A novel visible-light photoredox-catalyzed phosphinyloxy radical addition/cyclization cascade of arylphosphinic acids or arylphosphonic acid monoesters with alkynes has been developed, which provides an efficient and practical access to various phosphaisocoumarins by using a dual catalytic system containing an acridinium photosensitizer and a cobaloxime proton-reducing catalyst [Co(dmgH)2]PyCl at ambient temperature. This method has advantages of a broad substrate scope, mild condition, as well as no sacrificial oxidant.
Abstract magnified image A series of 3‐[(6‐chloropyridin‐3‐yl)methyl]‐6‐substituted‐6,7‐dihydro‐3 H ‐1,2,3‐triazolo[4,5‐ d ]pyrimidin‐7‐imines were designed and synthesized via a multi‐step sequence using 2‐chloro‐5‐(chloromethyl)‐pyridine as the starting material. Various primary aliphatic amines, hydrazine and hydrazide reacted with 3 to obtain the cyclization products 4 . Their structures were confirmed by 1 H NMR and elemental analyses, some of them were also confirmed by IR, 13 C NMR, MS and single crystal X‐ray diffraction. The preliminary bioassay indicated that some of the target compounds 4 displayed moderate to weak fungicidal activity and insecticidal activity.
A series of novel ( Z)‐ 1‐tert‐butyl (or phenyl)‐2‐(1 H ‐1,2,4‐triazol‐1‐yl)‐ethanone O ‐[2,4‐dimethylthiazole (or 4‐methyl‐1,2,3‐thiadiazole) −5‐carbonyl] oximes 5a – 5c and ( 1Z, 3Z)‐ 4,4‐dimethyl‐1‐substitutedphenyl‐2‐(1 H ‐1,2,4‐triazol‐1‐yl)‐pent‐1‐en‐3‐one O ‐[2,4‐dimethylthiazole (or 4‐methyl‐1,2,3‐thiadiazole)‐5‐carbonyl] oximes 6a – 6e were synthesized by the condensations of ( Z)‐ 1‐tert‐butyl (or phenyl)‐2‐(1 H ‐1,2,4‐triazol‐1‐yl)‐ethanone oximes 3 or ( 1Z, 3Z)‐ 4,4‐dimethyl‐1‐substitutedphenyl‐2‐(1 H ‐1,2,4‐triazol‐1‐yl)‐pent‐1‐en‐3‐one oximes 4 with 2,4‐dimethylthiazole‐5‐carbonyl chloride or 4‐methyl‐1,2,3‐thiadiazole‐5‐carbonyl chloride in the basic condition. Their structures were confirmed by IR, 1 H NMR, mass spectroscopy, and elemental analyses. The results of preliminary bioassays showed the title compounds 5 and 6 exhibited moderate to good fungicidal activities. For example, compound 6c possessed 86.4% inhibition against Fusarium oxysporum , and compound 6b exhibited 86.4 and 100% inhibition against Fusarium oxysporum and Cercospora arachidicola Hori at the concentration of 50 mg/L, respectively.
Abstract As one single membrane material could not fulfill the requests of chemical stability, mechanical strength, and resistance to pollution in practical applications. Modifications of the membrane to improve its separation performance were of great significance. In this study, UV irradiation grafting modification was employed and butyl acrylate was selected as a modification monomer for polyimide membrane to improve its lipophilicity and separation efficiency in lubricant solvent recovery. And effects of monomer concentration, irradiation distance, and grafting time on the grafting results and separation properties of modified polyimide membranes were investigated. The results exhibited that modified polyimide membranes obtained an enhanced lubricant retention rate compared with raw membranes, which increased from 66.5% to 93.1%. The industrial test for 40 days proved the great stability of modified polyimide membranes. Overall, this work confirmed the good industrial utilization potential of modified polyimide membranes and offered an effective way for lubricant solvent recovery.
In the title compound, C16H13Cl3N6O3S, the substituted triazole ring is bound via a methylene bridge to a chlorothiazole unit. There is evidence for significant electron delocalization in the triazolyl system. Both intra- and intermolecular hydrogen bonds are found in the structure.
Abstract A visible‐light‐driven radical‐mediated strategy for the in situ generation of aza‐ ortho ‐quinone methides from 2‐vinyl‐substituted anilines and alkyl radical precursors is described. This process enables an efficient multicomponent reaction of 2‐vinylanilines, halides, and sulfur ylides, and has a wide substrate scope and good functional group tolerance. Treatment of the cycloaddition products with a base leads to densely functionalized indoles in a single‐flask operation.
In the title compound, C14H16ClN7O2, the triazole ring carries cyano and formamidine substituents and is bound via a methylene bridge to a chloropyridine unit. There is evidence of significant electron delocalization in the triazolyl system. Intramolecular O—H⋯O and intermolecular C—H⋯N, C—H⋯O and O—H⋯N hydrogen bonds, together with strong π–π stacking interactions, stabilize the structure.
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