

Universitas Gadjah Mada

Rusdiati Helmidanora

Universitas 17 Agustus 1945 Samarinda

Widya Astuty Lolo

Sam Ratulangi University

Yulistia Budianti Soemarie

Universitas Islam Kalimantan Muhammad Arsyad Al Banjary

Gayatri Citraningtyas

Sam Ratulangi University

Henny Nurhasnawati

Universitas 17 Agustus 1945 Samarinda

Cooperative Institutions

Universitas 17 Agustus 1945 Samarinda

Universitas Gadjah Mada

Sam Ratulangi University

Lincoln University College

Politeknik Kesehatan Kemenkes Semarang

Ministry of Health

Universitas Muhammadiyah Kupang

IPB University

Universitas Wijayakusuma Purwokerto

Institut Sains dan Teknologi Terpadu Surabaya

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The Potential of Lai Fruit Seed Starch (Durio kutejensis) as A New Excipient in Pharmaceutical Preparations Through Specific and Non-Specific Characterization

International Journal of Advancement in Life Sciences Research (2022)

Hayatus Sa’adah Heri Wijaya Rosiana Ramadhana Yulistia Budianti Soemarie

Backgorund: Lai fruit seeds (Durio kutejensis) contain starch. In the pharmaceutical field, starch can be used as an ingredient in the formulation of tablet preparations such as fillers, binders, and disintegrants. Objective: This research is to determine the Potential of Lai Fruit Seed Starch (Durio Kutejensis) as A New Excipient in Pharmaceutical Preparations. Methods: The research process started from plant determination, sample collection, starch manufacture, and examination of specific and non-specific characteristics as well as testing the starch content of other fruit seeds. Result: The content of the extract is 12.5% water soluble, and the content of the extract is soluble in ethanol 1.5%. Based on the non-specific parameters of lai fruit seed starch, the water content was 11.4%, the ash content was 1.5%, and the acid insoluble ash content was 0.75%. The starch content test of lai fruit seeds was found to contain fructose. Conclusion: the seed starch of lai fruit has the potential to be used as an alternative to new excipients in pharmaceutical preparations.

Excipient

Ingredient

10.31632/ijalsr.2022.v05i03.005

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Antioxidant Activity Test of Red Pidada Leaves (Sonneratia caseolaris L.) using ABTS Method (2,2-azinobis-(3-ethylbenzothiazolin)-6-sulfonicacid)

Research Journal of Pharmacy and Technology (2022)

Eka Siswanto Syamsul Supomo Supomo Siti Jubaidah Heri Wijaya Dwi Lestari

The Red Pidada (Sonneratia caseolaris L.) is one of the plants used in traditional ways, especially by Borneo's people, where the red Pidada leaves are used as a cool powder composition and applied to the face while doing activities under exposure to sunlight over a long time. Red Pidada extract has a very strong antioxidant activity of 21.62 ppm because it has secondary metabolite, which is a medicinal ingredients and have a strong molecular structure, and have various biological activities. Pidada redplant (Sonneratia caseolaris L.) is a mangrove that has antioxidant potential. Free radicals can cause cancer, heart disease, premature aging, and other degenerative diseases. The research objective was to determine the antioxidant activity of the Pidada red leaf extract and fraction.The research was conducted qualitatively and quantitatively. The qualitative test was carried out by the colour change test and the quantitative test using the ABTS method (2,2-azinobis-3-ethyl benzothiazolin-6-sulfonic acid) with a UV-Visspectrophotometer. Pidada redleaves were extracted and fractionated, namely ethanol extract, n-hexane fraction, ethyl acetate fraction, and ethanol fraction, and made inti various concentrations compared to vitamin C.The IC50 value determined the antioxidant activity. The results showed that the ethanol extract had an IC50 value of 1.32 ppm (very strong), n-hexanefraction of 19.89 ppm (very strong), ethylacetate fraction of 0.50 ppm (very strong), and ethanolfraction of 1.63 ppm (very strong).

ABTS

Fraction (chemistry)

10.52711/0974-360x.2022.00663

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Citations (5)

Ethanol Extract Dry Syrup Granulation Formulation Dayak Onion Bulb (Eleutherine bulbosa (Mill.) Urb.)

