69 children suffering from portal hypertension have been analysed. 5 of these patients died following shunt surgery, 2 after palliative surgery and 2 died in a state of haemorrhagic shock before any treatment could be commenced. In all those patients who died following shunt surgery, thrombosis in some part of the portal vein was found at post mortem. This led to partial liver necrosis.

Palliative surgery

Portal vein thrombosis

Haemorrhagic shock

Hemorrhagic shock

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[Bilateral intrauterine torsion of the spermatic cord (case report) (author's transl)].

PubMed (1977)

Zimmermann Fa James C. Engert P Meister

A case of bilateral intrauterine torsion of the spermatic cord is reported. The possibility of an intrauterin origin is given by observations in newborn infants. The head symptoms are scrotal swelling, flush and induration. Already a suspected torsion of the spermatic cord justifies immediate surgery as the germinative and interstitial cells are irreversibly damaged after very short time. The obstetrician is obliged to diagnose these pre- or perinatally originated torsions and to arrange immediate surgery.

Spermatic cord

Spermatic Cord Torsion

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[Reconstruction of the bile ducts in the rat using choledocho-choledochostomy over a lost drain. Studies on an autologous model and orthotopic liver transplantation].

PubMed (1981)

Zimmermann Fa K Obermüller Gokel Jm S Dorn-Kling

Four different techniques for reconstruction of the bile drainage have been employed in an autologous model. Biochemical liver parameters e. g. Bilirubin, AP, GPT and GOT, cholangiography and histology proved the superiority of our method of an intraductal tubus technique (lost drain method). The covering of the bile duct with the mobilised greater omentum seems to be important for a rapid revascularisation. The superiority of our method was proven in orthotopic liver isografting as well.

Orthotopic liver transplantation

Extrahepatic Bile Ducts

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A new approach to duct management in pancreatic transplantation: temporary occlusion with fibrin sealing and enterostomies.

PubMed (1987)

Zimmermann Fa G. Pistorius K. Grabowsky Isabel Marzi Gerhard Seitz

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[Gluconeogenesis in perfused rat liver following preservation in various temperature ranges].

PubMed (1977)

Zimmermann Fa O. Köhler H Feldmeier Roland W. Scholz

Experiments with perfused rat livers have shown that rates of various metabolic processes are influenced by changes in temperature in different ways. Cytosolic processes exhibit a linear temperature dependence when plotted in an Arrhenius-diagram in the range between 37 degrees and 1 degree C. In contrast, processes which are bound to mitochondrial membranes show phase changes at 22 degrees C. Furthermore, with gluconeogenesis another phase was observed at 11 degrees C. After 24 hour of perfusion at 11 degrees C the livers produced more glucose from gluconeogenic precursors when perfused at 37 degrees C than after perfusion at 4 degrees C. The importance of the balance of metabolism during hypothermia is discussed by comparison with metabolism of poikilothermic animals.

Gluconeogenesis

Poikilotherm

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