Vincenzo Grassia

University of Campania "Luigi Vanvitelli"

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Co-Authors

Letizia Perillo

University of Campania "Luigi Vanvitelli"

Ludovica Nucci

University of Campania "Luigi Vanvitelli"

Fabrizia d’Apuzzo

University of Campania "Luigi Vanvitelli"

Abdolreza Jamilian

University of Bolton

Felice Femiano

University of Campania "Luigi Vanvitelli"

Giuseppe Minervini

University of Campania "Luigi Vanvitelli"

Rossana Patricia Rotolo

University of Campania "Luigi Vanvitelli"

Rossella Femiano

University of Campania "Luigi Vanvitelli"

Gaetano Isola

University of Catania

Carlos Flores‐Mir

University of Alberta

Cooperative Institutions

University of Campania "Luigi Vanvitelli"

University of Naples Federico II

University of Bari Aldo Moro

University of Foggia

University of Messina

University of Milan

Sapienza University of Rome

Federico II University Hospital

Istituti di Ricovero e Cura a Carattere Scientifico

Azienda Ospedaliera Universitaria Università degli Studi della Campania Luigi Vanvitelli

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Micro-Raman spectroscopy during orthodontic tooth movement: Follow-up of gingival status

C. Camerlingo Fabrizia d’Apuzzo Vincenzo Grassia G. Parente Letizia Perillo

Micro-Raman spectroscopy (μ-RS) represents an appealing technique in dentistry, allowing the in-vitro detection of analytic structure and molecular composition changes of dental and oral cavity tissues. The gingival crevicular fluid (GCF) is a site-specific inflammatory exudate deriving from the epithelium lining of the gingival sulcus. The GCF analysis is useful in monitoring the factors related to the periodontal changes in response to diseases or mechanical stimuli. Therefore, the analysis of the GCF provides a simple and noninvasive diagnostic procedure to follow-up the periodontal ligament and bone remodeling during the orthodontic tooth movement. In this study, the potentiality of visible light μ-RS to evaluate GCF composition changes in the periodontium due to orthodontic forces was assessed. Sterile paper cones impregnated with GCF were collected from patients before and during an orthodontic treatment with fixed appliances and analyzed by μ-RS. A suitable numerical treatment based on wavelet-based algorithms was performed in order to eliminate the contribution of substrate and background signals on spectral data. The preliminary results showed changes in the secondary structure of Amide I band and an increase of carotenoid content in GCF during the orthodontic treatment.

Periodontium

Periodontal fiber

Gingival sulcus

Exudate

10.1109/biophotonics.2015.7304028

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Citations (3)

La frequenza delle anomalie dentarie nei pazienti affetti da cheilognatopalatoschisi

Mondo Ortodontico (2012)

Giuseppe Michele Padricelli A. Monsurrò Vincenzo Grassia Letizia Perillo

10.1016/j.mor.2011.11.001

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Citations (3)

Biomedical Journal of Scientific & Technical Research (2018)

Vincenzo Grassia Maddalena Vitale Alessio Paiusco Gianluigi Caccianiga Letizia Perillo

The biomodulation and the biostimulation of Low Level Laser Therapy (LLLT) promote wound healing, dentine repairing processes and stimulate the biological activity of human Periodontal Ligament Stem Cells (HPDLSCs), human Dental Pulp Stem Cells (HDPSCs), human Bone Marrow Stem Cells (HBMSCs) and human Adipose Stem Cells (HADSCs).The aim of the study was to review the literature on the LLLT effects on HPDLSCs, HDPSCs, HBMSCs and HADSCs.The electronic search was performed collecting articles in the PubMed, Medline, Scopus, Lilacs and Google Scholar databases from January 1990 to January 2018.LLLT was able to significantly increase HPDLSCs, HDPSCs, HBMSCs and HADSCs proliferation rate, stimulating osteogenic differentiation and opening new possibilities in the tissue regeneration.However, the research background on this topic showed high heterogeneity and the in vitro studies cannot always mimic the in vivo conditions.Thus, further clinical studies should be performed to determine the appropriate dose of irradiation in different patients.

