Gonzalo Urcelay

Pontificia Universidad Católica de Chile

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Felipe Heusser

Pontificia Universidad Católica de Chile

Pedro Becker

Pontificia Universidad Católica de Chile

Edward L. Bove

University of Michigan–Ann Arbor

Ralph S. Mosca

NYU Langone Health

Daniel Springmüller

Pontificia Universidad Católica de Chile

Patricia Frangini

Pontificia Universidad Católica de Chile

Francisco Garay

Comisión de Investigaciones Científicas

R. Gonzalez

Moffitt Cancer Center

Cristián Clavería

Pontificia Universidad Católica de Chile

Roberto Fumero

Politecnico di Milano

Cooperative Institutions

Pontificia Universidad Católica de Chile

University of Michigan–Ann Arbor

Hospital Clínico de la Universidad Católica

University of Chile

C. S. Mott Children's Hospital

Complejo Asistencial Sótero del Río

Michigan Medicine

Great Ormond Street Hospital

Politecnico di Milano

King's College London

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Nitric Oxide in Pulmonary Arteriovenous Malformations and Fontan Procedure

The Annals of Thoracic Surgery (2005)

Gonzalo Urcelay Arturo Borzutzky Pedro Becker María E. Castillo

Fontan Procedure

10.1016/j.athoracsur.2003.12.095

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Citations (8)

[Cardiac involvement in Kawasaki disease].

PubMed (1989)

Gonzalo Urcelay Ignacio Hernández‐González O Farrú G Arcil Fabián Godoy

Cardiovascular complications (CVC) of Kawasaki disease (KD) are described in 15 affected children (10 boys, mean age 18.5 months). Clinical records, electrocardiographic tracings (ECG) and bidimensional echocardiograms (BDE) were analysed. In each case the first BDE was done at clinical diagnosis (mean time 10 days from initial symptoms of disease), then at weekly intervals for the first month and each two weeks along the second month. In children showing persistent coronary artery lesions (CAL) BDE was repeated monthly and in patients without CVC at three month intervals. During follow up, no definite clinical evidence of miocardial ischemia was found, but abnormal BDE recordings were obtained from 12/15 patient: CAL in 9/15; right ventricular, left ventricular and aortic enlargement in 3/15. CAL were located at the left coronary artery (LCA) in 3/9 (one LCA aneurysm) and at both coronary arteries in 6/9 (including 3 cases with bilateral aneurysms). All patients were given aspirin and seven were also treated with intravenous gammaglobulin, this last at day 9 (mean) of disease, but 5 of them developed CVC, including 3 cases of CAL.

Coronary arteries

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Citations (2)

Cierre perventricular de la comunicación interventricular múltiple con dispositivo Amplatzer

Revista Española de Cardiología (2004)

Pedro Becker Patricia Frangini Felipe Heusser Gonzalo Urcelay Francisco Garay

10.1016/s0300-8932(04)77267-x

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Citations (8)

[Radiofrequency fulguration for supraventricular tachycardia in pediatrics].

PubMed (1996)

Felipe Heusser Acevedo Ismael A. Vergara A Fajuri R Neghme

Supraventricular tachycardias (SVT) are the most frequent cause of tachycardia in children. Its pharmacological treatment has adverse effects, is not curative, and is not always effective. During the last few years radiofrequency ablation (RF-A) has changed the treatment. The purpose of this study is to evaluate our experience in RF-A in children with SVT. Between 1990 and 1995, 92 patients (1 month to 17 years old) underwent electrophysiological study after the diagnosis of SVT. RF-A was attempted in 55 patients with accessory pathways (AP), slow-pathway of the atrioventricular node, or ectopic focus. The site of ablation was decided according to the electrical signals and the catheter position. The success of the RF-A was confirmed by the interruption of the tachycardia, the change in the sequence of activation of the intracardiac signals, the regression of the preexcitation, and the inability to reinduce tachycardia. RF-A was successful in 81% of the patients; 88% in those with a left AP, 56% in those with a right AP, and 100% in those with nodal reentry. Complications were seen in 7% of the patients: 3 with arterial obstruction, one with a minimal pneumothorax, and one with cardiac tamponade. During a follow up of 16.6 months there was no relapse nor late complications. We conclude that RF-A is a safe and effective procedure in pediatric patients with SVT.