International Journal of Advancement in Life Sciences Research (2024)

Yullia Sukawaty Hayatus Sa’adah Heri Wijaya G. T. Austin

Background: Dayak onion (Eleutherine bulbosa (Mill.) Urb.) is one kind of medicinal plant native to East Kalimantan that has antioxidant activity. The dosage form that can be developed is dry syrup granules which become one of the most simple dosage forms in preparation, easy to use, storage-stable and can cover the bitter taste of the drug. The goal of this study was to find the best mix of Avicel PH 101 and Na CMC to make dry syrup granules that meet the requirements for physical properties. Methods: Research was carried out experimentally using three formulas with combinations of Avicel PH 101 and Na-CMC. The ratios of Avicel PH 101 and Na-CMC were (1:0); (0.5:0.5) and (0:1). The evaluation of dry syrup granules included organoleptic observations, a moisture content test, a flowability test, a reconstitution time test, pH test, viscosity test and a hygroscopic test. Result: dry syrup granules with variation 1:0 of Avicel PH 101 and Na-CMC have the best requirements for physical properties, i.e. moisture content of 2.47%, the flow time of 0.91 seconds, an angle of repose 25.19 ° and tap index of 10.67%. Conclusion: Dry syrup granules with a ratio of Avicel PH 101 and Na CMC (1:0) are preparations that best meet the physical properties requirements, namely moisture content of 2.47%, flow time of 0.91 seconds, angle of repose 25, 19° and a fixing index of 10.67%.

Bulb

Granulation

10.31632/ijalsr.2024.v07i01.011

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Perbandingan Metode Esktraksi Terhadap Rendemen Ekstrak Batang Turi (Sesbania Grandiflora L.) Dengan Menggunakan Metode Maserasi Dan Sokhletasi

Indonesian Journal of Pharmacy and Natural Product (2022)

Heri Wijaya Siti Jubaidah Rukayyah Rukayyah

ABSTRAKBatang turi (Sesbania grandiflora L) merupakan bagian tumbuhan yang dapat digunakan sebagai obat kumur dan mengandung zat saponin, flavonoid, polifenol, dan tanin. Senyawa dari tumbuhan dapat diperoleh dengan cara ekstraksi. Rendemen rendemen ekstrak dalam proses ekstraksi dapat dipengaruhi oleh beberapa faktor, seperti metode ekstraksi, waktu ekstraksi. Tujuan dari penelitian ini adalah untuk mengetahui rendemen rendemen ekstrak batang turi menggunakan metode maserasi dan sokletasi. Penelitian yang dilakukan adalah penelitian eksperimen. Tahapan penelitian meliputi pengambilan sampel, penentuan tanaman, pengolahan sampel, proses ekstraksi maserasi dan sokletasi, perhitungan rendemen rendemen, penentuan kadar air, penapisan fitokimia. Hasil penelitian menunjukkan bahwa metode sokletasi menghasilkan rata-rata nilai rendemen rendemen yang lebih tinggi yaitu sebesar 7,76% dan rendemen hasil maserasi dengan nilai rendemen rata-rata sebesar 6,13%. Skrining fitokimia batang turi menunjukkan hasil positif.Â

10.35473/ijpnp.v5i1.1469

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Citations (5)

Formulation of Edible Film Ethanol Extract of Kaffir Lime (Citrus hystrix) Leaves Using Corn Starter and Cassava Starter Variations

International Journal of Advancement in Life Sciences Research (2022)

Hayatus Sa’adah Heri Wijaya Ria Novita Sari

Introduction: Kaffir lime leaves are plants that have antibacterial activity against Streptococcus mutans. Streptococcus mutans bacteria are bacteria located in the oral cavity and can cause dental caries disease. Objective: This research will develop edible film preparation of the extract of kaffir lime leaves ethanol using cassava starch and corn starch as gelling material. Methods: Edible film of kaffir lime leaf extracts is then evaluated for physical properties that include fragility, shrinkage drying, pH and thickness. The data obtained were analyzed by qualitative and quantitative analysis. Result: Kaffir lime leaf extract with 25% extract concentration showed that its physical properties qualified physical properties in accordance with comparative products, but for pH test only formula with the use of cassava starch as a hydrocolloid binder that meets the pH of mouth. Conclusion: Panelists prefer an edible film with cassava starch composition as a hydrocolloid former.