10.26717/bjstr.4.2

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Effect of Obesity on the Respiratory Parameters in Children with Obstructive Sleep Apnea Syndrome

Children (2023)

Carolina Caliendo Rossella Femiano Giuseppina Rosaria Umano Stefano Martina Ludovica Nucci

The aim of the study was to investigate how obesity can influence sleep respiratory parameters in obstructive sleep apnea syndrome (OSAS) in children.The study analyzes 56 Caucasian children and adolescents aged 11 ± 2.79 years with a BMI > 5th percentiles and a PSQ value ≥ 0.33. Children were divided into Obesity Group (OG) with BMI ≥ 95th and Control Group (CG) with 5th < BMI > 95th percentile. All selected children underwent PG. Respiratory parameters AHI (Apnea-Hypopnea Index), SaO2 (Saturation of Oxygen), ODI (Oxygen Desaturation Index), and Nadir (the lowest value of SaO2 registered during PG) were extracted from the PG. AHI was used to divide the severity of OSAS into four levels: snoring (AHI ≤ 1), mild (AHI > 1 and ≤5), moderate (AHI > 5 and <10), and severe (AHI ≥ 10).The comparison analysis between the OG and CG showed a statistical significance only for ODI (p = 0.02). A statistically significant correlation between BMI and AHI (r = 0.02), SaO2 (r = 0.01), and Nadir O2 (r = 0.02) was found.There was no strong correlation between obesity and OSAS, but a positive association was found between BMI and AHI severity.

Oxygen Saturation

Hypopnea

Apnea–hypopnea index

Severe obesity

Nadir

10.3390/children10121874

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Citations (3)

КАРДИОЛОГИЯ УЗБЕКИСТАНА (2015)

Marco De Carlo Nuccia Morici Stefano Savonitto Vincenzo Grassia Paolo Sbarzaglia

Clinical endpoint

Stroke

ST elevation

10.1016/j.jcin.2014.12.240

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Citations (39)

Aesthetics in Orthodontics: Where We Are?

Journal of Orthodontics & Endodontics (2018)

Vincenzo Grassia

10.21767/2469-2980.100062

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Paediatric Orthodontics. Part 4: SEC III protocol in Class III malocclusion.

PubMed (2019)

Fabrizia d’Apuzzo Vincenzo Grassia Vincenzo Quinzi Marina Consuelo Vitale Giuseppe Marzo

SEC III protocol: Early treatment of dentoskeletal Class III malocclusions. The early treatment of dentoskeletal Class III malocclusion is one of the more challenging situations for orthodontists, mainly for the uncertainty of stable long-term results due to the interaction of both environmental and genetic aetiological factors. Several interceptive protocols have been proposed during the past decades. The SEC III protocol includes two occlusal acrylic Splints combined with Class III elastics and chin cup. The protocol was proposed to facilitate Class III dentoskeletal correction by eliminating the intercuspation and the tongue thrust with clockwise mandibular rotation and minimal dentoalveolar compensation. The main difference with all the other appliances is the vertical control, which is crucial in difficult cases such as hyperdivergent Class III malocclusions.

10.23804/ejpd.2019.20.04.14

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A Retrospective Study on Insertion Torque and Implant Stability Quotient (ISQ) as Stability Parameters for Immediate Loading of Implants in Fresh Extraction Sockets

BioMed Research International (2019)

Giuseppe Bavetta Giorgio Bavetta Valentina Randazzo Alessio Cavataio Carlo Paderni

