To identify the estimated fetal weight (EFW) formula and threshold for the optimal prediction of fetal growth restriction (FGR) at 26-34 weeks' in fetuses with gastroschisis.Late second and third trimester ultrasound data were used to calculate the EFW utilizing eight different formulas: Hadlock I-IV, Honarvar, Shepard, Siemer, and Warsof. EFW and birth weight percentiles were assigned from US population growth curves. FGR and small for gestational age (SGA) were defined as EFW and birth weight less than the tenth percentile for gestational age; Receiver operating characteristic (ROC) curves were used to compare formula performance for FGR diagnosis at 26-34 weeks' to identify an SGA birth weight.There were 170 newborns with gastroschisis; 46 (27%) were SGA. The mean gestational age at the time of ultrasound was 30.8 ± 1.7 weeks. The mean gestational age at birth was 36.3 ± 1.7 weeks. ROC curve analysis found the Hadlock III formula had the largest area under the curve (AUC) of 0.813 closely followed by Hadlock IV (AUC = 0.811) and Hadlock II (AUC = 0.808) for diagnosis of FGR correlating to neonatal SGA diagnosis. Hadlock II, Hadlock III, and Hadlock IV had the highest diagnostic accuracies when compared to the other EFW formulas.The Hadlock II, Hadlock III, and Hadlock IV formulas have comparable predictive performance in the optimal identification of FGR in fetuses with gastroschisis at 26-34 weeks'. A threshold of an EFW less than the 25.2th percentile is suggested.

Gastroschisis

Intrauterine growth restriction

Fetal growth

10.1002/jum.16108

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Citations (1)

Spontaneous rupture of uteroovarian veins in pregnancy: Two case reports

American Journal of Obstetrics and Gynecology (1987)

Michael R. Foley Jiri Sonek L.Michael Lavender Frederick P. Zuspan

Etiology

Uterine rupture

Third trimester

10.1016/0002-9378(87)90367-x

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Citations (24)

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Journal of Ultrasound in Medicine (2022)

Subspecialty Editors Samer Narouze J. Brian Fowlkes Stamatia Destounis Michelle L. Robbin

10.1002/jum.16011

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Citations (1)

Combined screening test for trisomy 21 – is it as efficient as we believe?

Journal of Perinatal Medicine (2016)

Marcin Wiecheć Agnieszka Nocuń Anna Knafel Ewa Wiercińska Jiri Sonek

To compare two first-trimester screening strategies: traditional combined screening and the one based on ultrasound markers only. We investigated the effect of maternal age (MA) on the screening performance of both of these strategies.This was a prospective observational study based on a non-selected mixed-risk population of 11,653 women referred for first-trimester screening. The study population was divided in two groups: combined screening (CS) and ultrasound-based screening (US). Absolute risk was calculated to determine the influence of MA on screening performance.The CS arm comprised 5145 subjects including 51 cases of trisomy 21 (T21), and the US arm comprised 5733 subjects including 87 subjects with T21. Seven hundred and seventy-five subjects were excluded from the study. For a false positive rate (FPR) of 3%, the detection rate (DR) of T21 in CS arm was 78% vs. 90% in US arm. For 5% FPR, DR was 84% and 94% in CS and US arm, respectively. MA had an influence on DR positive rates in CS: both DR and FPR for T21 increased with advance in MA.The US protocol showed higher DR of T21 compared to the CS one. It may be considered as a viable alternative to CS for T21 where access to biochemical testing is limited.

Trisomy

False positive rate

Medical screening

Screening test

10.1515/jpm-2016-0031

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Citations (8)

Impact of a new image enhancement technology on the nuchal translucency thickness

Archives of Gynecology and Obstetrics (2025)

Tania Elger Natalia Prodan Kristina Bettecken Jiri Sonek Karl Oliver Kagan

To examine the impact of a new image enhancement technique on the distribution of NT measurements. In this retrospective study, nuchal translucency (NT) images that were taken with the GE Voluson E22 ultrasound machine between May and September 2024 were collected. One operator took manual and automated NT measurements in an NT image without radiant enhancement mode followed by automated measurements in NT images with minimum, medium and maximum radiant mode. The automated measurement in the NT images without radiant mode were considered gold standard. The relative bias of the gold standard, the manual measurement and the automated measurements with the radiant enhancement technology were compared using median and 25–75th interquartile range as well as by the Wilcoxon test. The database search yielded 352 NT images from 101 pregnant women. Average maternal age of the study population was 34.0 years and average crown-rump length was 68.3. The median NT thickness was 1.7 mm for both the manual and automated measurements done without the use of radiant mode. The median automated measurement with minimum, medium and maximum radiant mode was 2.00, 2.05 and 2.10 mm, respectively. All automated measurements were significantly higher than the gold standard. The use of the radiant mode results in an increase in the NT thickness. This effect should be taken into account when calculating the risk for chromosomal abnormalities.

Nuchal translucency

10.1007/s00404-024-07924-1

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Frontomaxillary facial angles in screening for trisomy 21 at 14-23 weeks’ gestation

American Journal of Obstetrics and Gynecology (2007)

Jiri Sonek M. Borenstein Cathy Downing David S. McKenna Ran Neiger

Trisomy

10.1016/j.ajog.2007.03.059

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Citations (51)

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