Starter

10.31632/ijalsr.2022.v05i02.003

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Citations (2)

PENETAPAN KADAR FLAVONOID EKSTRAK TERPURIFIKASI UMBI BAWANG DAYAK (Eleutherine palmifolia (L). Merr) SECARA SPEKTROFOTOMETRI

Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan (2019)

Siti Jubaidah Eka Siswanto Heri Wijaya Muhammad Putu Aditya

Eleutherine palmifolia (L) Merr. is one of the plant that has function as medicine. One of the compound which much contained in ethanol extract of dayak union is flavonoid, so that could separate with purification. The aim of this study is to determine flavonoid levels in purified extract of dayak union root with various drying treatments using UV-Vis spectrophotometry and to find out which drying treatment that obtaine the highest flavonoid levels.Drying treatment of dayak union root simplicia were with direct sunlight for 6 hours (P1), dried by oven with temperature 60ÂoC for 6 hours (P2), dried by covered with black clothes (P3). Dayak union root simplicia extracted by maceratiin method using ethanol 70%, and purified step by step using n-hexane solvent. Flavonoid levels test of purified extract of dayak union root carried outby UV-Vis spectrophotometry method.The results of UV-Vis spectrophotometry obtained flavonoid levels of purified extract of dayak union root in dried by direct sunlight (P1) was 0.79%, dried by oven with temperature 60ÂoC (P2) was 1.57%, and dried by coveredwith black clothes (P3) was 1.02%. LSD test shows (P<0.05) the significant differences between flavonoid levels with different drying treatment.

10.36387/jiis.v4i1.225

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Citations (3)

PKM Buah Naga Merah Di Kecamatan Samboja Kabupaten Kutai Kartanegara Provinsi Kalimantan Timur

Jurnal Abdimas Mahakam (2018)

Heri Wijaya Yulistia Budianti Soemarie Nurul Fatimah

Pelatihan ini dilaksanakan dalam rangka Program Kemitraan Masyarakat, dengan sasaran adalah masyarakat Kecamatan Samboja khususnya warga Desa Wonotirto dan Desa Beringin agung. Pelatihan dilakukan dalam lima (5) tahap. Metode pelatihan budidaya ini dengan melakukan pelatihan dan penyuluhan kepada peserta tentang budidaya tanaman buah naga merah, penanganan virus dan penanganan paska panen, proses pembuatan sirup dan ice cream dari daging buah naga merah, proses pengolahan saos dan saos pedas dari limbah kulit buah naga merah, Proses pengemasan produk olahan, dan cara analisis ekonomi dan strategi pemasaran.Peserta dibagi menjadi 2 kelompok. Kelompok pertama adalah petani buah naga dan kelompok kedua adalah ibu-ibu PKK. Kegiatan pertama dilakukan dengan mengundang narasumber dari Dinas Tanaman Pangan dan Hortikultura.Penyampaian materi dengan metode ceramah dilakukan di dalam ruangan yang dilanjutkan dengan diskusi dan praktek yang dilakukan langsung oleh peserta pelatihan dengan dibimbing oleh pemateri

10.24903/jam.v2i2.375

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Quality of Life of Hypertensive Patients Undergoing Chronic Disease Management Program during the COVID-19 Pandemic

Kesmas National Public Health Journal (2022)

Widya Astuty Lolo Gayatri Citraningtyas Deby A. Mpila Heri Wijaya Sandeep Poddar

The COVID-19 pandemic has restricted some common activities for hypertensive patients undergoing the Chronic Disease Management Program/Program Pengelolaan Penyakit Kronis in primary health care, decreasing the quality of life. This study aimed to measure the quality of life of hypertensive patients undergoing the Chronic Disease Management Program at primary health care of Manado City, North Sulawesi Province, Indonesia, during the COVID-19 pandemic and determine the factors influencing hypertension such as sex, age, education, employment status, monthly income and duration of hypertension. This cross-sectional study was carried out on 150 hypertensive patients randomly sampled at primary health care from June to September 2021. The data were analyzed using the Mann-Whitney test. The quality of life of non-complicated hypertensive patients was higher than those with complications. The utility value and the visual analog scale of hypertensive patients with and without complications were 0.808±0.13 and 80.2±8.16 and 0.761±0.17 and 75.1±7.56, respectively. The results showed that most hypertensive patients, with or without complications, had a good quality of life.

Pandemic

10.21109/kesmas.v17i4.6224

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Citations (5)

Jurnal Ilmiah Manuntung (2018)

Heri Wijaya Novitasari Novitasari Siti Jubaidah

10.51352/jim.v4i1.148

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Citations (21)

Jurnal Ilmiah Manuntung (2018)

Siti Jubaidah Ria Indriyani Hayatus Sa’adah Heri Wijaya

10.51352/jim.v4i1.146

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Citations (0)