To date, insertion torque value (ITV) and implant stability quotient (ISQ) obtained by the Osstell instrument are common clinical methods to assess the initial stability of an implant for a predictable loading procedure. The aim of this current study is to evaluate the ITV and ISQ as stability parameters as part of the decision-making protocol in the adoption of immediate loading in fresh extraction sockets.A total of 41 tapered implants were allocated into two groups: the test group (n = 11; 3 males and 8 females; mean age: 62.8 ± 10.7) which received 18 implants as type 1 fresh extraction sockets after teeth removal and the control group (n = 7; 4 males and 3 females; mean age: 65.4 ± 9.7) which received 23 implants placed in healed sockets for a period of at least 3 months. Both the ITV and ISQ data were recorded at the time of insertion (t0). Since ITV (test group) and ITV/ISQ (control group) values were useful for the immediate loading protocol, a screw-retained temporary crown was immediately loaded. ISQ values were recorded after a healing period of 4 months (t1).ITV mean values at t0 in test and control groups were, respectively, 48.61 ± 15.39 and 70.47 ± 14.71, whereas ISQ mean values were 57.55 ± 1.93 and 72.86 ± 5.25, respectively, showing a statistically significant difference (p value < 0.001). ISQ mean values at t1 in either the test or the control group were 68.68 ± 4.20 and 74.54 ± 4.17, not showing a statistical difference. The implant survival rate was 100% in both groups, and no surgical and prosthetic complications were reported during the study.In conclusion, this study remarked the presence of a residual gap that influenced the ISQ during implant insertion in fresh extraction sockets making this parameter not sufficient for a conclusive decision in the immediate loading, whereas the ITV alone showed to be the best parameter for a final substantial decision.

Implant stability quotient

Initial stability

10.1155/2019/9720419

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Citations (53)

Temporomandibular Disorders and Serological Tests in Patients with Rheumatoid Arthritis

Applied Sciences (2023)

Fabrizia d’Apuzzo Rossana Patricia Rotolo Mario Fordellone Giovanna Cuomo Abdolreza Jamilian

Background: Rheumatoid Arthritis (RA) is a systemic and chronic autoimmune disease with inflammation at the synovial joints. The purposes of this study were to evaluate the correlation between serological variables and temporomandibular disorders (TMDs) in patients diagnosed with RA, evaluated through diagnostic criteria for temporomandibular disorders (DC/TMD), and to check the influence of comorbidities on the different TMD signs and symptoms, or any serological variables. Methods: This observational cohort research study included seventeen patients affected by RA. The comorbidities and some variables from the initial serological analyses were collected from the clinical rheumatological charts. Then, the presence of any of the following TMD signs/symptoms, temporal myalgia, temporomandibular joint arthralgia, click or crepitus, was evaluated through the symptom questionnaire of the DC/TMD during clinical evaluation following the DC/TMD examination form. Results: Rheumatoid factor (RF), anticitrullinated protein antibodies (ACPA), and anti-nuclear antibody (ANA) positivity were present in 82.4%, 52.9%, and 41.2% of patients, respectively. Indicators of tissue inflammation were evaluated with median values of 21 mm/h for erythrocyte sedimentation rate (ESR) and 0.50 mg/dL for C-reactive protein (CRP). The RA patients presented comorbidities such as hypertension in 70.6% and diabetes in 23.5%. Negative ACPA had a significant association with myalgia (p = 0.03), and positive ANA was significantly associated with crepitus (p = 0.05). Conclusion: ANA and ACPA evaluation can be considered predictive serological tests associated with specific TMDs. Conversely, no influence of any comorbidities was found between different TMD signs and symptoms, or any serological variables.

myalgia

Rheumatoid factor

Erythrocyte sedimentation rate

10.3390/app132011488

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Citations (6)

Factors Affecting Patient Compliance during Orthodontic Treatment with Aligners: Motivational Protocol and Psychological Well-Being

Turkish Journal of Orthodontics (2023)

Letizia Perillo Fabrizia d’Apuzzo Franca De Gregorio Vincenzo Grassia Manuel Barbetti

Main Points• The psychological profile of individuals did not correlate with their compliance throughout the treatment, but the psychological well-being (PWB) questionnaire showed higher scores after 12 months of CA. • The motivational protocol used in a group of adult patients already willing to improve their smile with clear and removable aligners did not show significant differences in treatment progress.• The clinical progress evaluated both on gypsum casts and on digital clin-check demonstrated the efficacy of CA in patients with good adherence to treatment.

Patient Compliance

10.4274/turkjorthod.2022.2021.0255

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Citations (6)