Jianping Gao

Xi'an Jiaotong University

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Research Trends

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Co-Authors

Zhengyu Zhang

Zhongnan Hospital of Wuhan University

Jingping Ge

Nanjing University

Kong-Han Pan

Sir Run Run Shaw Hospital

Fei Ma

Xi'an Jiaotong University

Hongqing Ma

Hebei Medical University

Guanghong Ding

Fudan University

Yuanjiang Lv

Xi'an Jiaotong University

Wenqian Sun

Xi'an Jiaotong University

Ling Zhao

Sichuan Agricultural University

Wenquan Zhou

Nanjing University

Cooperative Institutions

Zhejiang University

Chinese Academy of Medical Sciences & Peking Union Medical College

Chinese Academy of Sciences

Sir Run Run Shaw Hospital

Xi'an Jiaotong University

Fudan University

Shanghai Jiao Tong University

Peking Union Medical College Hospital

Sun Yat-sen University

Nanjing Medical University

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[Effect of Chrysanthemum indicum on ventricular remodeling in rats].

Zhongyaocai (2010)

Qi Wu Chen Chang-xun Wei-Liang Gu Jianping Gao Yin Wan

To explore the effects and mechanism of Chrysanthemum indicum on experimental ventricular remodeling induced by isoprenaline (ISO) and L-thyroxine (L-Thy).The ventricular remodeling of mice were induced by subcutaneous injection of ISO with the dosage of 2 mg/kg daily for 7 d and the rats with L-Thy intraperitoneally with the dosage of 0.25 mg/kg daily for 9 d. After 7 days' treatment, the cardiac index and the Ang II content in myocardium of mice were measured. After 9 days' treatment, the ratios of LVW/BW, HW/BW of rats were calculated, the Ang II content in heart tissue and the ALD, TNF-alpha concentration in serun were determined by radioimmunoassay, the Hydroxy proline (Hyp) content in heart tissue were measured by hydrolysis method.After 7 - 9 days of treatment, Chrysanthemum indicum significantly reduced the left ventricular weight index and heart weight index in mice and rats with myocardial hypertrophy, decreased the content of Ang II in ventricular tissue in mice and rats, and reduced the ALD, TNF-alpha concentration in serum and the Hyp content in ventricular tissue in rats (P < 0.05).Chrysanthemum indicum can significantly attenuate the experimental ventricular remodeling; the mechanism may be related with restricting the activity of the sympathetic nervous system and decreasing the levels of Ang II, ALD and TNF-alpha.

Isoprenaline

Ventricular hypertrophy

Subcutaneous injection

Ventricular remodeling

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Clinical observation of Fangfengtongsheng powder in treating sixty patients with cholinergic urticaria

Hebei Journal of Traditional Chinese Medicine (2001)

Jianping Gao

Objective To observe the therapeutic effect of Fangfengtongsheng powder on cholinergic urticaria.Methods In treatment group(n=60) Fangfengtongsheng powder was decocted in water for oral administration,one dose daily,taken twice per day(morning and evening);in control group(n=50) teldane 60mg was orally taken twice a day,cimitidine 25mg and cinnarizine 25mg were orally taken three times per day,with a treatment course of 10 days for both groups.The therapeutic effect was evaluated after three courses.Results The total effective rate was 91.76% in treatment group and 74.0% in control group, there was significant difference between two groups( P 0. 05) . Conclusion Fangfengtongsheng powder is effective in treating cholinergic urticaria.

Therapeutic effect

Cinnarizine

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[Induction of prostate cancer-specific CTLs with dendritic cells pulsed by different types of tumor antigens].

PubMed (2010)

Song Xue Ying-hao SUN Jianping Gao Xiaofeng Xu Zhengyu Zhang

To study the effectiveness of freeze-thaw antigens and acid eluted peptide antigens extracted from tumor cell-pulsed dendritic cells (DC) in inducing prostate cancer-specific cytotoxic T lymphocytes (CTL) in vitro.Tumor antigens were extracted from the prostate cancer cell line PC-3 with the repeated freeze-thaw and weak acid elution methods. Peripheral blood mononuclear cells were cultured with recombinant human GM-CSF and IL-4 for inducing DCs in vitro. Then the DCs were pulsed with the two kinds of prostate cancer tumor antigens respectively and cultured with T cells for inducing CTLs. The activity of the tumor-specific CTLs were detected by LDH release assay.The protein content in the tumor antigens obtained from PC-3 (2 x 10(7)) by citric acid-phosphate buffer elution and that by the repeated freeze-thaw method were (212.2 +/- 7.9) microg and (963.0 +/- 25.3) microg, respectively. The two kinds of prostate cancer antigens-pulsed DCs had a significant role in inducing the PC-3 cell-specific CTLs, and the CTLs induced by acid-eluted peptide antigen-pulsed DCs exhibited an even more significant tumor-specific cytotoxicity than those induced by repeated freeze-thaw ([60.4 +/- 5.52]% vs. [43.7 +/- 4.11]%, P < 0.01).Both the weak acid elution and repeated freeze-thaw methods for extracting prostate cancer antigens can be used for in vitro sensitization of DCs. The DCs pulsed by either of the two kinds of antigens can activate CTLs, and the antigens extracted by weak acid elution are even more effective.