Supraventricular Tachycardia

Reentry

Atrioventricular node

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Citations (1)

Acquired coronary artery fistulae after right ventricular myotomy and/or myomectomy for congenital heart disease

The American Journal of Cardiology (1995)

Gonzalo Urcelay Achi Ludomirsky Roger P. Vermilion Gerald A. Serwer Ralph S. Mosca

Ventricular Function

10.1016/s0002-9149(99)80568-2

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Citations (11)

Resultados de un programa nacional de trasplante cardiaco pediátrico: fortalezas y debilidades

Revista chilena de pediatría (2017)

Pedro Becker Santiago Besa Sergio Riveros R. Gonzalez Alfonso Navia

Introduction: Pediatric heart transplantation is an effective therapy to treat advanced heart failure in children.Objectives: To analyze the immediate and mid-term results of pediatric patients listed for heart transplantation.Material and Methods: Registration of patients admitted to our transplant protocol between October 2001 and July 2016 were reviewed, analyzing demographic data, diagnosis, status at the time of listing, waiting time until transplantation, donor data, use of ventricular assist device, hemodynamic data, complications and global mortality.Results: Thirthy patients where included with a mean age of 9.4 years (1 month to 15 years).The most frequent diagnosis was dilated cardiomyopathy in 24 patients (80%).The status was I (urgency) in 19 cases and II in 11 cases.Ten patients died on the waiting list (33,3%) at an average of 52 days (13-139 days).Fourteen were transplanted (46.7%), with a waiting time of 199.6 days (4-586 days).Nine patients required mechanical support (30%).All patients received triple association of immunosuppression.One patient died 16 days post transplant due to primary graft failure (7.1%).The average follow-up was 43 months (0.5-159 months).Two patients died later on (82 and 55 months), both due to secondary rejection because of voluntary cessation of immunosuppressive therapy.Survival at 1 and 5 years was 93% and 74%, respectively.Conclusions: Our program has successfully transplanted 50% of patients enrolled, with good medium-term survival.A significant proportion of patients were listed urgently and 34.5% died on the waiting list.

Immunosuppression

Waiting list

Heart transplants

Medical record

10.4067/s0370-41062017000300009

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Citations (1)

Cardiovascular magnetic resonance findings in a pediatric population with isolated left ventricular non-compaction

Journal of Cardiovascular Magnetic Resonance (2012)

Sergio Uribe L. A. Mejía Cadavid Tarique Hussain Rodrigo Parra Gonzalo Urcelay

Isolated Left Ventricular Non-compaction (LVNC) is an uncommon disorder characterized by the presence of increased trabeculations and deep intertrabecular recesses. In adults, it has been found that Ejection Fraction (EF) decreases significantly as non-compaction severity increases. In children however, there are a few data describing the relation between anatomical characteristics of LVNC and ventricular function. We aimed to find correlations between morphological features and ventricular performance in children and young adolescents with LVNC using Cardiovascular Magnetic Resonance (CMR). 15 children with LVNC (10 males, mean age 9.7 y.o., range 0.6 - 17 y.o.), underwent a CMR scan. Different morphological measures such as the Compacted Myocardial Mass (CMM), Non-Compaction (NC) to the Compaction (C) distance ratio, Compacted Myocardial Area (CMA) and Non-Compacted Myocardial Area (NCMA), distribution of NC, and the assessment of ventricular wall motion abnormalities were performed to investigate correlations with ventricular performance. EF was considered normal over 53%. The distribution of non-compaction in children was similar to published adult data with a predilection for apical, mid-inferior and mid-lateral segments. Five patients had systolic dysfunction with decreased EF. The number of affected segments was the strongest predictor of systolic dysfunction, all five patients had greater than 9 affected segments. Basal segments were less commonly affected but they were affected only in these five severe cases. The segmental pattern of involvement of non-compaction in children is similar to that seen in adults. Systolic dysfunction in children is closely related to the number of affected segments.

Angiology

Basal (medicine)

10.1186/1532-429x-14-9

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Citations (19)

[Dilated cardiomyopathy in children].

PubMed (2020)

Gonzalo Urcelay

Pediatric cardiomyopathies are infrequent diseases of the cardiac muscle, with an annual inciden ce of 1.1 to 1.2 per 100,000 children. Dilated cardiomyopathy (DCM) is the predominant form, characterized by ventricular dilatation and systolic dysfunction. Etiologies are multiple, with at least 50%-70% of cases being idiopathic. When assessing a child with DCM, secondary potentially reversible causes must be ruled out. The main diagnostic tool is the echocardiogram which allows the identification of cardiac phenotype, to establish the degree of functional compromise, and res ponse to medical therapy. Prognosis is limited but more favorable in infants younger than 1 year at the onset, post myocarditis, or with a lesser degree of ventricular dysfunction. At least 20% of patients may recover ventricular function in the first 2 years after the onset and 40%-50% may die or need heart transplant in the first 5 years. Medical therapy is mainly based on adult experience with limited scientific evidence in children. Heart transplant is the therapy of choice in patients with end-stage disease, with excellent short- and medium-term survival. A significant proportion of patients may require stabilization on the waiting list, including the use of mechanical circulatory support as a bridge to transplantation. The purpose of this revision is to update the available infor mation on etiology, physiopathological mechanisms, prognostic factors, and management of DCM in children.

Etiology

Dilated Cardiomyopathy

10.32641/rchped.vi91i6.2851

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Citations (0)

size, vascular resistances, and heart rate Modeling of the Norwood circulation: effects of shunt

Gonzalo Urcelay Edward L. Bove Tain‐Yen Hsia Marc R. de Leval Francesco Migliavacca

Norwood procedure

Circulation (fluid dynamics)

Systemic circulation

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