CTL*

Tumor Antigen

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Nursing cooperation in the laparoscopic surgery for insulinoma

Zhonghua xiandai huli zazhi (2011)

Jianping Gao Ran Li

Objective To study nursing experience of laparoscopic insulinoma resections.Methods 50 operation processes of laparoscopic insulinoma resection were summarized. Results We got satisfied effects through perioperation nursing management. All operations were smooth and no accidence occurred. Conclusions Laparoscopic resection of pancreatic insulinoma has less damage to patients.Enhancing perioperation management to patients, paying attention to monitor and adjusting blood glucose and preventing occurrence of hypoglycemia coma should be done to ensure operation being carried out safely and smoothly. Key words: Insulin-Secreting cells; Laparoscopy; Nursing; Isulinoma

Nursing management

Coma (optics)

10.3760/cma.j.issn.1674-2907.2011.21.021

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Infection Control and Management in Modern Operative Sterile and Supply Center

Zhongguo yiyuan ganranxue zazhi (2010)

Jianping Gao

OBJECTIVE To explore an effective method to control infection and enhance the quality of nursing care in modern operative sterile and supply center.METHODS The operating room and sterile and supply department were designed and constructed as a union,and form sound monitor organization,rules and regulations system.Besides,the sterilization monitor and quality control were focused on.RESULTS The quality of infection management in operative sterile and supply center was improved.All the measures of infection control were carried out and prevented the intraoperative nosocomial infection.CONCLUSION In operative sterile and supply center,scientific management is a crucial way to control infection.

Sterilization

Asepsis

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A novel strategy to spare adrenal gland in retroperitoneal laparoscopic radical nephrectomy for renal cancer

Journal of laparoscopic surgery (2012)

Jianping Gao

Objective:To review the local anatomy between the kidney and adrenal gland and explore a novel strategy in retroperitoneal laparoscopic radical nephrectomy to spare adrenal gland.Methods:One hundred and five cases with localized renal carcinoma were enrolled in this study,among whom tumors of 48 cases were in the left kidney and 57 cases in the right kidney.The maximum diameter of tumors were 1.5 cm to 7.5 cm with an average of 4.3 cm.All patients underwent retroperitoneal laparoscopic radical nephrectomy sparing adrenal gland according to the novel strategy.After the main kidney vessels were disposed of,the fat and fascia were dissociated to the renal anterior fascia at medial area of renal hilum,inferior to the adrenal gland,then the upper pole of the kidney was raised so that it was tensile,and the bottom of adrenal gland was dissociated from posterior and upper part of kidney to medial and upper part of the upper pole of the kidney.Finally,the adrenal gland was thoroughly dissociated from the perirenal fat after separation from medial side of renal upper pole to medial side of prerenal fascia.Results:All the operations were successful and none was converted to laparotomy.Lateral branch of adrenal glands were slightly dilacerated in 3 cases during the operation.The mean operative time was 43 min(range from 31 to 80 min).The mean intra-operative blood loss was 30 ml(ranges from 10 to 150 ml).All patients were discharged from hospital in 3 to 7 d after surgery.Conclusions:According to this strategy which is based on the retroperitoneal laparoscopic anatomy of kidney and adrenal gland,the operation is more directive with better explosure and less interference from radian of upper pole of kidney and perirenal fat.Slight advance after separation of adrenal gland can completely dissociate the adrenal gland from perirenal fat.This strategy is supposed to make the operation easier and faster,and decrease the opportunity of laceration of the adrenal gland.

Renal hilum

Kidney cancer

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[Research progress in breath analysis for patients with pulmonary infection and respiratory critical diseases].

PubMed (2016)

Jianping Gao Ping Wang Kejing Ying

Pulmonary infection

Breath gas analysis

10.3760/cma.j.issn.1001-0939.2016.03.018

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